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IPR018359 is a Bromodomain, conserved site.
<p>Bromodomains are found in a variety of mammalian, invertebrate and yeast DNA-binding proteins [[cite:PUB00004405]]. Bromodomains are highly conserved α-helical motifs that can specifically interact with acetylated lysine residues on histone tails [[cite:PUB00005462], [cite:PUB00097275]]. In some proteins, the classical bromodomain has diverged to such an extent that parts of the region are either missing or contain an insertion (e.g., mammalian protein HRX, Caenorhabditis elegans hypothetical protein ZK783.4, yeast protein YTA7). The bromodomain may occur as a single copy, or in duplicate.</p> <p>This domain is present in proteins involved in a wide range of functions such as acetylating histones, remodeling chromatin, and recruiting other factors necessary for transcription, thus playing a critical role in the regulation of transcription [[cite:PUB00097276]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Bromodomain-containing protein [Medicago truncatula] gi|357494567|ref|XP_003617572.1| | 14 | ||
| – | Bromodomain-containing protein [Ricinus communis] gi|255539242|ref|XP_002510686.1| | 14 | ||
| – | PREDICTED: histone acetyltransferase GCN5-like [Cicer arietinum] gi|502109822|ref|XP_004493735.1| | 19 | ||
| – | PREDICTED: transcription initiation factor TFIID subunit 1-A-like [Glycine max] gi|356529777|ref|XP_003533464.1| | 24 | ||
| – | PREDICTED: transcription initiation factor TFIID subunit 1-A-like [Glycine max] gi|356529777|ref|XP_003533464.1| | 28 | ||
| – | PREDICTED: transcription initiation factor TFIID subunit 1-A-like isoform X3 [Cicer arietinum] gi|502162054|ref|XP_004512374.1| | 17 | ||
| – | Bromodomain-containing protein [Medicago truncatula] gi|357459703|ref|XP_003600132.1| | 13 | ||
| – | Bromodomain-containing protein [Medicago truncatula] gi|357445295|ref|XP_003592925.1| | 14 | ||
| – | Bromodomain-containing protein, putative; TAIR: AT5G55040.1 DNA-binding bromodomain-containing protein; Swiss-Prot: sp|Q9ULD4|BRPF3_HUMAN Bromodomain and PHD finger-containing protein 3; TrEMBL-Plants: tr|A0A0L9UUY7|A0A0L9UUY7_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0027400 | 15 | ||
| – | Bromodomain-containing protein; TAIR: AT1G20670.1 DNA-binding bromodomain-containing protein; Swiss-Prot: sp|O95696|BRD1_HUMAN Bromodomain-containing protein 1; TrEMBL-Plants: tr|K7KHM0|K7KHM0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0566700 | 15 | ||
| – | Histone acetyltransferase GCN5; TAIR: AT3G54610.1 histone acetyltransferase of the GNAT family 1; Swiss-Prot: sp|Q9AR19|GCN5_ARATH Histone acetyltransferase GCN5; TrEMBL-Plants: tr|I1JNY5|I1JNY5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0714400 | 22 | ||
| – | Histone acetyltransferase GCN5; TAIR: AT3G54610.1 histone acetyltransferase of the GNAT family 1; Swiss-Prot: sp|Q9AR19|GCN5_ARATH Histone acetyltransferase GCN5; TrEMBL-Plants: tr|I1JNY5|I1JNY5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0714400 | 22 | ||
| – | Transcription initiation factor tfiid subunit 1; TAIR: AT1G32750.1 HAC13 protein (HAC13); Swiss-Prot: sp|Q8LRK9|TAF1_ARATH Transcription initiation factor TFIID subunit 1; TrEMBL-Plants: tr|I1L578|I1L578_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0344200 | 30 | ||
| – | Transcription initiation factor tfiid subunit 1; TAIR: AT1G32750.1 HAC13 protein (HAC13); Swiss-Prot: sp|Q8LRK9|TAF1_ARATH Transcription initiation factor TFIID subunit 1; TrEMBL-Plants: tr|I1L578|I1L578_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0344200 | 30 | ||
| – | Transcription initiation factor tfiid subunit 1; TAIR: AT1G32750.1 HAC13 protein (HAC13); Swiss-Prot: sp|Q8LRK9|TAF1_ARATH Transcription initiation factor TFIID subunit 1; TrEMBL-Plants: tr|I1L578|I1L578_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0344200 | 32 | ||
| – | Transcription initiation factor tfiid subunit 1; TAIR: AT1G32750.1 HAC13 protein (HAC13); Swiss-Prot: sp|Q8LRK9|TAF1_ARATH Transcription initiation factor TFIID subunit 1; TrEMBL-Plants: tr|I1L578|I1L578_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0344200 | 30 | ||
| – | Transcription initiation factor tfiid subunit 1; TAIR: AT1G32750.1 HAC13 protein (HAC13); Swiss-Prot: sp|Q8LRK9|TAF1_ARATH Transcription initiation factor TFIID subunit 1; TrEMBL-Plants: tr|I1L578|I1L578_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0344200 | 32 | ||
| – | Transcription initiation factor tfiid subunit 1; TAIR: AT1G32750.1 HAC13 protein (HAC13); Swiss-Prot: sp|Q8LRK9|TAF1_ARATH Transcription initiation factor TFIID subunit 1; TrEMBL-Plants: tr|K7LF91|K7LF91_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0344200 | 28 | ||
| – | Transcription initiation factor tfiid subunit 1; TAIR: AT1G32750.1 HAC13 protein (HAC13); Swiss-Prot: sp|Q8LRK9|TAF1_ARATH Transcription initiation factor TFIID subunit 1; TrEMBL-Plants: tr|K7LF91|K7LF91_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0344200 | 28 | ||
| – | Bromodomain-containing protein; TAIR: AT5G55040.1 DNA-binding bromodomain-containing protein; Swiss-Prot: sp|Q9ULD4|BRPF3_HUMAN Bromodomain and PHD finger-containing protein 3; TrEMBL-Plants: tr|A0A0R0F849|A0A0R0F849_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0158100 | 15 | ||
| – | Bromodomain; TAIR: AT1G58025.3 DNA-binding bromodomain-containing protein; Swiss-Prot: sp|Q6DFF2|BRD4B_XENLA Bromodomain-containing protein 4B; TrEMBL-Plants: tr|A0A151T839|A0A151T839_CAJCA Bromodomain-containing protein 4; Found in the gene: LotjaGi6g1v0364000 | 13 | ||
| – | Bromodomain; TAIR: AT1G58025.3 DNA-binding bromodomain-containing protein; Swiss-Prot: sp|Q6DFF2|BRD4B_XENLA Bromodomain-containing protein 4B; TrEMBL-Plants: tr|A0A151T839|A0A151T839_CAJCA Bromodomain-containing protein 4; Found in the gene: LotjaGi6g1v0364000 | 13 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 4.55 |