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IPR035985

Source: InterPro

Description

IPR035985 is a Ubiquitin-activating enzyme.

<p>Ubiquitin-activating enzyme (E1 enzyme) [[cite:PUB00000623], [cite:PUB00005373]] activates ubiquitin by first adenylating with ATP its C-terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thiolester and free AMP. Later the ubiquitin moiety is transferred to a cysteine residue on one of the many forms of ubiquitin- conjugating enzymes (E2).</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0008641
Molecular function Ubiquitin-like modifier activating enzyme activity Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.
Subterm of

Associated Lotus transcripts 30

Transcript Name Description Predicted domains Domain count
LotjaGi1g1v0025600.1
– Adenylyltransferase and sulfurtransferase MOCS3; TAIR: AT5G55130.1 co-factor for nitrate, reductase and xanthine dehydrogenase 5; Swiss-Prot: sp|Q9ZNW0|MOCS3_ARATH Adenylyltransferase and sulfurtransferase MOCS3; TrEMBL-Plants: tr|G7K8M6|G7K8M6_MEDTR Adenylyltransferase and sulfurtransferase MOCS3; Found in the gene: LotjaGi1g1v0025600
Domains
18
LotjaGi1g1v0025600.2
– Adenylyltransferase and sulfurtransferase MOCS3; TAIR: AT5G55130.1 co-factor for nitrate, reductase and xanthine dehydrogenase 5; Swiss-Prot: sp|Q9ZNW0|MOCS3_ARATH Adenylyltransferase and sulfurtransferase MOCS3; TrEMBL-Plants: tr|I1JJC5|I1JJC5_SOYBN Adenylyltransferase and sulfurtransferase MOCS3; Found in the gene: LotjaGi1g1v0025600
Domains
14
LotjaGi1g1v0025600.3
– Adenylyltransferase and sulfurtransferase MOCS3; TAIR: AT5G55130.1 co-factor for nitrate, reductase and xanthine dehydrogenase 5; Swiss-Prot: sp|Q9ZNW0|MOCS3_ARATH Adenylyltransferase and sulfurtransferase MOCS3; TrEMBL-Plants: tr|I1JJC5|I1JJC5_SOYBN Adenylyltransferase and sulfurtransferase MOCS3; Found in the gene: LotjaGi1g1v0025600
Domains
14
LotjaGi1g1v0095800.1
– Adenylyltransferase and sulfurtransferase MOCS3; TAIR: AT5G37530.1 NAD(P)-binding Rossmann-fold superfamily protein; Swiss-Prot: sp|P36101|TCD2_YEAST tRNA threonylcarbamoyladenosine dehydratase 2; TrEMBL-Plants: tr|K7M8D6|K7M8D6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0095800
Domains
12
LotjaGi1g1v0095800.2
– Adenylyltransferase and sulfurtransferase MOCS3; TAIR: AT5G37530.1 NAD(P)-binding Rossmann-fold superfamily protein; Swiss-Prot: sp|O13861|TCD_SCHPO tRNA threonylcarbamoyladenosine dehydratase; TrEMBL-Plants: tr|K7M8D6|K7M8D6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0095800
Domains
12
LotjaGi1g1v0116200.1
– Ubiquitin activating enzyme E1; TAIR: AT2G30110.1 ubiquitin-activating enzyme 1; Swiss-Prot: sp|P93028|UBE11_ARATH Ubiquitin-activating enzyme E1 1; TrEMBL-Plants: tr|K7KA83|K7KA83_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0116200
Domains
39
LotjaGi1g1v0116200.2
– Ubiquitin activating enzyme E1; TAIR: AT5G06460.1 ubiquitin activating enzyme 2; Swiss-Prot: sp|P92974|UBE12_ARATH Ubiquitin-activating enzyme E1 2; TrEMBL-Plants: tr|G7KEA9|G7KEA9_MEDTR Ubiquitin-activating enzyme E1 1; Found in the gene: LotjaGi1g1v0116200
Domains
39
LotjaGi1g1v0116200.3
– Ubiquitin activating enzyme E1; TAIR: AT2G30110.1 ubiquitin-activating enzyme 1; Swiss-Prot: sp|P93028|UBE11_ARATH Ubiquitin-activating enzyme E1 1; TrEMBL-Plants: tr|G7KEA8|G7KEA8_MEDTR Ubiquitin-activating enzyme E1 1; Found in the gene: LotjaGi1g1v0116200
