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IPR023123 is a Tubulin, C-terminal.
<p>Microtubules are polymers of tubulin, a dimer of two 55kDa subunits, designated alpha and beta [[cite:PUB00000039], [cite:PUB00000978]]. Within the microtubule lattice, α-β heterodimers associate in a head-to-tail fashion, giving rise to microtubule polarity. Fluorescent labelling studies have suggested that tubulin is oriented in microtubules with beta-tubulin toward the plus end [[cite:PUB00006112]].</p> <p>For maximal rate and extent of polymerisation into microtubules, tubulin requires GTP. Two molecules of GTP are bound at different sites, termed N and E. At the E (Exchangeable) site, GTP is hydrolysed during incorporation into the microtubule. Close to the E site is an invariant region rich in glycine residues, which is found in both chains and is thought to control access of the nucleotide to its binding site [[cite:PUB00002443]].</p> <p>Most species, excepting simple eukaryotes, express a variety of closely-related alpha- and beta-isotypes. A third family member, gamma tubulin, has also been identified in a number of species. Gamma tubulin is found at microtubule-organising centres, such as the spindle poles or the centrosome, suggesting that it is involved in minus-end nucleation of microtubule assembly [[cite:PUB00000721]]. Further eukaryotic tubulins (gamma, epsilon, zeta) that are restricted to certain lineages or species have been reported [[cite:PUB00072959], [cite:PUB00099927]].</p> <p>Bacterial and archaeal homologues of tubulin have been discovered. BtubA and BtubB, two bacterial homologues in the genus Prosthecobacter, have probably been derived by horizontal gene transfer [[cite:PUB00072957], [cite:PUB00039756]].</p> <p>This entry represents the extreme C-terminal structural domain of both alpha and beta tubulin. It forms a helix hairpin [[cite:PUB00020380]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | Tubulin gamma-1 chain [Arabidopsis thaliana] gi|15233174|ref|NP_191724.1| | 8 | ||
– | PREDICTED: tubulin beta-2 chain-like [Glycine max] gi|356504309|ref|XP_003520939.1| | 26 | ||
– | PREDICTED: tubulin gamma-1 chain-like isoform X1 [Cicer arietinum] gi|502113903|ref|XP_004494797.1| | 22 | ||
– | Tubulin alpha-7 chain [Medicago truncatula] gi|357466771|ref|XP_003603670.1| | 24 | ||
– | PREDICTED: tubulin gamma-1 chain-like isoform X1 [Cicer arietinum] gi|502113903|ref|XP_004494797.1| | 15 | ||
– | PREDICTED: tubulin alpha-1 chain [Vitis vinifera] gi|225435758|ref|XP_002285721.1| | 23 | ||
– | Alpha-tubulin, partial [Populus alba] gi|403329628|gb|AFR42124.1| | 13 | ||
– | PREDICTED: tubulin beta-1 chain-like [Glycine max] gi|356571899|ref|XP_003554108.1| | 26 | ||
– | Beta-tubulin 16 [Salix arbutifolia] gi|460240332|gb|AGH08237.1| | 26 | ||
