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IPR002194

Source: InterPro

Description

IPR002194 is a Chaperonin TCP-1, conserved site.

<p>The TCP-1 protein [[cite:PUB00004127], [cite:PUB00001019]] (Tailless Complex Polypeptide 1) was first identified in mice where it is especially abundant in testis but present in all cell types. It has since been found and characterised in many other animal species, as well as in yeast, plants and protists. TCP-1 is a highly conserved protein of about 60kDa (556 to 560 residues) which participates in a hetero-oligomeric 900kDa double-torus shaped particle [[cite:PUB00004129]] with 6 to 8 other different subunits. These subunits, the chaperonin containing TCP-1 (CCT) subunit beta, gamma, delta, epsilon, zeta and eta are evolutionary related to TCP-1 itself [[cite:PUB00001034], [cite:PUB00005432]]. The CCT is known to act as a molecular chaperone for tubulin, actin and probably some other proteins.</p> <p>The CCT subunits are highly related to archaebacterial counterparts:</p> <ul><li>TF55 and TF56 [[cite:PUB00004112]], a molecular chaperone from Sulfolobus shibatae. TF55 has ATPase activity, is known to bind unfolded polypeptides and forms a oligomeric complex of two stacked nine-membered rings.</li> <li>Thermosome [[cite:PUB00000756]], from Thermoplasma acidophilum. The thermosome is composed of two subunits (alpha and beta) and also seems to be a chaperone with ATPase activity. It forms an oligomeric complex of eight-membered rings.</li></ul> <p>The TCP-1 family of proteins are weakly, but significantly [[cite:PUB00004124]], related to the cpn60/groEL chaperonin family (see [interpro:IPR001844]).</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005524
Molecular function ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
Subterm of
GO:0006457
Biological process Protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
Subterm of
GO:0051082
Molecular function Unfolded protein binding Interacting selectively and non-covalently with an unfolded protein.
Subterm of

