Domain Predictions — View

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IPR004468

Source: InterPro

Description

IPR004468 is a CTP synthase.

<p>CTP synthase is involved in pyrimidine ribonucleotide/ribonucleoside metabolism, catalysing the synthesis of CTP from UTP by amination of the pyrimidine ring at the 4-position [[cite:PUB00012378]]. The enzyme exists as a dimer which consists of an N-terminal synthetase domain and C-terminal glutaminase domain that aggregates as a tetramer. This gene has been found roughly 500 bp upstream of enolase in both beta (Nitrosomonas europaea) and gamma (Escherichia coli) subdivisions of Proteobacterium [[cite:PUB00007677]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

GO term	Namespace	Name	Definition	Relationships
GO:0003883 View details of GO:0003883 AmiGO InterPro QuickGO	Molecular function	CTP synthase activity	Catalysis of the reaction: ATP + UTP + NH3 = ADP + phosphate + CTP.	Subterm of GO:0016879
GO:0006221 View details of GO:0006221 AmiGO InterPro QuickGO	Biological process	Pyrimidine nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	Subterm of GO:0006220 GO:0009165 GO:0072528

Associated Lotus transcripts 17

Transcript	Name	Description	Predicted domains	Domain count
Lj0g3v0016119.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	CTP synthase [Medicago truncatula] gi\|357442321\|ref\|XP_003591438.1\|	Domains G3DSA:3.40.50.300 IPR004468 IPR017456 IPR027417 NON_CYTOPLASMIC_DOMAIN PF06418 PTHR11550 PTHR11550:SF7 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SignalP-noTM_EUK	13
Lj0g3v0281729.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: CTP synthase 1-like [Cicer arietinum] gi\|502154191\|ref\|XP_004509615.1\|	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 NON_CYTOPLASMIC_DOMAIN PF00117 PF06418 PS51257 PS51273 PTHR11550 PTHR11550:SF11 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF52317 SSF52540 TIGR00337	21
Lj0g3v0332949.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: CTP synthase-like isoform X1 [Cicer arietinum] gi\|502182968\|ref\|XP_004517030.1\|	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 MF_01227 NON_CYTOPLASMIC_DOMAIN PF00117 PF06418 PS51257 PS51273 PTHR11550 PTHR11550:SF11 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF52317 SSF52540 TIGR00337 cd01746 cd03113 mobidb-lite	26
Lj3g3v0937760.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: CTP synthase-like isoform 1 [Glycine max] gi\|356525714\|ref\|XP_003531468.1\|	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 MF_01227 NON_CYTOPLASMIC_DOMAIN PF00117 PF06418 PS51257 PS51273 PTHR11550 PTHR11550:SF11 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF52317 SSF52540 TIGR00337 cd01746 cd03113	25
Lj5g3v1601850.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: CTP synthase-like [Cicer arietinum] gi\|502117735\|ref\|XP_004495920.1\|	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 PF00117 PF06418 PS51273 PTHR11550 PTHR11550:SF7 SSF52317 SSF52540 cd01746	16
Lj5g3v1601850.2 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: CTP synthase-like [Cicer arietinum] gi\|502117735\|ref\|XP_004495920.1\|	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 PF00117 PF06418 PS51273 PTHR11550 PTHR11550:SF7 SSF52317 SSF52540 cd01746	16
Lj5g3v1601850.3 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: CTP synthase-like [Cicer arietinum] gi\|502117735\|ref\|XP_004495920.1\|	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 MF_01227 NON_CYTOPLASMIC_DOMAIN PF00117 PF06418 PS51273 PTHR11550 PTHR11550:SF7 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF52317 SSF52540 TIGR00337 cd01746 cd03113	24
LotjaGi3g1v0130200.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	CTP synthase; TAIR: AT3G12670.1 CTP synthase family protein; Swiss-Prot: sp\|P70698\|PYRG1_MOUSE CTP synthase 1; TrEMBL-Plants: tr\|I1KTT7\|I1KTT7_SOYBN CTP synthase; Found in the gene: LotjaGi3g1v0130200	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 MF_01227 NON_CYTOPLASMIC_DOMAIN PF00117 PF06418 PS51257 PS51273 PTHR11550 PTHR11550:SF26 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF52317 SSF52540 TIGR00337 cd01746 cd03113	25
LotjaGi3g1v0130200.2 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	CTP synthase; TAIR: AT3G12670.1 CTP synthase family protein; Swiss-Prot: sp\|P70698\|PYRG1_MOUSE CTP synthase 1; TrEMBL-Plants: tr\|I1KTT7\|I1KTT7_SOYBN CTP synthase; Found in the gene: LotjaGi3g1v0130200	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 MF_01227 NON_CYTOPLASMIC_DOMAIN PF00117 PF06418 PS51257 PS51273 PTHR11550 PTHR11550:SF26 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF52317 SSF52540 TIGR00337 cd01746 cd03113	25
