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IPR001678

Source: InterPro

Description

IPR001678 is a SAM-dependent methyltransferase RsmB-F/NOP2-type domain.

<p>This domain is found in a group of class I-like SAM-binding methyltransferases from all cellular organisms. It includes the catalytic core of this enzimes ([interpro:IPR049560]).</p> <p>The catalytic domain of ribosomal RNA cysteine methyltransferases is highly conserved in archaeal, bacterial and eukaryotic proteins [[cite:PUB00072551]]. It is located at the C-terminal end in ribosomal RNA methyltransferase B (RsmB, Sun, Fmu) and Nop2 and towards the N-terminal in RsmF. Escherichia coli RsmB methylates cytosine C967 in 16S rRNA [[cite:PUB00072551]]. RsmF is a multi-site-specific methyltransferase [[cite:PUB00055250]]. Nop2 methylates cytosine C2870 in the 25S rRNA of S. cerevisiae [[cite:PUB00072550]] and is critical for 60S biogenesis [[cite:PUB00014219]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0008168
Molecular function Methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.
Subterm of

Associated Lotus transcripts 28

Transcript Name Description Predicted domains Domain count
Lj0g3v0259609.1
– PREDICTED: tRNA (cytosine(34)-C(5))-methyltransferase-like [Glycine max] gi|356525455|ref|XP_003531340.1|
Domains
10
Lj1g3v1787640.1
– NOL1/NOP2/Sun domain family member 5B [Medicago truncatula] gi|357465793|ref|XP_003603181.1|
Domains
11
Lj1g3v1787640.2
– NOL1/NOP2/Sun domain family member 5B [Medicago truncatula] gi|357465793|ref|XP_003603181.1|
Domains
12
Lj2g3v3085360.1
– Ribosomal RNA small subunit methyltransferase B [Medicago truncatula] gi|357494215|ref|XP_003617396.1|
Domains
13
Lj2g3v3085360.2
– Ribosomal RNA small subunit methyltransferase B [Medicago truncatula] gi|357494215|ref|XP_003617396.1|
Domains
20
Lj2g3v3303470.1
– PREDICTED: ribosomal RNA small subunit methyltransferase B-like [Cicer arietinum] gi|502099597|ref|XP_004491518.1|
Domains
20
Lj2g3v3303470.2
– PREDICTED: ribosomal RNA small subunit methyltransferase B-like [Cicer arietinum] gi|502099597|ref|XP_004491518.1|
Domains
11
Lj4g3v1061080.1
– PREDICTED: multisite-specific tRNA:(cytosine-C(5))-methyltransferase trm4b-like [Cicer arietinum] gi|502153519|ref|XP_004509368.1|
Domains
10
Lj4g3v1061080.2
– PREDICTED: multisite-specific tRNA:(cytosine-C(5))-methyltransferase trm4b-like [Cicer arietinum] gi|502153519|ref|XP_004509368.1|
Domains
13
Lj6g3v0550640.1
– PREDICTED: tRNA (cytosine(34)-C(5))-methyltransferase-like [Glycine max] gi|356538146|ref|XP_003537565.1|
Domains
7
Lj6g3v0550640.2
– TRNA (cytosine-5-)-methyltransferase NSUN2 [Medicago truncatula] gi|357463293|ref|XP_003601928.1|
Domains
14
Lj6g3v0550640.3
– PREDICTED: tRNA (cytosine(34)-C(5))-methyltransferase-like [Glycine max] gi|356538146|ref|XP_003537565.1|
Domains
15
Lj6g3v0727750.1
– S-adenosyl-L-methionine-dependent methyltransferase-like protein [Arabidopsis thaliana] gi|22328952|ref|NP_194390.2|
Domains
18
Lj6g3v0727750.2
– AT5G55920 [Arabidopsis thaliana] gi|222423014|dbj|BAH19490.1|
Domains
15
LotjaGi1g1v0015100.1
– Ribosomal RNA small subunit methyltransferase B; TAIR: AT3G13180.1 NOL1/NOP2/sun family protein / antitermination NusB domain-containing protein; Swiss-Prot: sp|P94464|RSMB_BACSU Probable ribosomal RNA small subunit methyltransferase B; TrEMBL-Plants: tr|G7KEH7|G7KEH7_MEDTR Ribosomal RNA small subunit methyltransferase B; Found in the gene: LotjaGi1g1v0015100
Domains
21
LotjaGi1g1v0015100.2
– Ribosomal RNA small subunit methyltransferase B; TAIR: AT3G13180.1 NOL1/NOP2/sun family protein / antitermination NusB domain-containing protein; Swiss-Prot: sp|Q8EKR0|RSMB_SHEON Ribosomal RNA small subunit methyltransferase B; TrEMBL-Plants: tr|V7B964|V7B964_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0015100
Domains
10
LotjaGi1g1v0015100.3
– Ribosomal RNA small subunit methyltransferase B; TAIR: AT3G13180.1 NOL1/NOP2/sun family protein / antitermination NusB domain-containing protein; Swiss-Prot: sp|P94464|RSMB_BACSU Probable ribosomal RNA small subunit methyltransferase B; TrEMBL-Plants: tr|I1JJK1|I1JJK1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0015100
