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IPR039010 is a Synaptotagmin, SMP domain.
<p>SMP is a proposed lipid-binding module, ie a synaptotagmin-like mitochondrial-lipid-binding domain found in eukaryotes. The SMP domain has a β-barrel structure like protein modules in the tubular-lipid-binding (TULIP) superfamily. It dimerises to form an approximately 90-Angstrom-long cylinder traversed by a channel lined entirely with hydrophobic residues. The following two C2 domains then form arched structures flexibly linked to the SMP domain. The SMP domain is a lipid-binding domain that links the ER with other lipid bilayer-membranes within the cell [[cite:PUB00075878]].</p> <p>This entry represents the SMP domain found in plant synaptotagmins [[cite:PUB00088727]] and extended synaptotagmins from metazoa. The extended synaptotagmins transport glycerolipids between the two bilayers via their lipid-harboring SMP domains and Ca2 + regulates their membrane tethering and lipid transport function [[cite:PUB00087563]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Synaptotagmin-5; TAIR: AT5G11100.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|A0JJX5|SYT4_ARATH Synaptotagmin-4; TrEMBL-Plants: tr|A0A0R0JHJ4|A0A0R0JHJ4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0381800 | 19 | ||
| – | Synaptotagmin-5; TAIR: AT5G11100.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|A0JJX5|SYT4_ARATH Synaptotagmin-4; TrEMBL-Plants: tr|A0A0R0JHJ4|A0A0R0JHJ4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0381800 | 19 | ||
| – | Calcium lipid binding protein, putative; TAIR: AT3G61050.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|A0JJX5|SYT4_ARATH Synaptotagmin-4; TrEMBL-Plants: tr|I1L6S3|I1L6S3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0465600 | 24 | ||
| – | Calcium lipid binding protein, putative; TAIR: AT3G61050.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|A0JJX5|SYT4_ARATH Synaptotagmin-4; TrEMBL-Plants: tr|I1L6S3|I1L6S3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0465600 | 24 | ||
| – | Extended synaptotagmin-2; TAIR: AT3G61050.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|Q8L706|SYT5_ARATH Synaptotagmin-5; TrEMBL-Plants: tr|G7L1E7|G7L1E7_MEDTR C2 calcium/lipid-binding and GRAM domain protein; Found in the gene: LotjaGi1g1v0465600 | 13 | ||
| – | Synaptotagmin-5; TAIR: AT3G61050.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|A0JJX5|SYT4_ARATH Synaptotagmin-4; TrEMBL-Plants: tr|A0A0B2P651|A0A0B2P651_GLYSO Extended synaptotagmin-2; Found in the gene: LotjaGi1g1v0465600 | 21 | ||
| – | Calcium lipid binding protein, putative; TAIR: AT3G61050.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|A0JJX5|SYT4_ARATH Synaptotagmin-4; TrEMBL-Plants: tr|I1L6S3|I1L6S3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0465600 | 24 | ||
| – | Synaptotagmin-1; TAIR: AT1G20080.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|B6ETT4|SYT2_ARATH Synaptotagmin-2; TrEMBL-Plants: tr|A0A151TMN0|A0A151TMN0_CAJCA Extended synaptotagmin-2-B; Found in the gene: LotjaGi1g1v0559400 | 19 | ||
| – | Synaptotagmin, putative; TAIR: AT1G20080.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|B6ETT4|SYT2_ARATH Synaptotagmin-2; TrEMBL-Plants: tr|A0A1J7IIF6|A0A1J7IIF6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0559400 | 15 | ||
| – | Calcium lipid binding protein, putative; TAIR: AT3G61050.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|A0JJX5|SYT4_ARATH Synaptotagmin-4; TrEMBL-Plants: tr|K7KCB9|K7KCB9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0430200 | 22 | ||