– | RecName: Full=Tubulin beta-2 chain; AltName: Full=Beta-2-tubulingi|4415992|gb|AAD20179.1| beta-tubulin 2 [Eleusine indica] gi|8928425|sp|Q9ZPN9.1|TBB2_ELEIN | 17 | ||
– | PREDICTED: tubulin beta-3 chain-like [Cicer arietinum] gi|502141952|ref|XP_004504719.1| | 18 | ||
– | 14 | |||
– | RecName: Full=Tubulin alpha-3 chain; AltName: Full=Alpha-3-tubulingi|2511535|gb|AAC05719.1| alpha-tubulin 3 [Eleusine indica] gi|6094431|sp|O22349.1|TBA3_ELEIN | 25 | ||
– | PREDICTED: tubulin beta-1 chain-like [Cicer arietinum] gi|502139309|ref|XP_004503723.1| | 23 | ||
– | PREDICTED: tubulin beta-1 chain-like [Cicer arietinum] gi|502139309|ref|XP_004503723.1| | 25 | ||
– | PREDICTED: tubulin beta-1 chain-like [Cicer arietinum] gi|502119269|ref|XP_004496560.1| | 26 | ||
– | PREDICTED: tubulin alpha chain-like [Cicer arietinum] gi|502120143|ref|XP_004496862.1| | 23 | ||
– | Tubulin beta chain [Lotus japonicus] gi|244539475|dbj|BAH82659.1| | 26 | ||
– | Tubulin beta chain; TAIR: AT3G61650.1 gamma-tubulin; Swiss-Prot: sp|P38557|TBG1_ARATH Tubulin gamma-1 chain; TrEMBL-Plants: tr|G7L416|G7L416_MEDTR Tubulin gamma chain; Found in the gene: LotjaGi1g1v0042300 | 24 | ||
– | Tubulin beta chain; TAIR: AT3G61650.1 gamma-tubulin; Swiss-Prot: sp|P38557|TBG1_ARATH Tubulin gamma-1 chain; TrEMBL-Plants: tr|G7L416|G7L416_MEDTR Tubulin gamma chain; Found in the gene: LotjaGi1g1v0042300 | 24 | ||
– | Tubulin alpha chain; TAIR: AT1G04820.1 tubulin alpha-4 chain; Swiss-Prot: sp|P46259|TBA1_PEA Tubulin alpha-1 chain; TrEMBL-Plants: tr|A0A0L9UGJ9|A0A0L9UGJ9_PHAAN Tubulin alpha chain; Found in the gene: LotjaGi1g1v0412500 | 26 | ||
– | Tubulin beta chain; TAIR: AT3G61650.1 gamma-tubulin; Swiss-Prot: sp|P38557|TBG1_ARATH Tubulin gamma-1 chain; TrEMBL-Plants: tr|G7L416|G7L416_MEDTR Tubulin gamma chain; Found in the gene: LotjaGi1g1v0545200 | 24 | ||
– | Tubulin beta chain; TAIR: AT3G61650.1 gamma-tubulin; Swiss-Prot: sp|P38557|TBG1_ARATH Tubulin gamma-1 chain; TrEMBL-Plants: tr|G7L416|G7L416_MEDTR Tubulin gamma chain; Found in the gene: LotjaGi1g1v0545200 | 24 | ||
– | Tubulin alpha chain; TAIR: AT5G19770.1 tubulin alpha-3; Swiss-Prot: sp|O22349|TBA3_ELEIN Tubulin alpha-3 chain; TrEMBL-Plants: tr|I1ML11|I1ML11_SOYBN Tubulin alpha chain; Found in the gene: LotjaGi1g1v0643600 | 25 | ||
– | Tubulin alpha chain; TAIR: AT5G19770.1 tubulin alpha-3; Swiss-Prot: sp|O22349|TBA3_ELEIN Tubulin alpha-3 chain; TrEMBL-Plants: tr|I1ML11|I1ML11_SOYBN Tubulin alpha chain; Found in the gene: LotjaGi1g1v0643600 | 25 | ||
– | Tubulin beta chain; TAIR: AT5G12250.1 beta-6 tubulin; Swiss-Prot: sp|P29514|TBB6_ARATH Tubulin beta-6 chain; TrEMBL-Plants: tr|G7L5V0|G7L5V0_MEDTR Tubulin beta chain; Found in the gene: LotjaGi1g1v0659300 | 28 | ||
– | Tubulin beta chain; TAIR: AT5G12250.1 beta-6 tubulin; Swiss-Prot: sp|P29514|TBB6_ARATH Tubulin beta-6 chain; TrEMBL-Plants: tr|G7L5V0|G7L5V0_MEDTR Tubulin beta chain; Found in the gene: LotjaGi1g1v0659300 | 28 | ||
