Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

GO:0004519

View this GO term in other databases

Overview

Field Value
Namespace Molecular function
Short description Endonuclease activity
Full defintion Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
Subterm of

Relationships

The relationship of GO:0004519 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0004519, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

  • Drag and drop nodes to manually position (i.e. fix) them
  • Double click on a node to unfix the node
  • Press Alt and double click to visit the page containing further details of a GO term
  • Right clicking on a node will reveal a context menu

Controls

Force layout

Every force layout is different—we have picked a set of parameters which suits most GO ancestor tree chart well. If you mess something up—don't worry: hitting the "reset view" button above will reset the chart to its default layout.

Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCmah
ISBN
Oxford Dictionary of Biochemistry and Molecular BiologyOxford Dictionary of Biochemistry and Molecular Biology

Anthony David Smith · ISBN: 0198547684

Oxford University Press, USA, 1997 · 762 pages

Arranged in A-to-Z order, the more than 17,000 entries provide basic information about fundamental, physiochemical laws, chemical compounds, constants, and formulae. The Dictionary also describes the essential features of some 2,000 enzymes and proteins, the reactions they catalyze and the functions they perform. These entries also include filenames to facilitate the location of entries in databases of sequences and definitions of 950 abbreviations and symbols. Designed for students, teachers, researchers and other professionals in any area of the biomedical sciences, the Dictionary has been fully updated anf revised to incorporate new information discovered since the original edition was published in 1997.

