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IPR013819 is a Lipoxygenase, C-terminal.
<p>Lipoxygenases ([ec:1.13.11.-]) are a class of iron-containing dioxygenases which catalyses the hydroperoxidation of lipids, containing a cis,cis-1,4-pentadiene structure. They are common in plants where they may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. In mammals a number of lipoxygenases isozymes are involved in the metabolism of prostaglandins and leukotrienes [[cite:PUB00000045]]. Sequence data is available for the following lipoxygenases:</p> <ul> <li>Plant lipoxygenases ([ec:1.13.11.12]). Plants express a variety of cytosolic isozymes as well as what seems to be a chloroplast isozyme [[cite:PUB00002887]].</li> <li>Mammalian arachidonate 5-lipoxygenase ([ec:1.13.11.34]).</li> <li>Mammalian arachidonate 12-lipoxygenase ([ec:1.13.11.31]).</li> <li>Mammalian arachidonate 15-lipoxygenase B (also known as erythroid cell-specific 15-lipoxygenase; [ec:1.13.11.33]).</li> </ul> <p>The iron atom in lipoxygenases is bound by four ligands, three of which are histidine residues [[cite:PUB00005162]]. Six histidines are conserved in all lipoxygenase sequences, five of them are found clustered in a stretch of 40 amino acids. This region contains two of the three iron-ligands; the other histidines have been shown [[cite:PUB00000363]] to be important for the activity of lipoxygenases.</p> <p>This entry represents the C-terminal region of these proteins.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Molecular function | Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor. | ||
Molecular function | Metal ion binding | Interacting selectively and non-covalently with any metal ion. | ||
Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | Lipoxygenase [Sesbania rostrata] gi|14589309|emb|CAC43237.1| | 20 | ||
– | PREDICTED: probable linoleate 9S-lipoxygenase 5-like [Glycine max] gi|356535079|ref|XP_003536076.1| | 21 | ||
– | Lipoxygenase [Medicago truncatula] gi|357441685|ref|XP_003591120.1| | 14 | ||
– | PREDICTED: probable linoleate 9S-lipoxygenase 5-like [Glycine max] gi|356535079|ref|XP_003536076.1| | 9 | ||
– | Lipoxygenase [Medicago truncatula] gi|357513143|ref|XP_003626860.1| | 17 | ||
– | PREDICTED: linoleate 13S-lipoxygenase 2-1, chloroplastic-like [Cicer arietinum] gi|502148324|ref|XP_004507121.1| | 18 | ||
– | PREDICTED: LOW QUALITY PROTEIN: linoleate 9S-lipoxygenase 6-like [Glycine max] gi|356560677|ref|XP_003548616.1| | 8 | ||
– | PREDICTED: LOW QUALITY PROTEIN: linoleate 9S-lipoxygenase 6-like [Glycine max] gi|356560677|ref|XP_003548616.1| | 14 | ||
