Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR006592

Description

IPR006592 is a RNA polymerase, N-terminal.

<p>The task of transcribing nuclear genes is shared between three RNA polymerases in eukaryotes: RNA polymerase (pol) I synthesizes the large rRNA, pol II synthesizes mRNA and pol III synthesizes tRNA and 5S rRNA [[cite:PUB00028105]]. Pol I transcription is localised to discrete sites called nucleoli; these can be likened to ribosome factories, in which rRNA is synthesised by pol I in the fibrillar centres and then processed and assembled into ribosomes in the surrounding granular regions [[cite:PUB00028106]]. Prokaryotes, in contrast, posses a single RNA polymerase, with transcription being controlled by the particular signam factor interacting with the catalytic core.</p> <p>This entry describes an N-terminal conserved region which can be found in the largest subunits of prokaryoptic and eukaryotic RNA polymerases.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
Molecular function DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
Biological process Transcription, DNA-templated The cellular synthesis of RNA on a template of DNA.

Associated Lotus transcripts 20

Transcript Name Description Predicted domains Domain count
PREDICTED: DNA-directed RNA polymerase E subunit 1-like [Cicer arietinum] gi|502158103|ref|XP_004511031.1| 15
PREDICTED: DNA-directed RNA polymerase E subunit 1-like [Cicer arietinum] gi|502158103|ref|XP_004511031.1| 10
PREDICTED: DNA-directed RNA polymerase II subunit RPB1-like [Cicer arietinum] gi|502161489|ref|XP_004512182.1| 15
PREDICTED: DNA-directed RNA polymerase II subunit RPB1-like [Cicer arietinum] gi|502161489|ref|XP_004512182.1| 29
DNA-directed RNA polymerase subunit; TAIR: AT5G60040.1 nuclear RNA polymerase C1; Swiss-Prot: sp|F4JXF9|NRPC1_ARATH DNA-directed RNA polymerase III subunit 1; TrEMBL-Plants: tr|I1LK95|I1LK95_SOYBN DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi1g1v0634400 29
DNA-directed RNA polymerase subunit; TAIR: AT4G35800.1 RNA polymerase II large subunit; Swiss-Prot: sp|P18616|NRPB1_ARATH DNA-directed RNA polymerase II subunit 1; TrEMBL-Plants: tr|V7CLS7|V7CLS7_PHAVU DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi2g1v0377500 38
DNA-directed RNA polymerase subunit; TAIR: AT4G35800.1 RNA polymerase II large subunit; Swiss-Prot: sp|P18616|NRPB1_ARATH DNA-directed RNA polymerase II subunit 1; TrEMBL-Plants: tr|V7CLS7|V7CLS7_PHAVU DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi2g1v0377500 38
DNA-directed RNA polymerase subunit; TAIR: AT4G35800.1 RNA polymerase II large subunit; Swiss-Prot: sp|P18616|NRPB1_ARATH DNA-directed RNA polymerase II subunit 1; TrEMBL-Plants: tr|V7CLS7|V7CLS7_PHAVU DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi2g1v0377500 38
DNA-directed RNA polymerase subunit; TAIR: AT4G35800.1 RNA polymerase II large subunit; Swiss-Prot: sp|P18616|NRPB1_ARATH DNA-directed RNA polymerase II subunit 1; TrEMBL-Plants: tr|V7CLS7|V7CLS7_PHAVU DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi2g1v0377500 38
DNA-directed RNA polymerase subunit; TAIR: AT4G35800.1 RNA polymerase II large subunit; Swiss-Prot: sp|P18616|NRPB1_ARATH DNA-directed RNA polymerase II subunit 1; TrEMBL-Plants: tr|V7CLS7|V7CLS7_PHAVU DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi2g1v0377500 38
DNA-directed RNA polymerase subunit; TAIR: AT1G63020.1 nuclear RNA polymerase D1A; Swiss-Prot: sp|Q9LQ02|NRPD1_ARATH DNA-directed RNA polymerase IV subunit 1; TrEMBL-Plants: tr|G7KER5|G7KER5_MEDTR DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi2g1v0430800 19
DNA-directed RNA polymerase subunit; TAIR: AT1G63020.1 nuclear RNA polymerase D1A; Swiss-Prot: sp|Q9LQ02|NRPD1_ARATH DNA-directed RNA polymerase IV subunit 1; TrEMBL-Plants: tr|G7KER5|G7KER5_MEDTR DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi2g1v0430800 24
DNA-directed RNA polymerase subunit; TAIR: AT1G63020.1 nuclear RNA polymerase D1A; Swiss-Prot: sp|Q9LQ02|NRPD1_ARATH DNA-directed RNA polymerase IV subunit 1; TrEMBL-Plants: tr|G7KER5|G7KER5_MEDTR DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi2g1v0430800 24
DNA-directed RNA polymerase subunit; TAIR: AT1G63020.1 nuclear RNA polymerase D1A; Swiss-Prot: sp|Q9LQ02|NRPD1_ARATH DNA-directed RNA polymerase IV subunit 1; TrEMBL-Plants: tr|G7KER5|G7KER5_MEDTR DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi2g1v0430800 19
DNA-directed RNA polymerase subunit; TAIR: AT2G40030.1 nuclear RNA polymerase D1B; Swiss-Prot: sp|Q5D869|NRPE1_ARATH DNA-directed RNA polymerase V subunit 1; TrEMBL-Plants: tr|K7M0Q7|K7M0Q7_SOYBN DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi3g1v0318900 19
DNA-directed RNA polymerase subunit; TAIR: AT2G40030.1 nuclear RNA polymerase D1B; Swiss-Prot: sp|Q5D869|NRPE1_ARATH DNA-directed RNA polymerase V subunit 1; TrEMBL-Plants: tr|K7M0Q7|K7M0Q7_SOYBN DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi3g1v0318900 19
DNA-directed RNA polymerase subunit; TAIR: AT2G40030.1 nuclear RNA polymerase D1B; Swiss-Prot: sp|Q5D869|NRPE1_ARATH DNA-directed RNA polymerase V subunit 1; TrEMBL-Plants: tr|G7LG09|G7LG09_MEDTR DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi3g1v0318900 14
DNA-directed RNA polymerase subunit; TAIR: AT2G40030.1 nuclear RNA polymerase D1B; Swiss-Prot: sp|Q5D869|NRPE1_ARATH DNA-directed RNA polymerase V subunit 1; TrEMBL-Plants: tr|G7LG09|G7LG09_MEDTR DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi3g1v0318900 16
DNA-directed RNA polymerase subunit; TAIR: AT2G40030.1 nuclear RNA polymerase D1B; Swiss-Prot: sp|Q5D869|NRPE1_ARATH DNA-directed RNA polymerase V subunit 1; TrEMBL-Plants: tr|K7M0Q7|K7M0Q7_SOYBN DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi3g1v0319100 19
DNA-directed RNA polymerase subunit; TAIR: AT3G57660.1 nuclear RNA polymerase A1; Swiss-Prot: sp|Q9SVY0|NRPA1_ARATH DNA-directed RNA polymerase I subunit 1; TrEMBL-Plants: tr|A0A151QTE2|A0A151QTE2_CAJCA DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi5g1v0147900 28

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 5.00