Associated Lotus transcripts 50

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj0g3v0322239.1
– PREDICTED: zinc finger Ran-binding domain-containing protein 3-like [Glycine max] gi|356519100|ref|XP_003528212.1|
GO terms
2
Lj0g3v0322239.2
– PREDICTED: zinc finger Ran-binding domain-containing protein 3-like [Glycine max] gi|356519100|ref|XP_003528212.1|
GO terms
2
Lj0g3v0322239.3
– PREDICTED: zinc finger Ran-binding domain-containing protein 3-like [Glycine max] gi|356519100|ref|XP_003528212.1|
GO terms
2
Lj0g3v0322239.4
– PREDICTED: zinc finger Ran-binding domain-containing protein 3-like [Glycine max] gi|356519100|ref|XP_003528212.1|
GO terms
2
Lj1g3v1596960.1
– PREDICTED: double-strand break repair protein MRE11-like [Glycine max] gi|356542248|ref|XP_003539581.1|
GO terms
6
Lj2g3v1130620.1
– Nuclease S1 [Medicago truncatula] gi|357488641|ref|XP_003614608.1|
GO terms
3
Lj2g3v1130630.1
– Endonuclease [Medicago truncatula] gi|357488645|ref|XP_003614610.1|
GO terms
3
Lj2g3v1141860.1
– Nuclease S1 [Medicago truncatula] gi|357488641|ref|XP_003614608.1|
GO terms
3
Lj2g3v1575320.1
– PREDICTED: pentatricopeptide repeat-containing protein At2g15820-like isoform X1 [Cicer arietinum] gi|502126430|ref|XP_004499305.1|
GO terms
1
Lj2g3v2195520.1
– PREDICTED: mutS2 protein-like isoform X2 [Cicer arietinum] gi|502095766|ref|XP_004490532.1|
GO terms
4
Lj2g3v2195520.2
– PREDICTED: mutS2 protein-like isoform X2 [Cicer arietinum] gi|502095766|ref|XP_004490532.1|
GO terms
4
Lj2g3v3019670.1
– LAS1-like protein [Medicago truncatula] gi|357493865|ref|XP_003617221.1|
GO terms
3
Lj2g3v3019680.1
– LAS1-like protein [Medicago truncatula] gi|357493865|ref|XP_003617221.1|
GO terms
3
Lj3g3v0681540.1
– PREDICTED: double-strand break repair protein MRE11-like [Glycine max] gi|356542248|ref|XP_003539581.1|
GO terms
6
Lj4g3v0447880.1
– PREDICTED: endonuclease 4-like isoform X1 [Cicer arietinum] gi|502142497|ref|XP_004504986.1|
GO terms
3
Lj4g3v0451120.1
– PREDICTED: mutS2 protein-like isoform 1 [Glycine max] gi|356521349|ref|XP_003529319.1|
GO terms
4
Lj4g3v0451120.2
– PREDICTED: mutS2 protein-like isoform 1 [Glycine max] gi|356521349|ref|XP_003529319.1|
GO terms
4
Lj5g3v0553270.1
– PREDICTED: endonuclease V [Glycine max] gi|356552555|ref|XP_003544632.1|
GO terms
2
Lj5g3v0553270.2
– PREDICTED: endonuclease V [Glycine max] gi|356552555|ref|XP_003544632.1|
GO terms
2
Lj5g3v0868340.1
– PREDICTED: LOW QUALITY PROTEIN: apurinic endonuclease-redox protein-like [Glycine max] gi|356537505|ref|XP_003537267.1|
GO terms
3
Lj5g3v2183730.1
– PREDICTED: nuclease S1-like [Glycine max] gi|356575560|ref|XP_003555908.1|
GO terms
3
Lj6g3v2078190.1
– Endonuclease [Medicago truncatula] gi|357446373|ref|XP_003593464.1|
GO terms
3
Lj6g3v2078200.1
– Endonuclease, partial [Lotus japonicus] gi|50657594|gb|AAT79581.1|
GO terms
3
LotjaGi1g1v0052000.1
– Ribosomal biogenesis protein LAS1; TAIR: AT5G12220.1 las1-like family protein; Swiss-Prot: sp|Q9Y4W2|LAS1L_HUMAN Ribosomal biogenesis protein LAS1L; TrEMBL-Plants: tr|A0A151U1Y2|A0A151U1Y2_CAJCA LAS1-like protein; Found in the gene: LotjaGi1g1v0052000
GO terms
3
LotjaGi1g1v0127700.1
– DNA mismatch repair MUTS family protein; TAIR: AT5G54090.1 DNA mismatch repair protein MutS, type 2; Swiss-Prot: sp|P73625|MUTS2_SYNY3 Endonuclease MutS2; TrEMBL-Plants: tr|I1JH75|I1JH75_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0127700
GO terms
4
LotjaGi1g1v0127700.2