– | Lipoxygenase [Pisum sativum] gi|2459611|gb|AAB71759.1| | 18 | ||
– | Lipoxygenase [Cicer arietinum] gi|7208773|emb|CAB76909.1| | 8 | ||
– | Chalcone synthase [Medicago truncatula] gi|357511981|ref|XP_003626279.1| | 8 | ||
– | Lipoxygenase [Corylus avellana] gi|16904543|emb|CAD10740.1| | 18 | ||
– | PREDICTED: linoleate 13S-lipoxygenase 2-1, chloroplastic-like [Glycine max] gi|356575019|ref|XP_003555640.1| | 16 | ||
– | Seed lipoxygenase [Medicago truncatula] gi|357513825|ref|XP_003627201.1| | 26 | ||
– | Seed lipoxygenase-3 [Medicago truncatula] gi|357513769|ref|XP_003627173.1| | 8 | ||
– | Seed lipoxygenase-3 [Medicago truncatula] gi|357513769|ref|XP_003627173.1| | 14 | ||
– | PREDICTED: probable linoleate 9S-lipoxygenase 5-like [Glycine max] gi|356505853|ref|XP_003521704.1| | 17 | ||
– | Seed lipoxygenase-3 [Medicago truncatula] gi|357513769|ref|XP_003627173.1| | 10 | ||
– | Seed lipoxygenase-3 [Medicago truncatula] gi|357513769|ref|XP_003627173.1| | 12 | ||
– | PREDICTED: seed linoleate 9S-lipoxygenase-3-like [Cicer arietinum] gi|502081405|ref|XP_004486857.1| | 20 | ||
– | PREDICTED: seed linoleate 9S-lipoxygenase-3-like [Cicer arietinum] gi|502081405|ref|XP_004486857.1| | 8 | ||
– | Lipoxygenase [Medicago truncatula] gi|357454555|ref|XP_003597558.1| | 8 | ||
– | PREDICTED: seed linoleate 9S-lipoxygenase-2-like [Cicer arietinum] gi|502081408|ref|XP_004486858.1| | 22 | ||
– | Seed lipoxygenase-3 [Medicago truncatula] gi|357513769|ref|XP_003627173.1| | 10 | ||
– | Lipoxygenase [Sesbania rostrata] gi|14589309|emb|CAC43237.1| | 27 | ||
– | Lipoxygenase [Pisum sativum] gi|2459611|gb|AAB71759.1| | 25 | ||
– | Lipoxygenase [Cicer arietinum] gi|7208773|emb|CAB76909.1| | 8 | ||
– | Lipoxygenase [Pisum sativum] gi|2459611|gb|AAB71759.1| | 25 | ||
– | PREDICTED: linoleate 9S-lipoxygenase-like [Glycine max] gi|356525985|ref|XP_003531600.1| | 18 | ||
– | Chain A, Lipoxygenase-3 Treated With Cumene Hydroperoxide] gi|47168807|pdb|1ROV|A | 9 | ||
– | PREDICTED: seed linoleate 9S-lipoxygenase-like [Glycine max] gi|356528825|ref|XP_003532998.1| | 8 | ||
– | Lipoxygenase [Vicia faba] gi|2143422|emb|CAA97845.1| | 8 | ||
– | PREDICTED: linoleate 9S-lipoxygenase-4-like [Glycine max] gi|356508130|ref|XP_003522813.1| | 9 | ||
– | PREDICTED: linoleate 13S-lipoxygenase 2-1, chloroplastic-like [Glycine max] gi|356538919|ref|XP_003537948.1| | 17 | ||
– | PREDICTED: linoleate 13S-lipoxygenase 3-1, chloroplastic-like [Glycine max] gi|356519590|ref|XP_003528455.1| | 12 | ||
