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IPR004095 is a TGS.
<p>The TGS domain (named for its presence ThrRS, GTPase, and SpoT) is present in a number of enzymes, for example, in threonyl-tRNA synthetase (ThrRS), a distinct family of GTPases (the OBG family), and guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (SpoT) [[cite:PUB00007363], [cite:PUB00094831]] and synthetase (RelA) which are involved in stringent response in bacteria. The TGS domain is also present at the N-terminal of the uridine kinase from the spirochaete Treponema pallidum [[cite:PUB00094832]] (but not any other organism, including the related spirochaete Borrelia burgdorferi).</p> <p>TGS is a small domain that consists of ~50 amino acid residues and has nucleic acid binding affinity. It is arranged in a six-stranded half-barrel that curves around an α-helix and belongs to the β-grasp fold superfamily [[cite:PUB00016351], [cite:PUB00036769], [cite:PUB00034476]]. The function of the TGS domain of SpoT is in transcription of survival and virulence genes in response to environmental stress [[cite:PUB00095793]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: developmentally-regulated GTP-binding protein 1-like [Glycine max] gi|356516297|ref|XP_003526832.1| | 25 | ||
| – | GTP pyrophosphokinase [Medicago truncatula] gi|357481159|ref|XP_003610865.1| | 8 | ||
| – | PREDICTED: GTP pyrophosphokinase-like isoform X1 [Cicer arietinum] gi|502112635|ref|XP_004494394.1| | 25 | ||
| – | PREDICTED: threonyl-tRNA synthetase, mitochondrial-like [Glycine max] gi|356497888|ref|XP_003517788.1| | 25 | ||
| – | PREDICTED: guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase-like isoform X1 [Cicer arietinum] gi|502159240|ref|XP_004511439.1| | 17 | ||
| – | Developmentally regulated G-protein 1 isoform 1 [Theobroma cacao] gi|508779961|gb|EOY27217.1| | 23 | ||
| – | GTPase obg; TAIR: AT4G39520.1 GTP-binding protein-like protein; Swiss-Prot: sp|Q9SVA6|DRG3_ARATH Developmentally-regulated G-protein 3; TrEMBL-Plants: tr|A0A1J7H966|A0A1J7H966_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0312100 | 25 | ||
| – | GTP pyrophosphokinase; TAIR: AT4G02260.2 RELA/SPOT homolog 1; Swiss-Prot: sp|P0DKG8|RSH1L_ARATH Putative GTP diphosphokinase RSH1, chloroplastic; TrEMBL-Plants: tr|A0A0B2QGP0|A0A0B2QGP0_GLYSO GTP pyrophosphokinase; Found in the gene: LotjaGi1g1v0763000 | 31 | ||
| – | GTP pyrophosphokinase; TAIR: AT4G02260.2 RELA/SPOT homolog 1; Swiss-Prot: sp|P0DKG8|RSH1L_ARATH Putative GTP diphosphokinase RSH1, chloroplastic; TrEMBL-Plants: tr|A0A0B2QGP0|A0A0B2QGP0_GLYSO GTP pyrophosphokinase; Found in the gene: LotjaGi1g1v0763000 | 32 | ||
| – | GTP pyrophosphokinase; TAIR: AT4G02260.2 RELA/SPOT homolog 1; Swiss-Prot: sp|P0DKG8|RSH1L_ARATH Putative GTP diphosphokinase RSH1, chloroplastic; TrEMBL-Plants: tr|A0A0B2QGP0|A0A0B2QGP0_GLYSO GTP pyrophosphokinase; Found in the gene: LotjaGi1g1v0763000 | 32 | ||
| – | GTP pyrophosphokinase; TAIR: AT4G02260.2 RELA/SPOT homolog 1; Swiss-Prot: sp|P0DKG8|RSH1L_ARATH Putative GTP diphosphokinase RSH1, chloroplastic; TrEMBL-Plants: tr|A0A0B2QGP0|A0A0B2QGP0_GLYSO GTP pyrophosphokinase; Found in the gene: LotjaGi1g1v0763000 | 31 | ||
| – | Threonine--tRNA ligase; TAIR: AT5G26830.1 Threonyl-tRNA synthetase; Swiss-Prot: sp|O04630|SYTM1_ARATH Threonine--tRNA ligase, mitochondrial 1; TrEMBL-Plants: tr|A0A0S3T3W6|A0A0S3T3W6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0318100 | 35 | ||
