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IPR002792 is a TRAM domain.
<p>The TRAM (after TRM2 and miaB) domain is a 60-70-residue-long module that is found in: <ul> <li>Two distinct classes of tRNA-modifying enzymes, namely uridine methylases of the TRM2 family and enzymes of the miaB family that are involved in 2- methylthioadenine formation</li> <li>In several other proteins associated with the translation machinery</li> <li>In a family of small uncharacterised archaeal proteins that are predicted to have a role in the regulation of tRNA modification and/or translation</li> </ul> The TRAM domain can be found alone or in association with other domains, such as the catalytic biotin/lipoate synthetase-like domain, the RNA methylase domain, the ribosomal S2 domain and the eIF2-beta domain. The TRAM domain is predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets [[cite:PUB00009729]]. Secondary structure prediction indicates that the TRAM domain adopts a simple β-barrel fold. The conservation pattern of the TRAM domain consists primarily of small and hydrophobic residues that correspond to five β-strands in the predicted secondary structure [[cite:PUB00009729]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: CDK5RAP1-like protein-like [Glycine max] gi|356540793|ref|XP_003538869.1| | 33 | ||
– | PREDICTED: CDKAL1-like protein-like [Glycine max] gi|356542899|ref|XP_003539902.1| | 29 | ||
– | TRNA-2-methylthio-N(6)-dimethylallyladenosine synthase; TAIR: AT4G36390.1 Methylthiotransferase; Swiss-Prot: sp|Q8H0V1|CK5P1_ARATH CDK5RAP1-like protein; TrEMBL-Plants: tr|G7KGB3|G7KGB3_MEDTR Radical SAM methylthiotransferase, MiaB/RimO family protein; Found in the gene: LotjaGi2g1v0385400 | 28 | ||
– | TRNA-2-methylthio-N(6)-dimethylallyladenosine synthase; TAIR: AT4G36390.1 Methylthiotransferase; Swiss-Prot: sp|Q2R1U4|CK5P1_ORYSJ CDK5RAP1-like protein; TrEMBL-Plants: tr|K7LNH5|K7LNH5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0385400 | 26 | ||
– | TRNA-2-methylthio-N(6)-dimethylallyladenosine synthase; TAIR: AT4G36390.1 Methylthiotransferase; Swiss-Prot: sp|Q2R1U4|CK5P1_ORYSJ CDK5RAP1-like protein; TrEMBL-Plants: tr|K7LNH5|K7LNH5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0385400 | 26 | ||
– | TRNA-2-methylthio-N(6)-dimethylallyladenosine synthase; TAIR: AT4G36390.1 Methylthiotransferase; Swiss-Prot: sp|Q2R1U4|CK5P1_ORYSJ CDK5RAP1-like protein; TrEMBL-Plants: tr|K7LNH5|K7LNH5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0385400 | 26 | ||
– | 23S rRNA (Uracil-5-)-methyltransferase; TAIR: AT3G21300.1 RNA methyltransferase family protein; Swiss-Prot: sp|Q8KGF9|Y009_CHLTE Uncharacterized RNA methyltransferase CT0009; TrEMBL-Plants: tr|G7IHW5|G7IHW5_MEDTR 23S rRNA (Uracil-5)-methyltransferase RumA; Found in the gene: LotjaGi3g1v0022800 | 18 | ||
– | 23S rRNA (Uracil-5-)-methyltransferase; TAIR: AT3G21300.1 RNA methyltransferase family protein; Swiss-Prot: sp|Q8KGF9|Y009_CHLTE Uncharacterized RNA methyltransferase CT0009; TrEMBL-Plants: tr|G7IHW5|G7IHW5_MEDTR 23S rRNA (Uracil-5)-methyltransferase RumA; Found in the gene: LotjaGi3g1v0022800 | 18 | ||
– | TRNA-2-methylthio-N(6)-dimethylallyladenosine synthase; TAIR: AT1G72090.1 Methylthiotransferase; Swiss-Prot: sp|Q6P4Y0|CDKAL_XENTR Threonylcarbamoyladenosine tRNA methylthiotransferase; TrEMBL-Plants: tr|I1LNN6|I1LNN6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0556600 | 29 | ||
– | TRNA-2-methylthio-N(6)-dimethylallyladenosine synthase; TAIR: AT1G72090.1 Methylthiotransferase; Swiss-Prot: sp|Q6NS26|CDKAL_XENLA Threonylcarbamoyladenosine tRNA methylthiotransferase; TrEMBL-Plants: tr|I1LNN6|I1LNN6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0556600 | 29 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd01335 | CDD | 1 | 10.00 |