– | PREDICTED: lipoxygenase 6, choloroplastic-like [Glycine max] gi|356525142|ref|XP_003531186.1| | 26 | ||
– | Lipoxygenase [Medicago truncatula] gi|357444265|ref|XP_003592410.1| | 25 | ||
– | Lipoxygenase [Medicago truncatula] gi|357444265|ref|XP_003592410.1| | 26 | ||
– | PREDICTED: linoleate 13S-lipoxygenase 2-1, chloroplastic-like [Glycine max] gi|356550899|ref|XP_003543820.1| | 14 | ||
– | PREDICTED: lipoxygenase 3, chloroplastic-like [Glycine max] gi|356546648|ref|XP_003541736.1| | 8 | ||
– | 8 | |||
– | Lipoxygenase; TAIR: AT1G55020.1 lipoxygenase 1; Swiss-Prot: sp|Q43191|LOX15_SOLTU Probable linoleate 9S-lipoxygenase 5; TrEMBL-Plants: tr|I1JRC2|I1JRC2_SOYBN Lipoxygenase; Found in the gene: LotjaGi1g1v0772900 | 30 | ||
– | Lipoxygenase; TAIR: AT1G55020.1 lipoxygenase 1; Swiss-Prot: sp|P09186|LOX3_SOYBN Seed linoleate 9S-lipoxygenase-3; TrEMBL-Plants: tr|O04919|O04919_VICFA Lipoxygenase; Found in the gene: LotjaGi2g1v0238500_LC | 13 | ||
– | Lipoxygenase; TAIR: AT1G55020.1 lipoxygenase 1; Swiss-Prot: sp|P09186|LOX3_SOYBN Seed linoleate 9S-lipoxygenase-3; TrEMBL-Plants: tr|O04919|O04919_VICFA Lipoxygenase; Found in the gene: LotjaGi2g1v0238500_LC | 13 | ||
– | Lipoxygenase; TAIR: AT1G55020.1 lipoxygenase 1; Swiss-Prot: sp|P09918|LOX3_PEA Seed linoleate 9S-lipoxygenase-3; TrEMBL-Plants: tr|G7IS30|G7IS30_MEDTR Lipoxygenase; Found in the gene: LotjaGi3g1v0028300 | 30 | ||
– | Lipoxygenase; TAIR: AT1G55020.1 lipoxygenase 1; Swiss-Prot: sp|P14856|LOX2_PEA Seed linoleate 9S-lipoxygenase-2; TrEMBL-Plants: tr|G7IS29|G7IS29_MEDTR Lipoxygenase; Found in the gene: LotjaGi3g1v0028600 | 30 | ||
– | Lipoxygenase; TAIR: AT3G22400.1 PLAT/LH2 domain-containing lipoxygenase family protein; Swiss-Prot: sp|Q9LUW0|LOX5_ARATH Linoleate 9S-lipoxygenase 5, chloroplastic; TrEMBL-Plants: tr|I1JMA5|I1JMA5_SOYBN Lipoxygenase; Found in the gene: LotjaGi3g1v0274700 | 26 | ||
– | Lipoxygenase; TAIR: AT1G72520.1 PLAT/LH2 domain-containing lipoxygenase family protein; Swiss-Prot: sp|O24371|LOX31_SOLTU Linoleate 13S-lipoxygenase 3-1, chloroplastic; TrEMBL-Plants: tr|Q93YA9|Q93YA9_SESRO Lipoxygenase; Found in the gene: LotjaGi3g1v0413600 | 30 | ||
– | Lipoxygenase; TAIR: AT1G72520.1 PLAT/LH2 domain-containing lipoxygenase family protein; Swiss-Prot: sp|O24371|LOX31_SOLTU Linoleate 13S-lipoxygenase 3-1, chloroplastic; TrEMBL-Plants: tr|Q93YA9|Q93YA9_SESRO Lipoxygenase; Found in the gene: LotjaGi3g1v0413600 | 30 | ||
– | Lipoxygenase; TAIR: AT1G55020.1 lipoxygenase 1; Swiss-Prot: sp|P24095|LOXX_SOYBN Seed linoleate 9S-lipoxygenase; TrEMBL-Plants: tr|O24470|O24470_PEA Lipoxygenase; Found in the gene: LotjaGi3g1v0419600 | 29 | ||