– | Tubulin beta chain; TAIR: AT5G12250.1 beta-6 tubulin; Swiss-Prot: sp|P29514|TBB6_ARATH Tubulin beta-6 chain; TrEMBL-Plants: tr|G7L5V0|G7L5V0_MEDTR Tubulin beta chain; Found in the gene: LotjaGi1g1v0659300 | 28 | ||
– | Tubulin alpha chain; TAIR: AT5G19770.1 tubulin alpha-3; Swiss-Prot: sp|P28752|TBA1_ORYSJ Tubulin alpha-1 chain; TrEMBL-Plants: tr|A0A0L9VLH4|A0A0L9VLH4_PHAAN Tubulin alpha chain; Found in the gene: LotjaGi2g1v0107000 | 26 | ||
– | Tubulin beta chain; TAIR: AT5G62690.1 tubulin beta chain 2; Swiss-Prot: sp|P12460|TBB2_SOYBN Tubulin beta-2 chain; TrEMBL-Plants: tr|I1JLU8|I1JLU8_SOYBN Tubulin beta chain; Found in the gene: LotjaGi3g1v0217800 | 28 | ||
– | Tubulin beta chain; TAIR: AT5G62690.1 tubulin beta chain 2; Swiss-Prot: sp|P12460|TBB2_SOYBN Tubulin beta-2 chain; TrEMBL-Plants: tr|I1JLU8|I1JLU8_SOYBN Tubulin beta chain; Found in the gene: LotjaGi3g1v0217800 | 28 | ||
– | Tubulin beta chain; TAIR: AT5G23860.1 tubulin beta 8; Swiss-Prot: sp|P12460|TBB2_SOYBN Tubulin beta-2 chain; TrEMBL-Plants: tr|I1JLU8|I1JLU8_SOYBN Tubulin beta chain; Found in the gene: LotjaGi3g1v0217800 | 28 | ||
– | Tubulin beta chain; TAIR: AT2G29550.1 tubulin beta-7 chain; Swiss-Prot: sp|Q9ZPP0|TBB1_ELEIN Tubulin beta-1 chain; TrEMBL-Plants: tr|A0A067GIJ4|A0A067GIJ4_CITSI Tubulin beta chain; Found in the gene: LotjaGi4g1v0026900 | 28 | ||
– | Tubulin beta chain; TAIR: AT2G29550.1 tubulin beta-7 chain; Swiss-Prot: sp|Q9ZPP0|TBB1_ELEIN Tubulin beta-1 chain; TrEMBL-Plants: tr|A0A067GIJ4|A0A067GIJ4_CITSI Tubulin beta chain; Found in the gene: LotjaGi4g1v0026900 | 28 | ||
– | Tubulin beta chain; TAIR: AT2G29550.1 tubulin beta-7 chain; Swiss-Prot: sp|Q9ZPP0|TBB1_ELEIN Tubulin beta-1 chain; TrEMBL-Plants: tr|A0A067GIJ4|A0A067GIJ4_CITSI Tubulin beta chain; Found in the gene: LotjaGi4g1v0026900 | 28 | ||
– | Tubulin beta chain; TAIR: AT2G29550.1 tubulin beta-7 chain; Swiss-Prot: sp|Q9ZPP0|TBB1_ELEIN Tubulin beta-1 chain; TrEMBL-Plants: tr|A0A067GIJ4|A0A067GIJ4_CITSI Tubulin beta chain; Found in the gene: LotjaGi4g1v0026900 | 28 | ||
– | Tubulin beta chain; TAIR: AT2G29550.1 tubulin beta-7 chain; Swiss-Prot: sp|Q9ZPP0|TBB1_ELEIN Tubulin beta-1 chain; TrEMBL-Plants: tr|A0A067GIJ4|A0A067GIJ4_CITSI Tubulin beta chain; Found in the gene: LotjaGi4g1v0026900 | 28 | ||
– | Tubulin alpha chain; TAIR: AT5G19770.1 tubulin alpha-3; Swiss-Prot: sp|Q56WH1|TBA3_ARATH Tubulin alpha-3 chain; TrEMBL-Plants: tr|A0A151TKV5|A0A151TKV5_CAJCA Tubulin alpha chain; Found in the gene: LotjaGi4g1v0376700 | 27 | ||
– | Tubulin alpha chain; TAIR: AT5G19770.1 tubulin alpha-3; Swiss-Prot: sp|Q56WH1|TBA3_ARATH Tubulin alpha-3 chain; TrEMBL-Plants: tr|A0A151TKV5|A0A151TKV5_CAJCA Tubulin alpha chain; Found in the gene: LotjaGi4g1v0376700 | 27 | ||
– | Tubulin alpha chain; TAIR: AT5G19770.1 tubulin alpha-3; Swiss-Prot: sp|Q56WH1|TBA3_ARATH Tubulin alpha-3 chain; TrEMBL-Plants: tr|A0A151TKV5|A0A151TKV5_CAJCA Tubulin alpha chain; Found in the gene: LotjaGi4g1v0376700 | 27 | ||
