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PF01068

Description

ATP dependent DNA ligase domain

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function DNA ligase (ATP) activity Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m).
Molecular function ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
Biological process DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
Biological process DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.

Associated Lotus transcripts 8

Transcript Name Description Predicted domains Domain count
PREDICTED: DNA ligase 1-like, partial [Cicer arietinum] gi|502106786|ref|XP_004493055.1| 18
PREDICTED: DNA ligase 1-like isoform X1 [Cicer arietinum] gi|502145536|ref|XP_004506069.1| 26
PREDICTED: DNA ligase 4-like [Cicer arietinum] gi|502085757|ref|XP_004487997.1| 13
DNA ligase; TAIR: AT1G66730.1 DNA LIGASE 6; Swiss-Prot: sp|F4HPZ9|LIG6_ARATH DNA ligase 6; TrEMBL-Plants: tr|G7KV95|G7KV95_MEDTR DNA ligase; Found in the gene: LotjaGi1g1v0545100 31
DNA ligase; TAIR: AT1G66730.1 DNA LIGASE 6; Swiss-Prot: sp|F4HPZ9|LIG6_ARATH DNA ligase 6; TrEMBL-Plants: tr|A0A0L9TDF0|A0A0L9TDF0_PHAAN DNA ligase; Found in the gene: LotjaGi1g1v0545100 34
DNA ligase; TAIR: AT1G08130.1 DNA ligase 1; Swiss-Prot: sp|Q42572|DNLI1_ARATH DNA ligase 1; TrEMBL-Plants: tr|A0A072UVT2|A0A072UVT2_MEDTR DNA ligase; Found in the gene: LotjaGi3g1v0485100 27
DNA ligase; TAIR: AT5G57160.2 DNA ligase IV; Swiss-Prot: sp|Q9LL84|DNLI4_ARATH DNA ligase 4; TrEMBL-Plants: tr|K7MBU8|K7MBU8_SOYBN DNA ligase; Found in the gene: LotjaGi6g1v0235200 26
DNA ligase; TAIR: AT5G57160.1 DNA ligase IV; Swiss-Prot: sp|Q9LL84|DNLI4_ARATH DNA ligase 4; TrEMBL-Plants: tr|K7MBU8|K7MBU8_SOYBN DNA ligase; Found in the gene: LotjaGi6g1v0235200 36

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 12.50