– | Lipoxygenase; TAIR: AT1G55020.1 lipoxygenase 1; Swiss-Prot: sp|P24095|LOXX_SOYBN Seed linoleate 9S-lipoxygenase; TrEMBL-Plants: tr|A0A072TLZ7|A0A072TLZ7_MEDTR Lipoxygenase; Found in the gene: LotjaGi3g1v0419800 | 19 | ||
– | Lipoxygenase; TAIR: AT1G55020.1 lipoxygenase 1; Swiss-Prot: sp|P24095|LOXX_SOYBN Seed linoleate 9S-lipoxygenase; TrEMBL-Plants: tr|A0A151T9A0|A0A151T9A0_CAJCA Lipoxygenase; Found in the gene: LotjaGi3g1v0419800 | 27 | ||
– | Lipoxygenase; TAIR: AT1G55020.1 lipoxygenase 1; Swiss-Prot: sp|P24095|LOXX_SOYBN Seed linoleate 9S-lipoxygenase; TrEMBL-Plants: tr|G7LIZ7|G7LIZ7_MEDTR Lipoxygenase; Found in the gene: LotjaGi3g1v0420000 | 30 | ||
– | Lipoxygenase; TAIR: AT1G55020.1 lipoxygenase 1; Swiss-Prot: sp|P24095|LOXX_SOYBN Seed linoleate 9S-lipoxygenase; TrEMBL-Plants: tr|G7LIZ7|G7LIZ7_MEDTR Lipoxygenase; Found in the gene: LotjaGi3g1v0420100 | 27 | ||
– | Lipoxygenase; TAIR: AT1G55020.1 lipoxygenase 1; Swiss-Prot: sp|P38414|LOX1_LENCU Linoleate 9S-lipoxygenase; TrEMBL-Plants: tr|I1KUQ6|I1KUQ6_SOYBN Lipoxygenase; Found in the gene: LotjaGi3g1v0420400 | 28 | ||
– | Lipoxygenase; TAIR: AT1G55020.1 lipoxygenase 1; Swiss-Prot: sp|P09918|LOX3_PEA Seed linoleate 9S-lipoxygenase-3; TrEMBL-Plants: tr|G7LI99|G7LI99_MEDTR Lipoxygenase; Found in the gene: LotjaGi3g1v0420500 | 30 | ||
– | Lipoxygenase; TAIR: AT1G55020.1 lipoxygenase 1; Swiss-Prot: sp|P09186|LOX3_SOYBN Seed linoleate 9S-lipoxygenase-3; TrEMBL-Plants: tr|G7LI99|G7LI99_MEDTR Lipoxygenase; Found in the gene: LotjaGi3g1v0420800 | 30 | ||
– | Lipoxygenase; TAIR: AT3G45140.1 lipoxygenase 2; Swiss-Prot: sp|O24370|LOX21_SOLTU Linoleate 13S-lipoxygenase 2-1, chloroplastic; TrEMBL-Plants: tr|I3TAA8|I3TAA8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0496700_LC | 15 | ||
– | Lipoxygenase; TAIR: AT3G45140.1 lipoxygenase 2; Swiss-Prot: sp|O24370|LOX21_SOLTU Linoleate 13S-lipoxygenase 2-1, chloroplastic; TrEMBL-Plants: tr|I3TAA8|I3TAA8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0496700_LC | 12 | ||
– | Lipoxygenase; TAIR: AT3G45140.1 lipoxygenase 2; Swiss-Prot: sp|O24370|LOX21_SOLTU Linoleate 13S-lipoxygenase 2-1, chloroplastic; TrEMBL-Plants: tr|A0A151TMH0|A0A151TMH0_CAJCA Lipoxygenase; Found in the gene: LotjaGi3g1v0496800 | 29 | ||
– | Lipoxygenase; TAIR: AT3G45140.1 lipoxygenase 2; Swiss-Prot: sp|O24370|LOX21_SOLTU Linoleate 13S-lipoxygenase 2-1, chloroplastic; TrEMBL-Plants: tr|A0A151TMH0|A0A151TMH0_CAJCA Lipoxygenase; Found in the gene: LotjaGi3g1v0496800 | 17 | ||