Associated Lotus transcripts 38

Transcript Name Description Predicted domains Domain count
Lj0g3v0243669.1
– Cytosolic chaperonin, delta subunit [Glycine max] gi|255957392|emb|CBA13550.1|
Domains
20
Lj0g3v0306429.1
– PREDICTED: T-complex protein 1 subunit epsilon-like [Glycine max] gi|356567490|ref|XP_003551952.1|
Domains
20
Lj1g3v0488910.1
– PREDICTED: T-complex protein 1 subunit theta-like [Cicer arietinum] gi|502123956|ref|XP_004498325.1|
Domains
20
Lj1g3v3328880.1
– PREDICTED: T-complex protein 1 subunit zeta-like [Glycine max] gi|356569084|ref|XP_003552736.1|
Domains
20
Lj2g3v0546890.1
– PREDICTED: T-complex protein 1 subunit gamma-like [Cicer arietinum] gi|502162879|ref|XP_004512647.1|
Domains
24
Lj4g3v2644180.1
– PREDICTED: T-complex protein 1 subunit alpha-like [Cicer arietinum] gi|502140465|ref|XP_004504226.1|
Domains
22
Lj4g3v3114050.1
– Cytosolic chaperonin, delta subunit [Glycine max] gi|255957392|emb|CBA13550.1|
Domains
20
Lj6g3v0776070.1
– PREDICTED: T-complex protein 1 subunit beta-like isoform X2 [Cicer arietinum] gi|502104047|ref|XP_004492422.1|
Domains
22
LotjaGi1g1v0058100.1
– T-complex protein 1 subunit eta; TAIR: AT3G11830.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q9SF16|TCPH_ARATH T-complex protein 1 subunit eta; TrEMBL-Plants: tr|G7K2W1|G7K2W1_MEDTR TCP-1/cpn60 chaperonin family protein; Found in the gene: LotjaGi1g1v0058100
Domains
23
LotjaGi1g1v0058100.2
– T-complex protein 1 subunit eta; TAIR: AT3G11830.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q9SF16|TCPH_ARATH T-complex protein 1 subunit eta; TrEMBL-Plants: tr|A0A0L9UVX2|A0A0L9UVX2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0058100
Domains
22
LotjaGi1g1v0058100.3
– T-complex protein 1 subunit eta; TAIR: AT3G11830.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q9SF16|TCPH_ARATH T-complex protein 1 subunit eta; TrEMBL-Plants: tr|G7K2W1|G7K2W1_MEDTR TCP-1/cpn60 chaperonin family protein; Found in the gene: LotjaGi1g1v0058100
Domains
23
LotjaGi1g1v0058100.4
– T-complex protein 1 subunit eta; TAIR: AT3G11830.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q9SF16|TCPH_ARATH T-complex protein 1 subunit eta; TrEMBL-Plants: tr|A0A0L9UVX2|A0A0L9UVX2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0058100
Domains
22
LotjaGi1g1v0058100.5
– T-complex protein 1 subunit eta; TAIR: AT3G11830.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q9SF16|TCPH_ARATH T-complex protein 1 subunit eta; TrEMBL-Plants: tr|A0A0L9UVX2|A0A0L9UVX2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0058100
Domains
21
LotjaGi1g1v0219200.1
– T-complex protein 1 subunit theta; TAIR: AT3G03960.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q94K05|TCPQ_ARATH T-complex protein 1 subunit theta; TrEMBL-Plants: tr|V7C3G7|V7C3G7_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0219200
Domains
22
LotjaGi1g1v0438900.1
– T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|A0A1J7HDU4|A0A1J7HDU4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0438900
Domains
22
LotjaGi1g1v0438900.2
– T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|A0A1J7HDU4|A0A1J7HDU4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0438900
Domains
22
LotjaGi1g1v0438900.3
– T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|I1LRE4|I1LRE4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0438900
Domains
22
LotjaGi1g1v0438900.4
– T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|I1LRE4|I1LRE4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0438900
Domains
22
LotjaGi1g1v0438900.5
– T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|A0A1J7HDU4|A0A1J7HDU4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0438900
Domains
22
LotjaGi1g1v0551600.1
– T-complex protein 1 subunit zeta; TAIR: AT3G02530.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q9M888|TCPZA_ARATH T-complex protein 1 subunit zeta 1; TrEMBL-Plants: tr|A0A151TDH0|A0A151TDH0_CAJCA T-complex protein 1 subunit zeta; Found in the gene: LotjaGi1g1v0551600
Domains
20
LotjaGi1g1v0551600.2
– T-complex protein 1 subunit zeta; TAIR: AT3G02530.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q9M888|TCPZA_ARATH T-complex protein 1 subunit zeta 1; TrEMBL-Plants: tr|A0A072TVM3|A0A072TVM3_MEDTR TCP-1/cpn60 chaperonin family protein; Found in the gene: LotjaGi1g1v0551600
Domains
20
LotjaGi1g1v0551600.3
– T-complex protein 1 subunit zeta; TAIR: AT3G02530.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q9M888|TCPZA_ARATH T-complex protein 1 subunit zeta 1; TrEMBL-Plants: tr|A0A072TVM3|A0A072TVM3_MEDTR TCP-1/cpn60 chaperonin family protein; Found in the gene: LotjaGi1g1v0551600
Domains