Domains
38
LotjaGi1g1v0116200.4
– Ubiquitin activating enzyme E1; TAIR: AT2G30110.1 ubiquitin-activating enzyme 1; Swiss-Prot: sp|P93028|UBE11_ARATH Ubiquitin-activating enzyme E1 1; TrEMBL-Plants: tr|G7KEA8|G7KEA8_MEDTR Ubiquitin-activating enzyme E1 1; Found in the gene: LotjaGi1g1v0116200
Domains
38
LotjaGi1g1v0116200.5
– Ubiquitin activating enzyme E1; TAIR: AT2G30110.1 ubiquitin-activating enzyme 1; Swiss-Prot: sp|P93028|UBE11_ARATH Ubiquitin-activating enzyme E1 1; TrEMBL-Plants: tr|G7KEA8|G7KEA8_MEDTR Ubiquitin-activating enzyme E1 1; Found in the gene: LotjaGi1g1v0116200
Domains
38
LotjaGi1g1v0116200.6
– Ubiquitin activating enzyme E1; TAIR: AT2G30110.1 ubiquitin-activating enzyme 1; Swiss-Prot: sp|P93028|UBE11_ARATH Ubiquitin-activating enzyme E1 1; TrEMBL-Plants: tr|G7KEA9|G7KEA9_MEDTR Ubiquitin-activating enzyme E1 1; Found in the gene: LotjaGi1g1v0116200
Domains
39
LotjaGi1g1v0275000_LC.1
– Ubiquitin activating enzyme E1; TAIR: AT2G21470.1 SUMO-activating enzyme 2; Swiss-Prot: sp|Q9SJT1|SAE2_ARATH SUMO-activating enzyme subunit 2; TrEMBL-Plants: tr|V7ALR1|V7ALR1_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0275000_LC
Domains
8
LotjaGi1g1v0338800.1
– Ubiquitin-like modifier-activating enzyme 5; TAIR: AT1G05350.1 NAD(P)-binding Rossmann-fold superfamily protein; Swiss-Prot: sp|O23034|UBA5_ARATH Ubiquitin-like modifier-activating enzyme 5; TrEMBL-Plants: tr|I3S0U0|I3S0U0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0338800
Domains
11
LotjaGi3g1v0061900.1
– SUMO-activating enzyme 2; TAIR: AT2G21470.1 SUMO-activating enzyme 2; Swiss-Prot: sp|Q9SJT1|SAE2_ARATH SUMO-activating enzyme subunit 2; TrEMBL-Plants: tr|I1LVC3|I1LVC3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0061900
Domains
17
LotjaGi3g1v0061900.2
– SUMO-activating enzyme 2; TAIR: AT2G21470.1 SUMO-activating enzyme 2; Swiss-Prot: sp|Q9SJT1|SAE2_ARATH SUMO-activating enzyme subunit 2; TrEMBL-Plants: tr|I1LVC3|I1LVC3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0061900
Domains
16
LotjaGi3g1v0323700_LC.1
– Adenylyltransferase and sulfurtransferase; TAIR: AT2G21470.1 SUMO-activating enzyme 2; Swiss-Prot: sp|Q9SJT1|SAE2_ARATH SUMO-activating enzyme subunit 2; TrEMBL-Plants: tr|V7ALR1|V7ALR1_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0323700_LC
Domains
8
LotjaGi3g1v0466500.1
– NEDD8-activating enzyme E1 regulatory subunit; TAIR: AT1G05180.1 NAD(P)-binding Rossmann-fold superfamily protein; Swiss-Prot: sp|P42744|AXR1_ARATH NEDD8-activating enzyme E1 regulatory subunit AXR1; TrEMBL-Plants: tr|I3SW23|I3SW23_LOTJA NEDD8-activating enzyme E1 regulatory subunit; Found in the gene: LotjaGi3g1v0466500
Domains
10
LotjaGi3g1v0466500.2
– NEDD8-activating enzyme E1 regulatory subunit; TAIR: AT1G05180.1 NAD(P)-binding Rossmann-fold superfamily protein; Swiss-Prot: sp|P42744|AXR1_ARATH NEDD8-activating enzyme E1 regulatory subunit AXR1; TrEMBL-Plants: tr|I3SW23|I3SW23_LOTJA NEDD8-activating enzyme E1 regulatory subunit; Found in the gene: LotjaGi3g1v0466500
Domains
10
LotjaGi3g1v0466500.3
– NEDD8-activating enzyme E1 regulatory subunit; TAIR: AT1G05180.1 NAD(P)-binding Rossmann-fold superfamily protein; Swiss-Prot: sp|P42744|AXR1_ARATH NEDD8-activating enzyme E1 regulatory subunit AXR1; TrEMBL-Plants: tr|I3SW23|I3SW23_LOTJA NEDD8-activating enzyme E1 regulatory subunit; Found in the gene: LotjaGi3g1v0466500
Domains
5
LotjaGi3g1v0466500.4