| – | Threonine--tRNA ligase; TAIR: AT5G26830.1 Threonyl-tRNA synthetase; Swiss-Prot: sp|O04630|SYTM1_ARATH Threonine--tRNA ligase, mitochondrial 1; TrEMBL-Plants: tr|A0A0S3T3W6|A0A0S3T3W6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0318100 | 35 | ||
| – | Threonine--tRNA ligase; TAIR: AT5G26830.1 Threonyl-tRNA synthetase; Swiss-Prot: sp|O04630|SYTM1_ARATH Threonine--tRNA ligase, mitochondrial 1; TrEMBL-Plants: tr|A0A0S3T3W6|A0A0S3T3W6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0318100 | 35 | ||
| – | Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase; TAIR: AT1G54130.1 RELA/SPOT homolog 3; Swiss-Prot: sp|Q9SYH1|RSH3C_ARATH Probable GTP diphosphokinase RSH3, chloroplastic; TrEMBL-Plants: tr|A0A0B2R105|A0A0B2R105_GLYSO Putative GTP pyrophosphokinase; Found in the gene: LotjaGi2g1v0448600 | 22 | ||
| – | Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase; TAIR: AT1G54130.1 RELA/SPOT homolog 3; Swiss-Prot: sp|Q9SYH1|RSH3C_ARATH Probable GTP diphosphokinase RSH3, chloroplastic; TrEMBL-Plants: tr|A0A0B2R105|A0A0B2R105_GLYSO Putative GTP pyrophosphokinase; Found in the gene: LotjaGi2g1v0448600 | 22 | ||
| – | Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase, putative; TAIR: AT1G54130.1 RELA/SPOT homolog 3; Swiss-Prot: sp|Q9SYH1|RSH3C_ARATH Probable GTP diphosphokinase RSH3, chloroplastic; TrEMBL-Plants: tr|A0A0R0HH22|A0A0R0HH22_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0448600 | 22 | ||
| – | Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase; TAIR: AT1G54130.1 RELA/SPOT homolog 3; Swiss-Prot: sp|Q9SYH1|RSH3C_ARATH Probable GTP diphosphokinase RSH3, chloroplastic; TrEMBL-Plants: tr|A0A0R0LJ13|A0A0R0LJ13_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0448600 | 22 | ||
| – | Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase; TAIR: AT1G54130.1 RELA/SPOT homolog 3; Swiss-Prot: sp|Q9SYH1|RSH3C_ARATH Probable GTP diphosphokinase RSH3, chloroplastic; TrEMBL-Plants: tr|A0A0R0LJ13|A0A0R0LJ13_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0448600 | 22 | ||
| – | Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase; TAIR: AT1G54130.1 RELA/SPOT homolog 3; Swiss-Prot: sp|Q9SYH1|RSH3C_ARATH Probable GTP diphosphokinase RSH3, chloroplastic; TrEMBL-Plants: tr|A0A0B2R105|A0A0B2R105_GLYSO Putative GTP pyrophosphokinase; Found in the gene: LotjaGi2g1v0448600 | 22 | ||
| – | GTPase Obg; TAIR: AT1G72660.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q9CAI1|DRG2_ARATH Developmentally-regulated G-protein 2; TrEMBL-Plants: tr|I1KHA2|I1KHA2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0416000 | 26 | ||
| – | Developmentally regulated GTP binding protein; TAIR: AT1G17470.1 developmentally regulated G-protein 1; Swiss-Prot: sp|Q9LQK0|DRG1_ARATH Developmentally-regulated G-protein 1; TrEMBL-Plants: tr|I1KHA2|I1KHA2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0416000 | 16 | ||
| – | GTPase Obg; TAIR: AT1G72660.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q9CAI1|DRG2_ARATH Developmentally-regulated G-protein 2; TrEMBL-Plants: tr|I1KHA2|I1KHA2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0416000 | 24 | ||
| – | GTPase Obg; TAIR: AT1G72660.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q9CAI1|DRG2_ARATH Developmentally-regulated G-protein 2; TrEMBL-Plants: tr|I1KHA2|I1KHA2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0416000 | 26 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 4.17 |