20
LotjaGi2g1v0168600.1
– T-complex protein 1 subunit gamma; TAIR: AT5G26360.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q84WV1|TCPG_ARATH T-complex protein 1 subunit gamma; TrEMBL-Plants: tr|A0A1J7HGR3|A0A1J7HGR3_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0168600
Domains
24
LotjaGi2g1v0168600.2
– T-complex protein 1 subunit gamma; TAIR: AT5G26360.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q84WV1|TCPG_ARATH T-complex protein 1 subunit gamma; TrEMBL-Plants: tr|G7IPS8|G7IPS8_MEDTR T-complex protein 1 subunit gamma; Found in the gene: LotjaGi2g1v0168600
Domains
24
LotjaGi2g1v0168600.3
– T-complex protein 1 subunit gamma; TAIR: AT5G26360.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q84WV1|TCPG_ARATH T-complex protein 1 subunit gamma; TrEMBL-Plants: tr|G7IPS8|G7IPS8_MEDTR T-complex protein 1 subunit gamma; Found in the gene: LotjaGi2g1v0168600
Domains
23
LotjaGi4g1v0068500.1
– T-complex protein 1 subunit delta; TAIR: AT3G18190.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q9LV21|TCPD_ARATH T-complex protein 1 subunit delta; TrEMBL-Plants: tr|C7C6E1|C7C6E1_SOYBN T-complex protein 1 subunit delta; Found in the gene: LotjaGi4g1v0068500
Domains
20
LotjaGi4g1v0068500.2
– T-complex protein 1 subunit delta; TAIR: AT3G18190.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q9LV21|TCPD_ARATH T-complex protein 1 subunit delta; TrEMBL-Plants: tr|A0A072V1S9|A0A072V1S9_MEDTR T-complex protein 1 subunit delta; Found in the gene: LotjaGi4g1v0068500
Domains
17
LotjaGi4g1v0068500.3
– T-complex protein 1 subunit delta; TAIR: AT3G18190.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q9LV21|TCPD_ARATH T-complex protein 1 subunit delta; TrEMBL-Plants: tr|C7C6E1|C7C6E1_SOYBN T-complex protein 1 subunit delta; Found in the gene: LotjaGi4g1v0068500
Domains
20
LotjaGi4g1v0384900.1
– T-complex protein 1 subunit alpha; TAIR: AT3G20050.1 T-complex protein 1 alpha subunit; Swiss-Prot: sp|P28769|TCPA_ARATH T-complex protein 1 subunit alpha; TrEMBL-Plants: tr|A0A0L9TJL4|A0A0L9TJL4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0384900
Domains
22
LotjaGi4g1v0384900.2
– T-complex protein 1 subunit alpha; TAIR: AT3G20050.1 T-complex protein 1 alpha subunit; Swiss-Prot: sp|P28769|TCPA_ARATH T-complex protein 1 subunit alpha; TrEMBL-Plants: tr|A0A0L9TJL4|A0A0L9TJL4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0384900
Domains
21
LotjaGi4g1v0461000.1
– T-complex protein 1 subunit delta; TAIR: AT3G18190.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q9LV21|TCPD_ARATH T-complex protein 1 subunit delta; TrEMBL-Plants: tr|C7C6E1|C7C6E1_SOYBN T-complex protein 1 subunit delta; Found in the gene: LotjaGi4g1v0461000
Domains
20
LotjaGi4g1v0461000.2
– T-complex protein 1 subunit delta; TAIR: AT3G18190.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q9LV21|TCPD_ARATH T-complex protein 1 subunit delta; TrEMBL-Plants: tr|C7C6E1|C7C6E1_SOYBN T-complex protein 1 subunit delta; Found in the gene: LotjaGi4g1v0461000
Domains
20
LotjaGi4g1v0461000.3
– T-complex protein 1 subunit delta; TAIR: AT3G18190.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q9LV21|TCPD_ARATH T-complex protein 1 subunit delta; TrEMBL-Plants: tr|A0A072V1S9|A0A072V1S9_MEDTR T-complex protein 1 subunit delta; Found in the gene: LotjaGi4g1v0461000
Domains
17
LotjaGi6g1v0096800.1
– T-complex protein 1; TAIR: AT1G24510.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|O04450|TCPE_ARATH T-complex protein 1 subunit epsilon; TrEMBL-Plants: tr|A0A0L9UAZ1|A0A0L9UAZ1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0096800
Domains
21
LotjaGi6g1v0096800.2
– T-complex protein 1; TAIR: AT1G24510.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|O04450|TCPE_ARATH T-complex protein 1 subunit epsilon; TrEMBL-Plants: tr|I1MYL7|I1MYL7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0096800
Domains
19
LotjaGi6g1v0145000.1
– T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|A0A151TNM7|A0A151TNM7_CAJCA T-complex protein 1 subunit beta; Found in the gene: LotjaGi6g1v0145000
Domains
22
LotjaGi6g1v0145000.2
– T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|A0A151TNM7|A0A151TNM7_CAJCA T-complex protein 1 subunit beta; Found in the gene: LotjaGi6g1v0145000
Domains
22
LotjaGi6g1v0145000.3
– T-complex protein 1 subunit beta; TAIR: AT5G20890.1 TCP-1/cpn60 chaperonin family protein; Swiss-Prot: sp|Q940P8|TCPB_ARATH T-complex protein 1 subunit beta; TrEMBL-Plants: tr|A0A151TNM7|A0A151TNM7_CAJCA T-complex protein 1 subunit beta; Found in the gene: LotjaGi6g1v0145000
Domains
22

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd03336 CDD 1 2.63