– NEDD8-activating enzyme E1 regulatory subunit; TAIR: AT1G05180.1 NAD(P)-binding Rossmann-fold superfamily protein; Swiss-Prot: sp|P42744|AXR1_ARATH NEDD8-activating enzyme E1 regulatory subunit AXR1; TrEMBL-Plants: tr|I3SW23|I3SW23_LOTJA NEDD8-activating enzyme E1 regulatory subunit; Found in the gene: LotjaGi3g1v0466500
Domains
5
LotjaGi3g1v0547800.1
– Ubiquitin-like modifier-activating enzyme atg7; TAIR: AT5G45900.1 ThiF family protein; Swiss-Prot: sp|Q94CD5|ATG7_ARATH Ubiquitin-like modifier-activating enzyme atg7; TrEMBL-Plants: tr|A0A0B2RJ97|A0A0B2RJ97_GLYSO Ubiquitin-like modifier-activating enzyme atg7; Found in the gene: LotjaGi3g1v0547800
Domains
16
LotjaGi3g1v0547800.2
– Ubiquitin-like modifier-activating enzyme atg7; TAIR: AT5G45900.1 ThiF family protein; Swiss-Prot: sp|Q94CD5|ATG7_ARATH Ubiquitin-like modifier-activating enzyme atg7; TrEMBL-Plants: tr|A0A0B2RJ97|A0A0B2RJ97_GLYSO Ubiquitin-like modifier-activating enzyme atg7; Found in the gene: LotjaGi3g1v0547800
Domains
16
LotjaGi3g1v0547800.3
– Ubiquitin-like modifier-activating enzyme atg7; TAIR: AT5G45900.1 ThiF family protein; Swiss-Prot: sp|Q94CD5|ATG7_ARATH Ubiquitin-like modifier-activating enzyme atg7; TrEMBL-Plants: tr|A0A0B2RJ97|A0A0B2RJ97_GLYSO Ubiquitin-like modifier-activating enzyme atg7; Found in the gene: LotjaGi3g1v0547800
Domains
16
LotjaGi4g1v0069200.1
– SUMO-activating enzyme subunit 1; TAIR: AT4G24940.1 SUMO-activating enzyme 1A; Swiss-Prot: sp|Q8VY78|SAE1A_ARATH SUMO-activating enzyme subunit 1A; TrEMBL-Plants: tr|A0A1J7HZ69|A0A1J7HZ69_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0069200
Domains
8
LotjaGi4g1v0352900.1
– NEDD8-activating enzyme E1 catalytic subunit; TAIR: AT5G19180.1 E1 C-terminal related 1; Swiss-Prot: sp|O65041|UBA3_ARATH NEDD8-activating enzyme E1 catalytic subunit; TrEMBL-Plants: tr|I1KNA2|I1KNA2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0352900
Domains
17
LotjaGi4g1v0418200.1
– SUMO-activating enzyme subunit 1; TAIR: AT4G24940.1 SUMO-activating enzyme 1A; Swiss-Prot: sp|Q8VY78|SAE1A_ARATH SUMO-activating enzyme subunit 1A; TrEMBL-Plants: tr|I3SJS2|I3SJS2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0418200
Domains
7
LotjaGi6g1v0126000.1
– Ubiquitin activating enzyme E1; TAIR: AT2G30110.1 ubiquitin-activating enzyme 1; Swiss-Prot: sp|P93028|UBE11_ARATH Ubiquitin-activating enzyme E1 1; TrEMBL-Plants: tr|A0A0L9VCA7|A0A0L9VCA7_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0126000
Domains
36
LotjaGi6g1v0126000.2
– Ubiquitin activating enzyme E1; TAIR: AT2G30110.1 ubiquitin-activating enzyme 1; Swiss-Prot: sp|P93028|UBE11_ARATH Ubiquitin-activating enzyme E1 1; TrEMBL-Plants: tr|I1MZW3|I1MZW3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0126000
Domains
35
LotjaGi6g1v0126000.3
– Ubiquitin activating enzyme E1; TAIR: AT2G30110.1 ubiquitin-activating enzyme 1; Swiss-Prot: sp|P93028|UBE11_ARATH Ubiquitin-activating enzyme E1 1; TrEMBL-Plants: tr|A0A0L9VCA7|A0A0L9VCA7_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0126000
Domains
36
LotjaGi6g1v0126000.4
– Ubiquitin activating enzyme E1; TAIR: AT2G30110.1 ubiquitin-activating enzyme 1; Swiss-Prot: sp|P93028|UBE11_ARATH Ubiquitin-activating enzyme E1 1; TrEMBL-Plants: tr|I1MZW3|I1MZW3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0126000
Domains
35

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd01491 CDD 1 3.33