– DNA mismatch repair MUTS family protein; TAIR: AT5G54090.1 DNA mismatch repair protein MutS, type 2; Swiss-Prot: sp|P73625|MUTS2_SYNY3 Endonuclease MutS2; TrEMBL-Plants: tr|I1JH75|I1JH75_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0127700
GO terms
4
LotjaGi1g1v0191200.1
– DNA/RNA helicase protein; TAIR: AT5G07810.1 SNF2 domain-containing protein / helicase domain-containing protein / HNH endonuclease domain-containing protein; Swiss-Prot: sp|Q6NZP1|ZRAB3_MOUSE DNA annealing helicase and endonuclease ZRANB3; TrEMBL-Plants: tr|V7CJZ0|V7CJZ0_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0191200
GO terms
2
LotjaGi1g1v0605700.2
– Flap endonuclease 1; TAIR: AT3G28030.1 5'-3' exonuclease family protein; Swiss-Prot: sp|Q9ATY5|UVH3_ARATH DNA repair protein UVH3; TrEMBL-Plants: tr|K7K2I9|K7K2I9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0605700
GO terms
4
LotjaGi1g1v0605700.3
– Flap endonuclease 1; TAIR: AT3G28030.1 5'-3' exonuclease family protein; Swiss-Prot: sp|Q9ATY5|UVH3_ARATH DNA repair protein UVH3; TrEMBL-Plants: tr|K7K2I9|K7K2I9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0605700
GO terms
4
LotjaGi2g1v0008500.1
– Pentatricopeptide repeat-containing protein family; TAIR: AT2G15820.1 endonuclease; Swiss-Prot: sp|Q9XIL5|PP154_ARATH Pentatricopeptide repeat-containing protein At2g15820, chloroplastic; TrEMBL-Plants: tr|A0A072VEK1|A0A072VEK1_MEDTR PPR containing plant-like protein; Found in the gene: LotjaGi2g1v0008500
GO terms
1
LotjaGi2g1v0008500.2
– Pentatricopeptide repeat-containing protein family; TAIR: AT2G15820.1 endonuclease; Swiss-Prot: sp|Q9XIL5|PP154_ARATH Pentatricopeptide repeat-containing protein At2g15820, chloroplastic; TrEMBL-Plants: tr|A0A072VEK1|A0A072VEK1_MEDTR PPR containing plant-like protein; Found in the gene: LotjaGi2g1v0008500
GO terms
1
LotjaGi2g1v0066000_LC.1
– Endonuclease/exonuclease/phosphatase family protein; TAIR: AT1G43760.1 DNAse I-like superfamily protein; Swiss-Prot: sp|P14381|YTX2_XENLA Transposon TX1 uncharacterized 149 kDa protein; TrEMBL-Plants: tr|A5CA21|A5CA21_VITVI Putative uncharacterized protein; Found in the gene: LotjaGi2g1v0066000_LC
GO terms
3
LotjaGi2g1v0276000.1
– Nuclease S1; TAIR: AT1G68290.1 endonuclease 2; Swiss-Prot: sp|Q9C9G4|ENDO2_ARATH Endonuclease 2; TrEMBL-Plants: tr|I1J6M1|I1J6M1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0276000
GO terms
3
LotjaGi2g1v0276000.2
– Nuclease S1; TAIR: AT1G68290.1 endonuclease 2; Swiss-Prot: sp|Q9C9G4|ENDO2_ARATH Endonuclease 2; TrEMBL-Plants: tr|A0A1J7HPH3|A0A1J7HPH3_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0276000
GO terms
3
LotjaGi2g1v0276000.3
– Nuclease S1; TAIR: AT1G68290.1 endonuclease 2; Swiss-Prot: sp|Q9C9G4|ENDO2_ARATH Endonuclease 2; TrEMBL-Plants: tr|A0A1J7HPH3|A0A1J7HPH3_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0276000
GO terms
3
LotjaGi3g1v0078900.1
– Double-strand break repair protein Mre11; TAIR: AT5G54260.1 DNA repair and meiosis protein (Mre11); Swiss-Prot: sp|Q9XGM2|MRE11_ARATH Double-strand break repair protein MRE11; TrEMBL-Plants: tr|K7LWB6|K7LWB6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0078900
GO terms
6
LotjaGi3g1v0078900.2
– Double-strand break repair protein MRE11; TAIR: AT5G54260.1 DNA repair and meiosis protein (Mre11); Swiss-Prot: sp|Q9XGM2|MRE11_ARATH Double-strand break repair protein MRE11; TrEMBL-Plants: tr|K7LWB6|K7LWB6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0078900
GO terms
6
LotjaGi3g1v0078900.3