| – | Synaptotagmin-5; TAIR: AT3G61050.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|A0JJX5|SYT4_ARATH Synaptotagmin-4; TrEMBL-Plants: tr|K7KCB9|K7KCB9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0430200 | 19 | ||
| – | Calcium lipid binding protein, putative; TAIR: AT3G61050.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|A0JJX5|SYT4_ARATH Synaptotagmin-4; TrEMBL-Plants: tr|K7KCB9|K7KCB9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0430200 | 22 | ||
| – | Calcium lipid binding protein, putative; TAIR: AT3G61050.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|A0JJX5|SYT4_ARATH Synaptotagmin-4; TrEMBL-Plants: tr|I1JKI9|I1JKI9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0430200 | 20 | ||
| – | Synaptotagmin-1; TAIR: AT2G20990.1 synaptotagmin A; Swiss-Prot: sp|Q9SKR2|SYT1_ARATH Synaptotagmin-1; TrEMBL-Plants: tr|K7LST9|K7LST9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0521200 | 19 | ||
| – | Calcium lipid binding protein, putative; TAIR: AT2G20990.1 synaptotagmin A; Swiss-Prot: sp|Q9SKR2|SYT1_ARATH Synaptotagmin-1; TrEMBL-Plants: tr|I1LJ17|I1LJ17_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0521200 | 19 | ||
| – | Calcium-dependent lipid-binding (CaLB domain) family protein; TAIR: AT2G20990.1 synaptotagmin A; Swiss-Prot: sp|Q9SKR2|SYT1_ARATH Synaptotagmin-1; TrEMBL-Plants: tr|I1LJ17|I1LJ17_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0521200 | 19 | ||
| – | Synaptotagmin-1; TAIR: AT2G20990.1 synaptotagmin A; Swiss-Prot: sp|Q9SKR2|SYT1_ARATH Synaptotagmin-1; TrEMBL-Plants: tr|K7LST9|K7LST9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0521200 | 15 | ||
| – | Synaptotagmin, putative; TAIR: AT1G20080.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|B6ETT4|SYT2_ARATH Synaptotagmin-2; TrEMBL-Plants: tr|I1LPS0|I1LPS0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0521200 | 15 | ||
| – | Synaptotagmin-5; TAIR: AT1G05500.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|Q8L706|SYT5_ARATH Synaptotagmin-5; TrEMBL-Plants: tr|A0A0B2Q5D1|A0A0B2Q5D1_GLYSO Extended synaptotagmin-3; Found in the gene: LotjaGi4g1v0277600 | 19 | ||
| – | Synaptotagmin-1; TAIR: AT1G20080.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|B6ETT4|SYT2_ARATH Synaptotagmin-2; TrEMBL-Plants: tr|A0A151UDU8|A0A151UDU8_CAJCA Extended synaptotagmin-2; Found in the gene: LotjaGi5g1v0004700 | 20 | ||
| – | Synaptotagmin-1; TAIR: AT1G20080.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|B6ETT4|SYT2_ARATH Synaptotagmin-2; TrEMBL-Plants: tr|A0A151UDU8|A0A151UDU8_CAJCA Extended synaptotagmin-2; Found in the gene: LotjaGi5g1v0004700 | 20 | ||
| – | Synaptotagmin-1; TAIR: AT2G20990.1 synaptotagmin A; Swiss-Prot: sp|Q9SKR2|SYT1_ARATH Synaptotagmin-1; TrEMBL-Plants: tr|A0A151UDU8|A0A151UDU8_CAJCA Extended synaptotagmin-2; Found in the gene: LotjaGi5g1v0004700 | 16 | ||
| – | Calcium lipid binding protein, putative; TAIR: AT5G04220.3 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|Q7XA06|SYT3_ARATH Synaptotagmin-3; TrEMBL-Plants: tr|A0A151SED0|A0A151SED0_CAJCA Extended synaptotagmin-2; Found in the gene: LotjaGi5g1v0273300 | 15 | ||
| – | Synaptotagmin-2; TAIR: AT5G04220.2 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|Q7XA06|SYT3_ARATH Synaptotagmin-3; TrEMBL-Plants: tr|I1LD00|I1LD00_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0273300 | 19 | ||
| – | Calcium-dependent lipid-binding (CaLB domain) family protein; TAIR: AT5G04220.2 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|Q7XA06|SYT3_ARATH Synaptotagmin-3; TrEMBL-Plants: tr|I1LD00|I1LD00_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0273300 | 19 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00030 | CDD | 1 | 4.00 |