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IPR003130 is a Dynamin GTPase effector.
<p>This entry represents the dynamin GTPase effector domain (GED) found in proteins related to dynamin. Its C-terminal region constitutes one of the helices of the bundle signalling element (BSE) or neck together with the N- and C-terminal regions from the GTPase domain, being in close proximity and functionally linked to it. The N-terminal region of GED is part of the stalk domain [[cite:PUB00072539]].</p> <p>Dynamin is a GTP-hydrolysing protein that is an essential participant in clathrin-mediated endocytosis by cells. It self-assembles into 'collars' in vivo at the necks of invaginated coated pits; the self-assembly of dynamin being coordinated by the GTPase domain. Mutation studies indicate that dynamin functions as a molecular regulator of receptor-mediated endocytosis [[cite:PUB00072539], [cite:PUB00015628]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Molecular function | GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + phosphate. | ||
Molecular function | GTP binding | Interacting selectively and non-covalently with GTP, guanosine triphosphate. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: dynamin-related protein 5A-like isoform 2 [Glycine max] gi|356497327|ref|XP_003517512.1| | 8 | ||
– | Interferon-induced GTP-binding protein Mx [Medicago truncatula] gi|357519157|ref|XP_003629867.1| | 20 | ||
– | PREDICTED: dynamin-related protein 1E-like isoform 1 [Glycine max] gi|356527252|ref|XP_003532226.1| | 22 | ||
– | Dynamin homolog [Astragalus sinicus] gi|6625788|gb|AAF19398.1|AF203882_1 | 28 | ||
– | PREDICTED: dynamin-related protein 1E-like isoform 1 [Glycine max] gi|356520720|ref|XP_003529008.1| | 21 | ||
– | PREDICTED: dynamin-related protein 1E-like [Cicer arietinum] gi|502155644|ref|XP_004510142.1| | 23 | ||
– | PREDICTED: dynamin-related protein 12A-like isoform X1 [Cicer arietinum] gi|502156855|ref|XP_004510671.1| | 17 | ||
– | PREDICTED: dynamin-2B-like [Glycine max] gi|356563206|ref|XP_003549855.1| | 30 | ||
– | PREDICTED: dynamin-related protein 3A-like [Glycine max] gi|356519473|ref|XP_003528397.1| | 28 | ||
– | 9 | |||
– | PREDICTED: dynamin-related protein 5A-like [Cicer arietinum] gi|502139021|ref|XP_004503616.1| | 22 | ||
– | PREDICTED: dynamin-related protein 5A-like [Cicer arietinum] gi|502139021|ref|XP_004503616.1| | 13 | ||
– | PREDICTED: dynamin-related protein 1C-like isoform X1 [Cicer arietinum] gi|502138270|ref|XP_004503345.1| | 23 | ||
– | PREDICTED: dynamin-related protein 1C-like isoform X1 [Cicer arietinum] gi|502138270|ref|XP_004503345.1| | 11 | ||
– | Dynamin 4C-like protein; TAIR: AT1G60500.1 Dynamin related protein 4C; Swiss-Prot: sp|Q9ZP55|DRP4C_ARATH Dynamin-related protein 4C; TrEMBL-Plants: tr|G7L7C0|G7L7C0_MEDTR Dynamin 4C-like protein; Found in the gene: LotjaGi1g1v0191600_LC | 10 | ||
– | Dynamin family protein; TAIR: AT1G60500.1 Dynamin related protein 4C; Swiss-Prot: sp|Q9ZP55|DRP4C_ARATH Dynamin-related protein 4C; TrEMBL-Plants: tr|G7L7C0|G7L7C0_MEDTR Dynamin 4C-like protein; Found in the gene: LotjaGi1g1v0191800 | 21 | ||
– | Dynamin, putative; TAIR: AT3G60190.1 DYNAMIN-like 1E; Swiss-Prot: sp|Q9FNX5|DRP1E_ARATH Dynamin-related protein 1E; TrEMBL-Plants: tr|I1KYV5|I1KYV5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0597700 | 23 | ||
– | Dynamin, putative; TAIR: AT3G60190.1 DYNAMIN-like 1E; Swiss-Prot: sp|Q9FNX5|DRP1E_ARATH Dynamin-related protein 1E; TrEMBL-Plants: tr|I1KYV5|I1KYV5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0597700 | 23 | ||
– | Dynamin-like family protein; TAIR: AT5G42080.1 dynamin-like protein; Swiss-Prot: sp|Q39828|SDL5A_SOYBN Dynamin-related protein 5A; TrEMBL-Plants: tr|A0A151SCZ5|A0A151SCZ5_CAJCA Dynamin-related protein 5A; Found in the gene: LotjaGi2g1v0442100 | 23 | ||
