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IPR002610 is a Peptidase S54, RHOMBOID-like.
<p>This group of proteins contain serine peptidases belonging to the MEROPS peptidase family S54 (Rhomboid, clan ST). They are integral membrane proteins related to the Drosophila melanogaster (Fruit fly) rhomboid protein [swissprot:P20350]. Members of this family are found in bacteria, archaea, and eukaryotes, mainly plant and fungi.</p> <p>Plant rhomboid-like proteins are rhomboid-type serine proteases that catalyse intramembrane proteolysis [[cite:PUB00152817]]. This entry also includes some inactive homologues, such as Inactive RHOMBOID-like protein 8 from Arabidopsis (also known as KOM and KOMPEITO), which is essential for the meiosis stage-specific callose accumulation and pollen exine formation [[cite:PUB00152819]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Serine-type endopeptidase activity | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). | ||
| Biological process | Proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. | ||
| Cellular component | Integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: inactive rhomboid protein 1-like [Glycine max] gi|356504274|ref|XP_003520922.1| | 11 | ||
| – | PREDICTED: inactive rhomboid protein 1-like [Cicer arietinum] gi|502175388|ref|XP_004515720.1| | 11 | ||
| – | PREDICTED: inactive rhomboid protein 1-like [Glycine max] gi|356557429|ref|XP_003547018.1| | 12 | ||
| – | Chondroitin sulfate proteoglycan 5 [Chelonia mydas] gi|465962020|gb|EMP29585.1| | 10 | ||
| – | Rhomboid-related intramembrane serine protease-like protein [Arabidopsis thaliana] gi|15240938|ref|NP_198667.1| | 7 | ||
| – | PREDICTED: rhomboid protease GluP-like [Solanum lycopersicum] gi|460373127|ref|XP_004232374.1| | 11 | ||
| – | Rhomboid family protein (ISS) [Medicago truncatula] gi|357436521|ref|XP_003588536.1| | 11 | ||
| – | Rhomboid family protein [Arabidopsis lyrata subsp]. lyrata] gi|297812787|ref|XP_002874277.1| | 11 | ||
| – | PREDICTED: rhomboid protein 1, mitochondrial [Vitis vinifera] gi|225456573|ref|XP_002265768.1| | 12 | ||
| – | PREDICTED: rhomboid protein 1, mitochondrial [Vitis vinifera] gi|225456573|ref|XP_002265768.1| | 11 | ||
| – | PREDICTED: inactive rhomboid protein 1-like isoform 1 [Glycine max] gi|356575933|ref|XP_003556090.1| | 12 | ||
| – | Rhomboid protease gluP [Medicago truncatula] gi|357452411|ref|XP_003596482.1| | 11 | ||
| – | Rhomboid-like protein; TAIR: AT1G77860.2 Rhomboid-related intramembrane serine protease family protein; Swiss-Prot: sp|F4I8K2|RBL8_ARATH RHOMBOID-like protein 8; TrEMBL-Plants: tr|A0A1J7GBZ3|A0A1J7GBZ3_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0248700 | 13 | ||
| – | Rhomboid-like protein; TAIR: AT2G29050.1 RHOMBOID-like 1; Swiss-Prot: sp|Q0WQX7|RBL1_ARATH RHOMBOID-like protein 1; TrEMBL-Plants: tr|K7M3E7|K7M3E7_SOYBN Rhomboid-like protein; Found in the gene: LotjaGi1g1v0576100 | 13 | ||
| – | Rhomboid-like protein; TAIR: AT2G29050.1 RHOMBOID-like 1; Swiss-Prot: sp|Q0WQX7|RBL1_ARATH RHOMBOID-like protein 1; TrEMBL-Plants: tr|A0A151SUQ7|A0A151SUQ7_CAJCA Rhomboid-like protein; Found in the gene: LotjaGi1g1v0576100 | 12 | ||
| – | Rhomboid-like protein; TAIR: AT1G63120.1 RHOMBOID-like 2; Swiss-Prot: sp|Q9CAN1|RBL2_ARATH RHOMBOID-like protein 2; TrEMBL-Plants: tr|A0A151U6I6|A0A151U6I6_CAJCA Rhomboid-like protein; Found in the gene: LotjaGi2g1v0147200 | 12 | ||
| – | Rhomboid-like protein; TAIR: AT1G52580.1 RHOMBOID-like protein 5; Swiss-Prot: sp|Q9SSR0|RBL5_ARATH RHOMBOID-like protein 5; TrEMBL-Plants: tr|A0A151SXT1|A0A151SXT1_CAJCA Putative polygalacturonase family; Found in the gene: LotjaGi3g1v0009700 | 12 | ||
| – | Rhomboid-like protein; TAIR: AT2G29050.1 RHOMBOID-like 1; Swiss-Prot: sp|Q0WQX7|RBL1_ARATH RHOMBOID-like protein 1; TrEMBL-Plants: tr|I1JLP8|I1JLP8_SOYBN Rhomboid-like protein; Found in the gene: LotjaGi3g1v0225800 | 12 | ||
| – | Rhomboid-like protein; TAIR: AT1G63120.1 RHOMBOID-like 2; Swiss-Prot: sp|Q9CAN1|RBL2_ARATH RHOMBOID-like protein 2; TrEMBL-Plants: tr|V7BC17|V7BC17_PHAVU Rhomboid-like protein; Found in the gene: LotjaGi5g1v0303600 | 13 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 5.26 |