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IPR004182 is a GRAM domain.
<p>The GRAM domain is found in glucosyltransferases, myotubularins and other putative membrane-associated proteins. It is normally about 70 amino acids in length. It is thought to be an intracellular protein-binding or lipid-binding signalling domain, which has an important function in membrane-associated processes. The structure of the GRAM domain is similar to that found in PH domains [[cite:PUB00019649]]. Mutations in the GRAM domain of myotubularins cause a muscle disease, which suggests that the domain is essential for the full function of the enzyme [[cite:PUB00019649]]. Myotubularin-related proteins are a large subfamily of protein tyrosine phosphatases (PTPs) that dephosphorylate D3-phosphorylated inositol lipids [[cite:PUB00022130]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | GLABRA2 expression modulator [Medicago truncatula] gi|357465343|ref|XP_003602953.1| | 7 | ||
| – | 5 | |||
| – | PREDICTED: GLABRA2 expression modulator-like [Glycine max] gi|356566022|ref|XP_003551234.1| | 6 | ||
| – | GEM-like protein [Medicago truncatula] gi|357499751|ref|XP_003620164.1| | 5 | ||
| – | GEM-like protein [Medicago truncatula] gi|357508343|ref|XP_003624460.1| | 7 | ||
| – | PREDICTED: C2 and GRAM domain-containing protein At1g03370-like [Cicer arietinum] gi|502142930|ref|XP_004505156.1| | 18 | ||
| – | GEM-like protein [Medicago truncatula] gi|357508343|ref|XP_003624460.1| | 7 | ||
| – | PREDICTED: GEM-like protein 4-like [Cicer arietinum] gi|502171563|ref|XP_004515060.1| | 6 | ||
| – | PREDICTED: myotubularin-related protein 2-like [Cicer arietinum] gi|502118244|ref|XP_004496171.1| | 9 | ||
| – | PREDICTED: GEM-like protein 4-like [Cicer arietinum] gi|502121267|ref|XP_004497247.1| | 7 | ||
| – | PREDICTED: GEM-like protein 4-like [Cicer arietinum] gi|502121267|ref|XP_004497247.1| | 7 | ||
| – | PREDICTED: GEM-like protein 4-like [Cicer arietinum] gi|502121267|ref|XP_004497247.1| | 5 | ||
| – | PREDICTED: GEM-like protein 4-like [Glycine max] gi|356536453|ref|XP_003536752.1| | 5 | ||
| – | PREDICTED: C2 and GRAM domain-containing protein At1g03370-like [Glycine max] gi|356532855|ref|XP_003534985.1| | 19 | ||
| – | C2 and GRAM domain-containing protein; TAIR: AT5G50170.1 C2 calcium/lipid-binding and GRAM domain containing protein; Swiss-Prot: sp|Q9FGS8|C2GR2_ARATH C2 and GRAM domain-containing protein At5g50170; TrEMBL-Plants: tr|A0A0R0K9Z2|A0A0R0K9Z2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0196800 | 21 | ||
| – | C2 and GRAM domain-containing protein; TAIR: AT5G50170.1 C2 calcium/lipid-binding and GRAM domain containing protein; Swiss-Prot: sp|Q9FGS8|C2GR2_ARATH C2 and GRAM domain-containing protein At5g50170; TrEMBL-Plants: tr|A0A0R0K9Z2|A0A0R0K9Z2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0196800 | 21 | ||
| – | GEM-like protein 1; TAIR: AT1G28200.1 FH interacting protein 1; Swiss-Prot: sp|Q9SE96|GEML1_ARATH GEM-like protein 1; TrEMBL-Plants: tr|A0A0L9UGE2|A0A0L9UGE2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0349700 | 10 | ||