Domains
20
LotjaGi1g1v0043900.1
– Ribosomal RNA small subunit methyltransferase B; TAIR: AT1G06560.1 NOL1/NOP2/sun family protein; Swiss-Prot: sp|Q7TS68|NSUN6_MOUSE Putative methyltransferase NSUN6; TrEMBL-Plants: tr|K7M4N7|K7M4N7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0043900
Domains
18
LotjaGi1g1v0369100.1
– Ribosomal RNA small subunit methyltransferase B; TAIR: AT5G26180.1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Swiss-Prot: sp|Q96P11|NSUN5_HUMAN Probable 28S rRNA (cytosine-C(5))-methyltransferase; TrEMBL-Plants: tr|I1JTZ9|I1JTZ9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0369100
Domains
13
LotjaGi4g1v0129200.1
– S-adenosyl-L-methionine-dependent methyltransferase superfamily protein; TAIR: AT5G66180.1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Swiss-Prot: sp|A1JRZ3|RSMB_YERE8 Ribosomal RNA small subunit methyltransferase B; TrEMBL-Plants: tr|A0A0B2NYA6|A0A0B2NYA6_GLYSO Putative methyltransferase NSUN5; Found in the gene: LotjaGi4g1v0129200
Domains
10
LotjaGi4g1v0129200.2
– S-adenosyl-L-methionine-dependent methyltransferase superfamily protein; TAIR: AT5G66180.1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Swiss-Prot: sp|O13935|TRM4B_SCHPO Multisite-specific tRNA:(cytosine-C(5))-methyltransferase trm4b; TrEMBL-Plants: tr|I1JCG2|I1JCG2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0129200
Domains
12
LotjaGi4g1v0129200.3
– S-adenosyl-L-methionine-dependent methyltransferase superfamily protein; TAIR: AT5G66180.1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Swiss-Prot: sp|Q96P11|NSUN5_HUMAN Probable 28S rRNA (cytosine-C(5))-methyltransferase; TrEMBL-Plants: tr|I1JCG2|I1JCG2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0129200
Domains
10
LotjaGi4g1v0129200.4
– S-adenosyl-L-methionine-dependent methyltransferase superfamily protein; TAIR: AT5G66180.1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Swiss-Prot: sp|O13935|TRM4B_SCHPO Multisite-specific tRNA:(cytosine-C(5))-methyltransferase trm4b; TrEMBL-Plants: tr|I1JCG2|I1JCG2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0129200
Domains
12
LotjaGi4g1v0395400.1
– Ribosomal RNA small subunit methyltransferase F; TAIR: AT2G22400.1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Swiss-Prot: sp|Q5ZLV4|NSUN2_CHICK tRNA (cytosine(34)-C(5))-methyltransferase; TrEMBL-Plants: tr|A0A0B2PBC2|A0A0B2PBC2_GLYSO tRNA (Cytosine(34)-C(5))-methyltransferase; Found in the gene: LotjaGi4g1v0395400
Domains
14
LotjaGi6g1v0092300.1
– Ribosomal RNA small subunit methyltransferase F; TAIR: AT2G22400.1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Swiss-Prot: sp|Q5ZLV4|NSUN2_CHICK tRNA (cytosine(34)-C(5))-methyltransferase; TrEMBL-Plants: tr|A0A0B2SJ66|A0A0B2SJ66_GLYSO tRNA (Cytosine(34)-C(5))-methyltransferase; Found in the gene: LotjaGi6g1v0092300
Domains
14
LotjaGi6g1v0092300.2
– Ribosomal RNA small subunit methyltransferase F; TAIR: AT2G22400.1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Swiss-Prot: sp|Q5ZLV4|NSUN2_CHICK tRNA (cytosine(34)-C(5))-methyltransferase; TrEMBL-Plants: tr|A0A1J7IQK7|A0A1J7IQK7_LUPAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0092300
Domains
14
LotjaGi6g1v0092300.3
– Ribosomal RNA small subunit methyltransferase F; TAIR: AT2G22400.1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Swiss-Prot: sp|Q5ZLV4|NSUN2_CHICK tRNA (cytosine(34)-C(5))-methyltransferase; TrEMBL-Plants: tr|I1LNJ4|I1LNJ4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0092300
Domains
14
LotjaGi6g1v0141300.1
– Ribosomal RNA small subunit methyltransferase b; TAIR: AT4G26600.1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Swiss-Prot: sp|Q922K7|NOP2_MOUSE Probable 28S rRNA (cytosine-C(5))-methyltransferase; TrEMBL-Plants: tr|I1N087|I1N087_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0141300
Domains
21

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 3.57