– | Dynamin-like family protein; TAIR: AT5G42080.1 dynamin-like protein; Swiss-Prot: sp|Q39828|SDL5A_SOYBN Dynamin-related protein 5A; TrEMBL-Plants: tr|A0A0L9TH92|A0A0L9TH92_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0442100 | 21 | ||
– | Dynamin-like family protein; TAIR: AT5G42080.1 dynamin-like protein; Swiss-Prot: sp|Q39828|SDL5A_SOYBN Dynamin-related protein 5A; TrEMBL-Plants: tr|A0A151SCZ5|A0A151SCZ5_CAJCA Dynamin-related protein 5A; Found in the gene: LotjaGi2g1v0442100 | 23 | ||
– | Dynamin homolog; TAIR: AT1G59610.1 dynamin-like 3; Swiss-Prot: sp|Q9LQ55|DRP2B_ARATH Dynamin-2B; TrEMBL-Plants: tr|Q9SDX4|Q9SDX4_ASTSI Dynamin homolog; Found in the gene: LotjaGi3g1v0054800 | 31 | ||
– | Dynamin, putative; TAIR: AT3G60190.1 DYNAMIN-like 1E; Swiss-Prot: sp|Q9FNX5|DRP1E_ARATH Dynamin-related protein 1E; TrEMBL-Plants: tr|A0A151SN43|A0A151SN43_CAJCA Dynamin-related protein 1E; Found in the gene: LotjaGi3g1v0073000 | 24 | ||
– | Dynamin, putative; TAIR: AT3G60190.1 DYNAMIN-like 1E; Swiss-Prot: sp|Q9FNX5|DRP1E_ARATH Dynamin-related protein 1E; TrEMBL-Plants: tr|A0A151SN43|A0A151SN43_CAJCA Dynamin-related protein 1E; Found in the gene: LotjaGi3g1v0073000 | 23 | ||
– | Dynamin, putative; TAIR: AT3G60190.1 DYNAMIN-like 1E; Swiss-Prot: sp|Q9FNX5|DRP1E_ARATH Dynamin-related protein 1E; TrEMBL-Plants: tr|A0A151SN43|A0A151SN43_CAJCA Dynamin-related protein 1E; Found in the gene: LotjaGi3g1v0073000 | 23 | ||
– | Dynamin, putative; TAIR: AT3G61760.1 DYNAMIN-like 1B; Swiss-Prot: sp|Q39828|SDL5A_SOYBN Dynamin-related protein 5A; TrEMBL-Plants: tr|A0A0S3SYT0|A0A0S3SYT0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0395300 | 23 | ||
– | Dynamin, putative; TAIR: AT3G61760.1 DYNAMIN-like 1B; Swiss-Prot: sp|Q39828|SDL5A_SOYBN Dynamin-related protein 5A; TrEMBL-Plants: tr|A0A0S3SYT0|A0A0S3SYT0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0395300 | 26 | ||
– | Dynamin family protein; TAIR: AT1G59610.1 dynamin-like 3; Swiss-Prot: sp|Q9LQ55|DRP2B_ARATH Dynamin-2B; TrEMBL-Plants: tr|I1MQT0|I1MQT0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0001200 | 31 | ||
– | Dynamin, putative; TAIR: AT4G33650.1 dynamin-related protein 3A; Swiss-Prot: sp|Q8S944|DRP3A_ARATH Dynamin-related protein 3A; TrEMBL-Plants: tr|K7L2I2|K7L2I2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0040300 | 26 | ||
– | Dynamin, putative; TAIR: AT3G60190.1 DYNAMIN-like 1E; Swiss-Prot: sp|Q9FNX5|DRP1E_ARATH Dynamin-related protein 1E; TrEMBL-Plants: tr|A0A151R3B5|A0A151R3B5_CAJCA Dynamin-related protein 1E; Found in the gene: LotjaGi4g1v0191000 | 24 | ||
– | Dynamin 4C-like protein; TAIR: AT1G60500.1 Dynamin related protein 4C; Swiss-Prot: sp|Q9ZP55|DRP4C_ARATH Dynamin-related protein 4C; TrEMBL-Plants: tr|G7L7C0|G7L7C0_MEDTR Dynamin 4C-like protein; Found in the gene: LotjaGi4g1v0381500_LC | 10 | ||
– | Dynamin 4C-like protein; TAIR: AT1G60500.1 Dynamin related protein 4C; Swiss-Prot: sp|Q9ZP55|DRP4C_ARATH Dynamin-related protein 4C; TrEMBL-Plants: tr|G7L7C0|G7L7C0_MEDTR Dynamin 4C-like protein; Found in the gene: LotjaGi4g1v0381500_LC | 10 | ||
– | Dynamin-like family protein; TAIR: AT5G42080.1 dynamin-like protein; Swiss-Prot: sp|Q39828|SDL5A_SOYBN Dynamin-related protein 5A; TrEMBL-Plants: tr|I1K693|I1K693_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0435900 | 23 | ||
– | Dynamin-like family protein; TAIR: AT5G42080.1 dynamin-like protein; Swiss-Prot: sp|Q39828|SDL5A_SOYBN Dynamin-related protein 5A; TrEMBL-Plants: tr|I1K693|I1K693_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0435900 | 21 | ||
– | Dynamin; TAIR: AT1G14830.1 DYNAMIN-like 1C; Swiss-Prot: sp|Q8LF21|DRP1C_ARATH Dynamin-related protein 1C; TrEMBL-Plants: tr|G7LBF4|G7LBF4_MEDTR Dynamin-like protein 1E; Found in the gene: LotjaGi4g1v0457600 | 24 | ||
– | Dynamin, putative; TAIR: AT4G33650.1 dynamin-related protein 3A; Swiss-Prot: sp|Q8S944|DRP3A_ARATH Dynamin-related protein 3A; TrEMBL-Plants: tr|I1ME12|I1ME12_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0348900 | 25 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 2.78 |