| – | GRAM domain protein/ABA-responsive-like protein; TAIR: AT5G13200.1 GRAM domain family protein; Swiss-Prot: sp|Q9LYV6|GEML5_ARATH GEM-like protein 5; TrEMBL-Plants: tr|I3TA12|I3TA12_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0631000 | 10 | ||
| – | Myotubularin; TAIR: AT3G10550.1 Myotubularin-like phosphatases II superfamily; Swiss-Prot: sp|F4J3T8|MYTM1_ARATH Phosphatidylinositol-3-phosphatase myotubularin-1; TrEMBL-Plants: tr|V7BH90|V7BH90_PHAVU Uncharacterized protein; Found in the gene: LotjaGi2g1v0157200 | 18 | ||
| – | GRAM domain protein/ABA-responsive-like protein; TAIR: AT5G23370.1 GRAM domain-containing protein / ABA-responsive protein-like protein; Swiss-Prot: sp|Q9FMW4|GEML8_ARATH Putative GEM-like protein 8; TrEMBL-Plants: tr|G7KKC8|G7KKC8_MEDTR GRAM domain protein/ABA-responsive-like protein; Found in the gene: LotjaGi2g1v0178700 | 9 | ||
| – | GRAM domain family protein; TAIR: AT1G02120.1 GRAM domain family protein; Swiss-Prot: sp|F4HVW5|VAD1_ARATH Protein VASCULAR ASSOCIATED DEATH 1, chloroplastic; TrEMBL-Plants: tr|A0A072TWG7|A0A072TWG7_MEDTR PH-GRAM1-TCB1D9-TCB1D9B domain protein; Found in the gene: LotjaGi3g1v0067300 | 16 | ||
| – | GRAM domain family protein; TAIR: AT1G02120.1 GRAM domain family protein; Swiss-Prot: sp|F4HVW5|VAD1_ARATH Protein VASCULAR ASSOCIATED DEATH 1, chloroplastic; TrEMBL-Plants: tr|A0A072TJX9|A0A072TJX9_MEDTR PH-GRAM1-TCB1D9-TCB1D9B domain protein; Found in the gene: LotjaGi3g1v0067300 | 16 | ||
| – | GRAM domain family protein; TAIR: AT1G02120.1 GRAM domain family protein; Swiss-Prot: sp|F4HVW5|VAD1_ARATH Protein VASCULAR ASSOCIATED DEATH 1, chloroplastic; TrEMBL-Plants: tr|A0A072TJX9|A0A072TJX9_MEDTR PH-GRAM1-TCB1D9-TCB1D9B domain protein; Found in the gene: LotjaGi3g1v0067300 | 16 | ||
| – | GRAM domain family protein; TAIR: AT1G02120.1 GRAM domain family protein; Swiss-Prot: sp|F4HVW5|VAD1_ARATH Protein VASCULAR ASSOCIATED DEATH 1, chloroplastic; TrEMBL-Plants: tr|A0A072TWG7|A0A072TWG7_MEDTR PH-GRAM1-TCB1D9-TCB1D9B domain protein; Found in the gene: LotjaGi3g1v0067300 | 16 | ||
| – | C2 and GRAM domain-containing protein; TAIR: AT1G03370.1 C2 calcium/lipid-binding and GRAM domain containing protein; Swiss-Prot: sp|Q9ZVT9|C2GR1_ARATH C2 and GRAM domain-containing protein At1g03370; TrEMBL-Plants: tr|I1KNM4|I1KNM4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0005000 | 24 | ||
| – | C2 and GRAM domain-containing protein; TAIR: AT1G03370.1 C2 calcium/lipid-binding and GRAM domain containing protein; Swiss-Prot: sp|Q9ZVT9|C2GR1_ARATH C2 and GRAM domain-containing protein At1g03370; TrEMBL-Plants: tr|I1KNM4|I1KNM4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0005000 | 24 | ||
| – | C2 domain-containing protein / GRAM domain-containing protein; TAIR: AT3G59660.1 C2 domain-containing protein / GRAM domain-containing protein; Swiss-Prot: sp|Q8W4D4|BAGP1_ARATH BAG-associated GRAM protein 1; TrEMBL-Plants: tr|K7K882|K7K882_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0068800 | 28 | ||
