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IPR016072

Source: InterPro

Description

IPR016072 is a SKP1 component, dimerisation.

<p>SKP1 (together with SKP2) was identified as an essential component of the cyclin A-CDK2 S phase kinase complex [[cite:PUB00005233]]. It was found to bind several F-box containing proteins (e.g., Cdc4, Skp2, cyclin F) and to be involved in the ubiquitin protein degradation pathway. A yeast homologue of SKP1 (P52286) was identified in the centromere bound kinetochore complex [[cite:PUB00006069]] and is also involved in the ubiquitin pathway [[cite:PUB00006072]]. In Dictyostelium discoideum (Slime mold) FP21 was shown to be glycosylated in the cytosol and has homology to SKP1 [[cite:PUB00006070]].</p> <p>This entry represents a dimerisation domain found at the C-terminal of SKP1 proteins [[cite:PUB00010628]], as well as in subunit D of the centromere DNA-binding protein complex Cbf3 [[cite:PUB00029039]]. This domain is multi-helical in structure, and consists of an interlocked herterodimer in F-box proteins.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0006511
Biological process Ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
Subterm of

Associated Lotus transcripts 39

Transcript Name Description Predicted domains Domain count
Lj0g3v0079709.1
– PREDICTED: SKP1-like protein 14-like [Cicer arietinum] gi|502088225|ref|XP_004488771.1|
Domains
14
Lj0g3v0106769.1
– PREDICTED: SKP1-like protein 1A-like [Glycine max] gi|356496612|ref|XP_003517160.1|
Domains
11
Lj0g3v0259179.1
– PREDICTED: SKP1-like protein 1A [Vitis vinifera] gi|225428047|ref|XP_002279232.1|
Domains
7
Lj0g3v0261809.1
– PREDICTED: SKP1-like protein 14-like [Cicer arietinum] gi|502088225|ref|XP_004488771.1|
Domains
14
Lj0g3v0273719.1
– PREDICTED: ethylene-responsive transcription factor 5-like [Glycine max] gi|356541103|ref|XP_003539022.1|
Domains
20
Lj0g3v0349889.1
– PREDICTED: SKP1-like protein 14-like [Cicer arietinum] gi|502088225|ref|XP_004488771.1|
Domains
14
Lj1g3v2671420.2
– PREDICTED: SKP1-like protein 21-like [Glycine max] gi|356531993|ref|XP_003534559.1|
Domains
12
Lj1g3v2671420.4
– SKP1 component [Medicago truncatula] gi|124359727|gb|ABD32817.2|
Domains
14
Lj2g3v0344980.1
– PREDICTED: SKP1-like protein 21-like [Glycine max] gi|356520400|ref|XP_003528850.1|
Domains
14
Lj2g3v1267140.1
– PREDICTED: SKP1-like protein 1B isoform 2 [Vitis vinifera] gi|225457883|ref|XP_002270061.1|
Domains
13
Lj2g3v1670950.1
– PREDICTED: SKP1-like protein 1A-like [Glycine max] gi|356496612|ref|XP_003517160.1|
Domains
13
Lj2g3v3058520.1
– Skp1/Ask1-like protein [Zantedeschia hybrid cultivar] gi|47176688|gb|AAT12490.1|
Domains
13
Lj2g3v3084340.1
– SKP1 component-like 1 [Humulus lupulus] gi|151564277|gb|ABS17589.1|
Domains
6
Lj4g3v2366270.2
– PREDICTED: cullin-1-like isoform X1 [Cicer arietinum] gi|502151109|ref|XP_004508282.1|
Domains
16
Lj4g3v2366280.1
–
Domains
10
Lj5g3v0186680.1
– PREDICTED: SKP1-like protein 1A-like [Glycine max] gi|356496612|ref|XP_003517160.1|
Domains
13
Lj5g3v2242520.1
– PREDICTED: SKP1-like protein 1A [Vitis vinifera] gi|225428047|ref|XP_002279232.1|
Domains
13
Lj5g3v2243530.1
– PREDICTED: SKP1-like protein 1A [Vitis vinifera] gi|225428047|ref|XP_002279232.1|
Domains
13
LotjaGi1g1v0477300.1
– SKP1 family protein; TAIR: AT3G61415.1 SKP1-like 21; Swiss-Prot: sp|Q8LF97|ASK21_ARATH SKP1-like protein 21; TrEMBL-Plants: tr|I1L6J4|I1L6J4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0477300
Domains
14
LotjaGi2g1v0297400.1
– SKP1-like protein; TAIR: AT1G75950.1 S phase kinase-associated protein 1; Swiss-Prot: sp|Q39255|SKP1A_ARATH SKP1-like protein 1A; TrEMBL-Plants: tr|T2DMS9|T2DMS9_PHAVU SKP1-like protein; Found in the gene: LotjaGi2g1v0297400
Domains
16
LotjaGi2g1v0379100.1
– SKP1-like protein; TAIR: AT1G75950.1 S phase kinase-associated protein 1; Swiss-Prot: sp|Q39255|SKP1A_ARATH SKP1-like protein 1A; TrEMBL-Plants: tr|I3SWX0|I3SWX0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0379100
Domains
16
LotjaGi2g1v0379100.2
– SKP1-like protein; TAIR: AT4G35920.1 PLAC8 family protein; Swiss-Prot: sp|B6SJQ0|CNR13_MAIZE Cell number regulator 13; TrEMBL-Plants: tr|I1J8I6|I1J8I6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0379100