LotjaGi3g1v0300500.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	CTP synthase; TAIR: AT3G12670.1 CTP synthase family protein; Swiss-Prot: sp\|Q54V77\|PYRG_DICDI CTP synthase; TrEMBL-Plants: tr\|A0A072TPJ2\|A0A072TPJ2_MEDTR CTP synthase; Found in the gene: LotjaGi3g1v0300500	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 MF_01227 NON_CYTOPLASMIC_DOMAIN PF00117 PF06418 PS51257 PS51273 PTHR11550 PTHR11550:SF26 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF52317 SSF52540 TIGR00337 cd01746 cd03113 mobidb-lite	26
LotjaGi4g1v0149400.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	CTP synthase; TAIR: AT1G30820.1 CTP synthase family protein; Swiss-Prot: sp\|P70698\|PYRG1_MOUSE CTP synthase 1; TrEMBL-Plants: tr\|A0A0S3R418\|A0A0S3R418_PHAAN CTP synthase; Found in the gene: LotjaGi4g1v0149400	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 PF00117 PF06418 PS51273 PTHR11550 PTHR11550:SF29 SSF52317 SSF52540 cd01746 cd03113	17
LotjaGi4g1v0149400.2 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	CTP synthase; TAIR: AT1G30820.1 CTP synthase family protein; Swiss-Prot: sp\|P70698\|PYRG1_MOUSE CTP synthase 1; TrEMBL-Plants: tr\|A0A0S3R418\|A0A0S3R418_PHAAN CTP synthase; Found in the gene: LotjaGi4g1v0149400	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 MF_01227 NON_CYTOPLASMIC_DOMAIN PF00117 PF06418 PS51257 PS51273 PTHR11550 PTHR11550:SF26 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF52317 SSF52540 TIGR00337 cd01746 cd03113	25
LotjaGi5g1v0247000.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	CTP synthase; TAIR: AT4G02120.1 CTP synthase family protein; Swiss-Prot: sp\|Q54V77\|PYRG_DICDI CTP synthase; TrEMBL-Plants: tr\|I1JBI0\|I1JBI0_SOYBN CTP synthase; Found in the gene: LotjaGi5g1v0247000	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 MF_01227 NON_CYTOPLASMIC_DOMAIN PF00117 PF06418 PS51273 PTHR11550 PTHR11550:SF32 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF52317 SSF52540 TIGR00337 cd01746 cd03113	24
LotjaGi5g1v0247000.2 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	CTP synthase; TAIR: AT4G02120.1 CTP synthase family protein; Swiss-Prot: sp\|Q54V77\|PYRG_DICDI CTP synthase; TrEMBL-Plants: tr\|I1JBI0\|I1JBI0_SOYBN CTP synthase; Found in the gene: LotjaGi5g1v0247000	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 MF_01227 NON_CYTOPLASMIC_DOMAIN PF00117 PF06418 PS51273 PTHR11550 PTHR11550:SF32 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF52317 SSF52540 TIGR00337 cd01746 cd03113	24
LotjaGi5g1v0247000.3 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	CTP synthase; TAIR: AT4G02120.3 CTP synthase family protein; Swiss-Prot: sp\|Q54V77\|PYRG_DICDI CTP synthase; TrEMBL-Plants: tr\|A0A151U4J8\|A0A151U4J8_CAJCA CTP synthase; Found in the gene: LotjaGi5g1v0247000	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 NON_CYTOPLASMIC_DOMAIN PF00117 PF06418 PS51273 PTHR11550 PTHR11550:SF32 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF52317 SSF52540 TIGR00337 cd01746 cd03113	23
LotjaGi5g1v0247000.4 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	CTP synthase; TAIR: AT4G02120.1 CTP synthase family protein; Swiss-Prot: sp\|Q54V77\|PYRG_DICDI CTP synthase; TrEMBL-Plants: tr\|I1JBI0\|I1JBI0_SOYBN CTP synthase; Found in the gene: LotjaGi5g1v0247000	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 NON_CYTOPLASMIC_DOMAIN PF00117 PF06418 PS51273 PTHR11550 PTHR11550:SF32 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF52317 SSF52540 TIGR00337 cd01746 cd03113	23
LotjaGi5g1v0247000.5 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	CTP synthase; TAIR: AT4G02120.1 CTP synthase family protein; Swiss-Prot: sp\|Q54V77\|PYRG_DICDI CTP synthase; TrEMBL-Plants: tr\|I1JBI0\|I1JBI0_SOYBN CTP synthase; Found in the gene: LotjaGi5g1v0247000	Domains G3DSA:3.40.50.300 G3DSA:3.40.50.880 IPR004468 IPR017456 IPR017926 IPR027417 IPR029062 IPR033828 NON_CYTOPLASMIC_DOMAIN PF00117 PF06418 PS51273 PTHR11550 PTHR11550:SF32 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF52317 SSF52540 TIGR00337 cd01746 cd03113	23

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain	Source	Observations	Saturation (%)
cd03113	CDD	1	5.88