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IPR007641 is a RNA polymerase Rpb2, domain 7.
<p>RNA polymerases catalyse the DNA-dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial and chloroplast polymerases). Rpb2 is the second largest subunit of the RNA polymerase. This domain comprised of the structural domains anchor and clamp. The clamp region (C-terminal) contains a zinc-binding motif. The clamp region is named due to its interaction with the clamp domain found in Rpb1. The domain also contains a region termed switch 4. The switches within the polymerase are thought to signal different stages of transcription [[cite:PUB00008731]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). | ||
| Molecular function | DNA-directed 5'-3' RNA polymerase activity | Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. | ||
| Biological process | Transcription, DNA-templated | The cellular synthesis of RNA on a template of DNA. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | RNA polymerase beta subunit [Lotus japonicus] gi|13518436|ref|NP_084796.1| | 16 | ||
| – | DNA-directed RNA polymerase III subunit RPC2 [Medicago truncatula] gi|357514369|ref|XP_003627473.1| | 6 | ||
| – | DNA-directed RNA polymerase III subunit RPC2 [Medicago truncatula] gi|357514369|ref|XP_003627473.1| | 6 | ||
| – | DNA-directed RNA polymerase subunit beta [Medicago truncatula] gi|357466021|ref|XP_003603295.1| | 14 | ||
| – | DNA-directed RNA polymerase III subunit RPC2 [Medicago truncatula] gi|357514369|ref|XP_003627473.1| | 9 | ||
| – | PREDICTED: DNA-directed RNA polymerase I subunit RPA2-like [Glycine max] gi|356548837|ref|XP_003542805.1| | 23 | ||
| – | DNA-directed RNA polymerase III subunit RPC2 [Medicago truncatula] gi|357514369|ref|XP_003627473.1| | 6 | ||
| – | RNA polymerase beta subunit [Lotus japonicus] gi|13518436|ref|NP_084796.1| | 16 | ||
| – | DNA-directed RNA polymerase subunit beta; TAIR: AT3G23780.1 nuclear RNA polymerase D2A; Swiss-Prot: sp|Q9LK40|NRPD2_ARATH DNA-directed RNA polymerases IV and V subunit 2; TrEMBL-Plants: tr|A0A0B2RBE2|A0A0B2RBE2_GLYSO DNA-directed RNA polymerase subunit beta; Found in the gene: LotjaGi1g1v0377700 | 29 | ||
| – | DNA-directed RNA polymerase subunit beta; TAIR: AT3G23780.1 nuclear RNA polymerase D2A; Swiss-Prot: sp|Q9LK40|NRPD2_ARATH DNA-directed RNA polymerases IV and V subunit 2; TrEMBL-Plants: tr|G7J9U6|G7J9U6_MEDTR DNA-directed RNA polymerase subunit beta; Found in the gene: LotjaGi1g1v0377700 | 11 | ||
| – | DNA-directed RNA polymerase subunit beta; TAIR: AT5G45140.1 nuclear RNA polymerase C2; Swiss-Prot: sp|F4KD38|NRPC2_ARATH DNA-directed RNA polymerase III subunit 2; TrEMBL-Plants: tr|K7L1D3|K7L1D3_SOYBN DNA-directed RNA polymerase subunit beta; Found in the gene: LotjaGi3g1v0300900_LC | 26 | ||
| – | DNA-directed RNA polymerase subunit beta; TAIR: AT1G29940.1 nuclear RNA polymerase A2; Swiss-Prot: sp|F4I366|NRPA2_ARATH DNA-directed RNA polymerase I subunit 2; TrEMBL-Plants: tr|I1M0N3|I1M0N3_SOYBN DNA-directed RNA polymerase subunit beta; Found in the gene: LotjaGi3g1v0315900 | 28 | ||
| – | DNA-directed RNA polymerase subunit beta; TAIR: AT1G29940.1 nuclear RNA polymerase A2; Swiss-Prot: sp|F4I366|NRPA2_ARATH DNA-directed RNA polymerase I subunit 2; TrEMBL-Plants: tr|A0A0R0GQW5|A0A0R0GQW5_SOYBN DNA-directed RNA polymerase subunit beta; Found in the gene: LotjaGi3g1v0315900 | 28 | ||
| – | DNA-directed RNA polymerase subunit beta; TAIR: ATCG00190.1 RNA polymerase subunit beta (ChrC); Swiss-Prot: sp|Q9BBS9|RPOB_LOTJA DNA-directed RNA polymerase subunit beta; TrEMBL-Plants: tr|A0A1C7D303|A0A1C7D303_9FABA DNA-directed RNA polymerase subunit beta; Found in the gene: LotjaGi5g1v0143500_LC | 11 | ||
| – | DNA-directed RNA polymerase subunit beta; TAIR: ATCG00190.1 RNA polymerase subunit beta (ChrC); Swiss-Prot: sp|Q9BBS9|RPOB_LOTJA DNA-directed RNA polymerase subunit beta; TrEMBL-Plants: tr|A0A1C7D4C0|A0A1C7D4C0_ROBPS DNA-directed RNA polymerase subunit beta; Found in the gene: LotjaGi5g1v0143500_LC | 11 | ||
| – | DNA-directed RNA polymerase subunit beta; TAIR: AT5G45140.1 nuclear RNA polymerase C2; Swiss-Prot: sp|F4KD38|NRPC2_ARATH DNA-directed RNA polymerase III subunit 2; TrEMBL-Plants: tr|K7L1D3|K7L1D3_SOYBN DNA-directed RNA polymerase subunit beta; Found in the gene: LotjaGi5g1v0334100 | 30 | ||
| – | DNA-directed RNA polymerase subunit beta; TAIR: AT4G21710.1 DNA-directed RNA polymerase family protein; Swiss-Prot: sp|Q42877|RPB2_SOLLC DNA-directed RNA polymerase II subunit RPB2; TrEMBL-Plants: tr|V7BQ99|V7BQ99_PHAVU DNA-directed RNA polymerase subunit beta; Found in the gene: LotjaGi6g1v0332200 | 31 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 5.88 |