Domains
21
LotjaGi3g1v0344100.1
– SKP1; TAIR: AT1G20140.1 SKP1-like 4; Swiss-Prot: sp|Q9LNT9|ASK4_ARATH SKP1-like protein 4; TrEMBL-Plants: tr|A0A1J7H518|A0A1J7H518_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0344100
Domains
16
LotjaGi3g1v0384100.1
– SKP1 family protein; TAIR: AT3G61415.1 SKP1-like 21; Swiss-Prot: sp|Q8LF97|ASK21_ARATH SKP1-like protein 21; TrEMBL-Plants: tr|A0A0S3SZ27|A0A0S3SZ27_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0384100
Domains
16
LotjaGi3g1v0384100.2
– SKP1 family protein; TAIR: AT3G61415.1 SKP1-like 21; Swiss-Prot: sp|Q8LF97|ASK21_ARATH SKP1-like protein 21; TrEMBL-Plants: tr|I1KI94|I1KI94_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0384100
Domains
14
LotjaGi3g1v0384100.3
– SKP1 family protein; TAIR: AT3G61415.1 SKP1-like 21; Swiss-Prot: sp|Q8LF97|ASK21_ARATH SKP1-like protein 21; TrEMBL-Plants: tr|I1KI94|I1KI94_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0384100
Domains
14
LotjaGi3g1v0384100.4
– SKP1 family protein; TAIR: AT3G61415.1 SKP1-like 21; Swiss-Prot: sp|Q8LF97|ASK21_ARATH SKP1-like protein 21; TrEMBL-Plants: tr|K7KC10|K7KC10_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0384100
Domains
16
LotjaGi3g1v0384100.5
– SKP1 family protein; TAIR: AT2G45950.1 SKP1-like 20; Swiss-Prot: sp|Q8LF97|ASK21_ARATH SKP1-like protein 21; TrEMBL-Plants: tr|I1KI94|I1KI94_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0384100
Domains
14
LotjaGi3g1v0384100.6
– SKP1 family protein; TAIR: AT3G61415.2 SKP1-like 21; Swiss-Prot: sp|Q8LF97|ASK21_ARATH SKP1-like protein 21; TrEMBL-Plants: tr|I1KI94|I1KI94_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0384100
Domains
14
LotjaGi4g1v0131700.1
– SKP1-like protein; TAIR: AT1G75950.1 S phase kinase-associated protein 1; Swiss-Prot: sp|Q39255|SKP1A_ARATH SKP1-like protein 1A; TrEMBL-Plants: tr|A0A1J7G3F5|A0A1J7G3F5_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0131700
Domains
16
LotjaGi4g1v0232700_LC.1
– SKP1-like protein; TAIR: AT1G75950.1 S phase kinase-associated protein 1; Swiss-Prot: sp|Q39255|SKP1A_ARATH SKP1-like protein 1A; TrEMBL-Plants: tr|F6GZT1|F6GZT1_VITVI Putative uncharacterized protein; Found in the gene: LotjaGi4g1v0232700_LC
Domains
22
LotjaGi4g1v0343500.1
– Cullin 1, putative; TAIR: AT4G02570.1 cullin 1; Swiss-Prot: sp|Q94AH6|CUL1_ARATH Cullin-1; TrEMBL-Plants: tr|I3SL73|I3SL73_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0343500
Domains
27
LotjaGi4g1v0343500.2
– Cullin 1, putative; TAIR: AT4G02570.1 cullin 1; Swiss-Prot: sp|Q94AH6|CUL1_ARATH Cullin-1; TrEMBL-Plants: tr|I3SL73|I3SL73_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0343500
Domains
19
LotjaGi4g1v0344200.1
– Cullin 1, putative; TAIR: AT4G02570.1 cullin 1; Swiss-Prot: sp|Q94AH6|CUL1_ARATH Cullin-1; TrEMBL-Plants: tr|I3SKE1|I3SKE1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0344200
Domains
19
LotjaGi4g1v0344200.2
– Cullin 1, putative; TAIR: AT4G02570.1 cullin 1; Swiss-Prot: sp|Q94AH6|CUL1_ARATH Cullin-1; TrEMBL-Plants: tr|I3SKE1|I3SKE1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0344200
Domains
19
LotjaGi4g1v0344200.3
– Cullin 1, putative; TAIR: AT4G02570.1 cullin 1; Swiss-Prot: sp|Q94AH6|CUL1_ARATH Cullin-1; TrEMBL-Plants: tr|I3SKE1|I3SKE1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0344200
Domains
19
LotjaGi5g1v0006400.1
– SKP1-like protein; TAIR: AT1G75950.1 S phase kinase-associated protein 1; Swiss-Prot: sp|Q39255|SKP1A_ARATH SKP1-like protein 1A; TrEMBL-Plants: tr|I3SES0|I3SES0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0006400
Domains
16
LotjaGi5g1v0348400.1
– SKP1-like protein; TAIR: AT2G25700.1 SKP1-like 3; Swiss-Prot: sp|Q9SL93|ASK3_ARATH SKP1-like protein 3; TrEMBL-Plants: tr|A0A076JVB0|A0A076JVB0_9ROSA S-phase kinase-associated protein 1-like protein 3; Found in the gene: LotjaGi5g1v0348400
Domains
16
LotjaGi5g1v0348500.1
– SKP1-like protein; TAIR: AT2G25700.1 SKP1-like 3; Swiss-Prot: sp|Q9SL93|ASK3_ARATH SKP1-like protein 3; TrEMBL-Plants: tr|A0A076JVB0|A0A076JVB0_9ROSA S-phase kinase-associated protein 1-like protein 3; Found in the gene: LotjaGi5g1v0348500
Domains
16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd18322 CDD 1 2.56