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IPR036063 is a Smr domain superfamily.
<p>This entry represents the Smr domain superfamily.</p> <p>The structure of the Smr domain has a β-α-β-α-β(2) fold. It is divided into two layers and the strand 4 is antiparallel to the rest.</p> <p>The Smr domain is an around 90-residue domain found in:</p> <ul><li>The C-terminal region of the MutS2 proteins from bacteria and plants, such as Endonuclease MutS2 from Bacillus thuringiensis.</li> <li>The small MutS related (Smr) proteins from bacteria and eukaryotes, including Ribosome rescue factor SmrB from Escherichia coli.</li> <li>Other Smr domain-containing animal and fungal proteins, including human NEDD4-binding protein 2, which has 5'-polynucleotide kinase and nicking endonuclease activity [[cite:PUB00060369]].</li></ul> <p>These proteins could be involved in mismatch repair (MMR) or/and chromosome crossing-over and segregation. It has been proposed that the Smr domain acts as a nicking endonuclease [[cite:PUB00005494], [cite:PUB00018300]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Pentatricopeptide repeat-containing protein family; TAIR: AT1G18900.1 Pentatricopeptide repeat (PPR) superfamily protein; Swiss-Prot: sp|Q8GYP6|PPR49_ARATH Pentatricopeptide repeat-containing protein At1g18900; TrEMBL-Plants: tr|A0A151S797|A0A151S797_CAJCA Pentatricopeptide repeat-containing protein family; Found in the gene: LotjaGi1g1v0188000 | 22 | ||
| – | Smr domain-containing protein; TAIR: AT2G26280.1 CTC-interacting domain 7; Swiss-Prot: sp|O64843|CID7_ARATH Polyadenylate-binding protein-interacting protein 7; TrEMBL-Plants: tr|A0A0L9UH72|A0A0L9UH72_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0372100 | 12 | ||
| – | Smr (Small MutS-related) domain protein; TAIR: AT5G23520.1 smr (Small MutS Related) domain-containing protein; Swiss-Prot: sp|Q86UW6|N4BP2_HUMAN NEDD4-binding protein 2; TrEMBL-Plants: tr|K7LFV6|K7LFV6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0492900 | 12 | ||
| – | Pentatricopeptide repeat-containing protein, putative; TAIR: AT2G31400.1 s uncoupled 1; Swiss-Prot: sp|Q9SIC9|PP178_ARATH Pentatricopeptide repeat-containing protein At2g31400, chloroplastic; TrEMBL-Plants: tr|G7KS10|G7KS10_MEDTR PPR containing plant protein; Found in the gene: LotjaGi1g1v0521700 | 16 | ||
| – | DNA mismatch repair protein MutS2; TAIR: AT1G65070.2 DNA mismatch repair protein MutS, type 2; Swiss-Prot: sp|P73625|MUTS2_SYNY3 Endonuclease MutS2; TrEMBL-Plants: tr|I1KLI9|I1KLI9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0055400 | 24 | ||
| – | Smr domain-containing protein; TAIR: AT2G26280.1 CTC-interacting domain 7; Swiss-Prot: sp|O64843|CID7_ARATH Polyadenylate-binding protein-interacting protein 7; TrEMBL-Plants: tr|A0A072VDP3|A0A072VDP3_MEDTR Smr (Small MutS-related) domain protein; Found in the gene: LotjaGi5g1v0048800 | 16 | ||
| – | Pentatricopeptide repeat-containing protein; TAIR: AT2G17033.1 pentatricopeptide (PPR) repeat-containing protein; Swiss-Prot: sp|Q8GWA9|PP157_ARATH Pentatricopeptide repeat-containing protein At2g17033; TrEMBL-Plants: tr|A0A1J7HIQ9|A0A1J7HIQ9_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0351300 | 13 | ||
| – | Smr domain-containing protein, putative; TAIR: AT5G58720.1 smr (Small MutS Related) domain-containing protein; Swiss-Prot: sp|O65573|Y5872_ARATH SMR domain-containing protein At5g58720; TrEMBL-Plants: tr|A0A1J7H576|A0A1J7H576_LUPAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0113600 | 12 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 12.50 |