| – | C2 domain-containing protein / GRAM domain-containing protein; TAIR: AT3G59660.1 C2 domain-containing protein / GRAM domain-containing protein; Swiss-Prot: sp|Q8W4D4|BAGP1_ARATH BAG-associated GRAM protein 1; TrEMBL-Plants: tr|K7K881|K7K881_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0068800 | 20 | ||
| – | C2 domain-containing protein / GRAM domain-containing protein; TAIR: AT3G59660.1 C2 domain-containing protein / GRAM domain-containing protein; Swiss-Prot: sp|Q8W4D4|BAGP1_ARATH BAG-associated GRAM protein 1; TrEMBL-Plants: tr|K7K882|K7K882_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0068800 | 20 | ||
| – | GRAM domain protein/ABA-responsive-like protein; TAIR: AT2G22475.1 GRAM domain family protein; Swiss-Prot: sp|Q8S8F8|GEM_ARATH GLABRA2 expression modulator; TrEMBL-Plants: tr|A0A0B2QS05|A0A0B2QS05_GLYSO GLABRA2 expression modulator; Found in the gene: LotjaGi4g1v0159300 | 10 | ||
| – | GRAM domain protein/ABA-responsive-like protein; TAIR: AT5G08350.1 GRAM domain-containing protein / ABA-responsive protein-like protein; Swiss-Prot: sp|Q9FTA0|GEML4_ARATH GEM-like protein 4; TrEMBL-Plants: tr|I3SIE9|I3SIE9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0438500 | 9 | ||
| – | GRAM domain protein/ABA-responsive-like protein; TAIR: AT5G08350.1 GRAM domain-containing protein / ABA-responsive protein-like protein; Swiss-Prot: sp|Q9FTA0|GEML4_ARATH GEM-like protein 4; TrEMBL-Plants: tr|B7FJD2|B7FJD2_MEDTR GRAM domain protein/ABA-responsive-like protein; Found in the gene: LotjaGi5g1v0353600 | 8 | ||
| – | GRAM domain protein/ABA-responsive-like protein; TAIR: AT5G08350.1 GRAM domain-containing protein / ABA-responsive protein-like protein; Swiss-Prot: sp|Q9FTA0|GEML4_ARATH GEM-like protein 4; TrEMBL-Plants: tr|B7FJD2|B7FJD2_MEDTR GRAM domain protein/ABA-responsive-like protein; Found in the gene: LotjaGi5g1v0353600 | 8 | ||
| – | GRAM domain protein/ABA-responsive-like protein; TAIR: AT5G23370.1 GRAM domain-containing protein / ABA-responsive protein-like protein; Swiss-Prot: sp|Q9FMW4|GEML8_ARATH Putative GEM-like protein 8; TrEMBL-Plants: tr|A0A072W2G8|A0A072W2G8_MEDTR GRAM domain protein/ABA-responsive-like protein; Found in the gene: LotjaGi5g1v0353700 | 8 | ||
| – | GRAM domain protein/ABA-responsive-like protein; TAIR: AT5G08350.1 GRAM domain-containing protein / ABA-responsive protein-like protein; Swiss-Prot: sp|Q9FTA0|GEML4_ARATH GEM-like protein 4; TrEMBL-Plants: tr|K7LM06|K7LM06_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0353700 | 8 | ||
| – | GRAM domain protein/ABA-responsive-like protein; TAIR: AT5G08350.1 GRAM domain-containing protein / ABA-responsive protein-like protein; Swiss-Prot: sp|Q9FTA0|GEML4_ARATH GEM-like protein 4; TrEMBL-Plants: tr|K7LM06|K7LM06_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0353700 | 8 | ||
| – | C2 and GRAM domain-containing protein; TAIR: AT1G03370.1 C2 calcium/lipid-binding and GRAM domain containing protein; Swiss-Prot: sp|Q9ZVT9|C2GR1_ARATH C2 and GRAM domain-containing protein At1g03370; TrEMBL-Plants: tr|A0A0B2S6D4|A0A0B2S6D4_GLYSO C2 and GRAM domain-containing protein; Found in the gene: LotjaGi6g1v0281500 | 24 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 2.70 |