– | Lipoxygenase; TAIR: AT3G45140.1 lipoxygenase 2; Swiss-Prot: sp|O24370|LOX21_SOLTU Linoleate 13S-lipoxygenase 2-1, chloroplastic; TrEMBL-Plants: tr|A0A151TMJ6|A0A151TMJ6_CAJCA Lipoxygenase; Found in the gene: LotjaGi3g1v0496900 | 31 | ||
– | Lipoxygenase; TAIR: AT1G17420.1 lipoxygenase 3; Swiss-Prot: sp|Q9LNR3|LOX3_ARATH Lipoxygenase 3, chloroplastic; TrEMBL-Plants: tr|A0A072UMZ6|A0A072UMZ6_MEDTR Lipoxygenase; Found in the gene: LotjaGi4g1v0056400_LC | 9 | ||
– | Lipoxygenase; TAIR: AT1G17420.1 lipoxygenase 3; Swiss-Prot: sp|O24371|LOX31_SOLTU Linoleate 13S-lipoxygenase 3-1, chloroplastic; TrEMBL-Plants: tr|A0A0L9TKT4|A0A0L9TKT4_PHAAN Lipoxygenase; Found in the gene: LotjaGi4g1v0056600 | 10 | ||
– | Lipoxygenase; TAIR: AT1G55020.1 lipoxygenase 1; Swiss-Prot: sp|Q43191|LOX15_SOLTU Probable linoleate 9S-lipoxygenase 5; TrEMBL-Plants: tr|V7BGT3|V7BGT3_PHAVU Lipoxygenase; Found in the gene: LotjaGi5g1v0221100 | 30 | ||
– | Lipoxygenase; TAIR: AT3G22400.1 PLAT/LH2 domain-containing lipoxygenase family protein; Swiss-Prot: sp|Q9LUW0|LOX5_ARATH Linoleate 9S-lipoxygenase 5, chloroplastic; TrEMBL-Plants: tr|I1LE57|I1LE57_SOYBN Lipoxygenase; Found in the gene: LotjaGi5g1v0314800 | 17 | ||
– | Lipoxygenase; TAIR: AT3G22400.1 PLAT/LH2 domain-containing lipoxygenase family protein; Swiss-Prot: sp|Q9LUW0|LOX5_ARATH Linoleate 9S-lipoxygenase 5, chloroplastic; TrEMBL-Plants: tr|G7ID71|G7ID71_MEDTR Lipoxygenase; Found in the gene: LotjaGi5g1v0314800 | 29 | ||
– | Lipoxygenase; TAIR: AT3G45140.1 lipoxygenase 2; Swiss-Prot: sp|O24370|LOX21_SOLTU Linoleate 13S-lipoxygenase 2-1, chloroplastic; TrEMBL-Plants: tr|A0A072VA97|A0A072VA97_MEDTR Linoleate 13S-lipoxygenase 2-1, related protein; Found in the gene: LotjaGi6g1v0195200 | 30 | ||
– | Lipoxygenase; TAIR: AT3G45140.1 lipoxygenase 2; Swiss-Prot: sp|O24370|LOX21_SOLTU Linoleate 13S-lipoxygenase 2-1, chloroplastic; TrEMBL-Plants: tr|A0A0B2SQ26|A0A0B2SQ26_GLYSO Lipoxygenase; Found in the gene: LotjaGi6g1v0195300 | 17 | ||
– | Lipoxygenase; TAIR: AT3G45140.1 lipoxygenase 2; Swiss-Prot: sp|O24370|LOX21_SOLTU Linoleate 13S-lipoxygenase 2-1, chloroplastic; TrEMBL-Plants: tr|A0A072VA97|A0A072VA97_MEDTR Linoleate 13S-lipoxygenase 2-1, related protein; Found in the gene: LotjaGi6g1v0195700 | 17 | ||
– | Lipoxygenase; TAIR: AT1G72520.1 PLAT/LH2 domain-containing lipoxygenase family protein; Swiss-Prot: sp|Q9FNX8|LOX4_ARATH Lipoxygenase 4, chloroplastic; TrEMBL-Plants: tr|I1M240|I1M240_SOYBN Lipoxygenase; Found in the gene: LotjaGi6g1v0331400 | 9 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
SSF48484 | SUPERFAMILY | 1 | 1.41 |