– | Tubulin beta chain; TAIR: AT5G12250.1 beta-6 tubulin; Swiss-Prot: sp|P12459|TBB1_SOYBN Tubulin beta-1 chain; TrEMBL-Plants: tr|A0A1J7HE29|A0A1J7HE29_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0425600 | 27 | ||
– | Tubulin beta chain; TAIR: AT5G12250.1 beta-6 tubulin; Swiss-Prot: sp|P12459|TBB1_SOYBN Tubulin beta-1 chain; TrEMBL-Plants: tr|A0A1J7HE29|A0A1J7HE29_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0425600 | 27 | ||
– | Tubulin beta chain; TAIR: AT5G12250.1 beta-6 tubulin; Swiss-Prot: sp|P12459|TBB1_SOYBN Tubulin beta-1 chain; TrEMBL-Plants: tr|A0A1J7HE29|A0A1J7HE29_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0425600 | 27 | ||
– | Tubulin beta chain; TAIR: AT5G12250.1 beta-6 tubulin; Swiss-Prot: sp|P18025|TBB1_MAIZE Tubulin beta-1 chain; TrEMBL-Plants: tr|A0A151TK69|A0A151TK69_CAJCA Tubulin beta chain; Found in the gene: LotjaGi4g1v0464300 | 28 | ||
– | Tubulin beta chain; TAIR: AT5G12250.1 beta-6 tubulin; Swiss-Prot: sp|P18025|TBB1_MAIZE Tubulin beta-1 chain; TrEMBL-Plants: tr|A0A151TK69|A0A151TK69_CAJCA Tubulin beta chain; Found in the gene: LotjaGi4g1v0464300 | 28 | ||
– | Tubulin beta chain; TAIR: AT1G20010.1 tubulin beta-5 chain; Swiss-Prot: sp|P18025|TBB1_MAIZE Tubulin beta-1 chain; TrEMBL-Plants: tr|A0A0S3RAJ6|A0A0S3RAJ6_PHAAN Tubulin beta chain; Found in the gene: LotjaGi5g1v0005400 | 28 | ||
– | Tubulin beta chain; TAIR: AT5G23860.1 tubulin beta 8; Swiss-Prot: sp|P37392|TBB1_LUPAL Tubulin beta-1 chain; TrEMBL-Plants: tr|A0A058ZXC7|A0A058ZXC7_EUCGR Tubulin beta chain; Found in the gene: LotjaGi5g1v0300100 | 28 | ||
– | Tubulin beta chain; TAIR: AT5G23860.1 tubulin beta 8; Swiss-Prot: sp|P37392|TBB1_LUPAL Tubulin beta-1 chain; TrEMBL-Plants: tr|A0A058ZXC7|A0A058ZXC7_EUCGR Tubulin beta chain; Found in the gene: LotjaGi5g1v0300100 | 28 | ||
– | Tubulin beta chain; TAIR: AT5G23860.1 tubulin beta 8; Swiss-Prot: sp|Q40106|TBB2_LUPAL Tubulin beta-2 chain; TrEMBL-Plants: tr|M5WZG9|M5WZG9_PRUPE Tubulin beta chain; Found in the gene: LotjaGi5g1v0300100 | 24 | ||
– | Tubulin alpha chain; TAIR: AT1G04820.1 tubulin alpha-4 chain; Swiss-Prot: sp|Q6VAF9|TBA4_GOSHI Tubulin alpha-4 chain; TrEMBL-Plants: tr|A0A1J7FT38|A0A1J7FT38_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0319800 | 25 | ||
– | Tubulin beta chain; TAIR: AT5G23860.1 tubulin beta 8; Swiss-Prot: sp|Q40665|TBB3_ORYSJ Tubulin beta-3 chain; TrEMBL-Plants: tr|C5NU06|C5NU06_LOTJA Tubulin beta chain; Found in the gene: LotjaGi6g1v0268300 | 28 | ||
– | Tubulin beta chain; TAIR: AT5G23860.1 tubulin beta 8; Swiss-Prot: sp|Q40665|TBB3_ORYSJ Tubulin beta-3 chain; TrEMBL-Plants: tr|C5NU06|C5NU06_LOTJA Tubulin beta chain; Found in the gene: LotjaGi6g1v0268300 | 28 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 1.92 |