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IPR017456

Description

IPR017456 is a CTP synthase, N-terminal.

<p>CTP synthase is involved in pyrimidine ribonucleotide/ribonucleoside metabolism, catalysing the synthesis of CTP from UTP by amination of the pyrimidine ring at the 4-position [[cite:PUB00012378]]. The enzyme exists as a dimer which consists of an N-terminal synthetase domain and C-terminal glutaminase domain that aggregates as a tetramer. This gene has been found roughly 500 bp upstream of enolase in both beta (Nitrosomonas europaea) and gamma (Escherichia coli) subdivisions of Proteobacterium [[cite:PUB00007677]].</p> <p>This entry represents the N-terminal synthetase domain of CTP synthase.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function CTP synthase activity Catalysis of the reaction: ATP + UTP + NH3 = ADP + phosphate + CTP.
Biological process Pyrimidine nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.

Associated Lotus transcripts 17

Transcript Name Description Predicted domains Domain count
CTP synthase [Medicago truncatula] gi|357442321|ref|XP_003591438.1| 13
PREDICTED: CTP synthase 1-like [Cicer arietinum] gi|502154191|ref|XP_004509615.1| 21
PREDICTED: CTP synthase-like isoform X1 [Cicer arietinum] gi|502182968|ref|XP_004517030.1| 26
PREDICTED: CTP synthase-like isoform 1 [Glycine max] gi|356525714|ref|XP_003531468.1| 25
PREDICTED: CTP synthase-like [Cicer arietinum] gi|502117735|ref|XP_004495920.1| 16
PREDICTED: CTP synthase-like [Cicer arietinum] gi|502117735|ref|XP_004495920.1| 16
PREDICTED: CTP synthase-like [Cicer arietinum] gi|502117735|ref|XP_004495920.1| 24
CTP synthase; TAIR: AT3G12670.1 CTP synthase family protein; Swiss-Prot: sp|P70698|PYRG1_MOUSE CTP synthase 1; TrEMBL-Plants: tr|I1KTT7|I1KTT7_SOYBN CTP synthase; Found in the gene: LotjaGi3g1v0130200 25
CTP synthase; TAIR: AT3G12670.1 CTP synthase family protein; Swiss-Prot: sp|P70698|PYRG1_MOUSE CTP synthase 1; TrEMBL-Plants: tr|I1KTT7|I1KTT7_SOYBN CTP synthase; Found in the gene: LotjaGi3g1v0130200 25
CTP synthase; TAIR: AT3G12670.1 CTP synthase family protein; Swiss-Prot: sp|Q54V77|PYRG_DICDI CTP synthase; TrEMBL-Plants: tr|A0A072TPJ2|A0A072TPJ2_MEDTR CTP synthase; Found in the gene: LotjaGi3g1v0300500 26
CTP synthase; TAIR: AT1G30820.1 CTP synthase family protein; Swiss-Prot: sp|P70698|PYRG1_MOUSE CTP synthase 1; TrEMBL-Plants: tr|A0A0S3R418|A0A0S3R418_PHAAN CTP synthase; Found in the gene: LotjaGi4g1v0149400 17
CTP synthase; TAIR: AT1G30820.1 CTP synthase family protein; Swiss-Prot: sp|P70698|PYRG1_MOUSE CTP synthase 1; TrEMBL-Plants: tr|A0A0S3R418|A0A0S3R418_PHAAN CTP synthase; Found in the gene: LotjaGi4g1v0149400 25
CTP synthase; TAIR: AT4G02120.1 CTP synthase family protein; Swiss-Prot: sp|Q54V77|PYRG_DICDI CTP synthase; TrEMBL-Plants: tr|I1JBI0|I1JBI0_SOYBN CTP synthase; Found in the gene: LotjaGi5g1v0247000 24
CTP synthase; TAIR: AT4G02120.1 CTP synthase family protein; Swiss-Prot: sp|Q54V77|PYRG_DICDI CTP synthase; TrEMBL-Plants: tr|I1JBI0|I1JBI0_SOYBN CTP synthase; Found in the gene: LotjaGi5g1v0247000 24
CTP synthase; TAIR: AT4G02120.3 CTP synthase family protein; Swiss-Prot: sp|Q54V77|PYRG_DICDI CTP synthase; TrEMBL-Plants: tr|A0A151U4J8|A0A151U4J8_CAJCA CTP synthase; Found in the gene: LotjaGi5g1v0247000 23
CTP synthase; TAIR: AT4G02120.1 CTP synthase family protein; Swiss-Prot: sp|Q54V77|PYRG_DICDI CTP synthase; TrEMBL-Plants: tr|I1JBI0|I1JBI0_SOYBN CTP synthase; Found in the gene: LotjaGi5g1v0247000 23
CTP synthase; TAIR: AT4G02120.1 CTP synthase family protein; Swiss-Prot: sp|Q54V77|PYRG_DICDI CTP synthase; TrEMBL-Plants: tr|I1JBI0|I1JBI0_SOYBN CTP synthase; Found in the gene: LotjaGi5g1v0247000 23

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd03113 CDD 1 5.88