– Double-strand break repair protein MRE11; TAIR: AT5G54260.1 DNA repair and meiosis protein (Mre11); Swiss-Prot: sp|Q9XGM2|MRE11_ARATH Double-strand break repair protein MRE11; TrEMBL-Plants: tr|K7LWB6|K7LWB6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0078900
GO terms
6
LotjaGi3g1v0078900.4
– Double-strand break repair protein MRE11; TAIR: AT5G54260.1 DNA repair and meiosis protein (Mre11); Swiss-Prot: sp|Q9XGM2|MRE11_ARATH Double-strand break repair protein MRE11; TrEMBL-Plants: tr|K7LWB6|K7LWB6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0078900
GO terms
6
LotjaGi4g1v0050700.1
– Nuclease S1; TAIR: AT4G21585.1 endonuclease 4; Swiss-Prot: sp|F4JJL0|ENDO4_ARATH Endonuclease 4; TrEMBL-Plants: tr|I3SW41|I3SW41_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0050700
GO terms
3
LotjaGi4g1v0055400.1
– DNA mismatch repair protein MutS2; TAIR: AT1G65070.2 DNA mismatch repair protein MutS, type 2; Swiss-Prot: sp|P73625|MUTS2_SYNY3 Endonuclease MutS2; TrEMBL-Plants: tr|I1KLI9|I1KLI9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0055400
GO terms
4
LotjaGi4g1v0250000.1
– HNH endonuclease; TAIR: AT3G47490.1 HNH endonuclease; Swiss-Prot: sp|Q96F46|I17RA_HUMAN Interleukin-17 receptor A; TrEMBL-Plants: tr|I3T7Q3|I3T7Q3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0250000
GO terms
2
LotjaGi5g1v0063700.1
– Endonuclease V-like protein; TAIR: AT4G31150.1 endonuclease V family protein; Swiss-Prot: sp|Q8C9A2|ENDOV_MOUSE Endonuclease V; TrEMBL-Plants: tr|A0A151RDK1|A0A151RDK1_CAJCA Putative endonuclease FLJ39025 family; Found in the gene: LotjaGi5g1v0063700
GO terms
2
LotjaGi5g1v0135000.1
– DNA-(apurinic or apyrimidinic site) lyase; TAIR: AT2G41460.1 apurinic endonuclease-redox protein; Swiss-Prot: sp|P45951|ARP_ARATH DNA-(apurinic or apyrimidinic site) lyase, chloroplastic; TrEMBL-Plants: tr|K7K9G6|K7K9G6_SOYBN DNA-(apurinic or apyrimidinic site) lyase; Found in the gene: LotjaGi5g1v0135000
GO terms
3
LotjaGi5g1v0219300.1
– DNA ligase-like protein; TAIR: AT3G05210.1 nucleotide repair protein; Swiss-Prot: sp|Q9MA98|ERCC1_ARATH DNA excision repair protein ERCC-1; TrEMBL-Plants: tr|K7LJM3|K7LJM3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0219300
GO terms
4
LotjaGi5g1v0219300.2
– DNA ligase-like protein; TAIR: AT3G05210.1 nucleotide repair protein; Swiss-Prot: sp|Q9MA98|ERCC1_ARATH DNA excision repair protein ERCC-1; TrEMBL-Plants: tr|K7LJM3|K7LJM3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0219300
GO terms
4
LotjaGi5g1v0339100.1
– Nuclease S1; TAIR: AT1G68290.1 endonuclease 2; Swiss-Prot: sp|Q9C9G4|ENDO2_ARATH Endonuclease 2; TrEMBL-Plants: tr|I1NFK4|I1NFK4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0339100
GO terms
3
LotjaGi6g1v0160400_LC.1
– LINE-1 reverse transcriptase like; TAIR: AT3G24255.4 RNA-directed DNA polymerase (reverse transcriptase)-related family protein; Swiss-Prot: sp|O00370|LORF2_HUMAN LINE-1 retrotransposable element ORF2 protein; TrEMBL-Plants: tr|A0A0B2R0Q2|A0A0B2R0Q2_GLYSO LINE-1 reverse transcriptase like; Found in the gene: LotjaGi6g1v0160400_LC
GO terms
3
LotjaGi6g1v0337400.1
– Nuclease S1; TAIR: AT1G11190.1 bifunctional nuclease i; Swiss-Prot: sp|Q9SXA6|ENDO1_ARATH Endonuclease 1; TrEMBL-Plants: tr|I3SHH3|I3SHH3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0337400
GO terms
3
LotjaGi6g1v0337400.2
– Nuclease S1; TAIR: AT1G11190.1 bifunctional nuclease i; Swiss-Prot: sp|Q9SXA6|ENDO1_ARATH Endonuclease 1; TrEMBL-Plants: tr|I3SHH3|I3SHH3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0337400
GO terms
3

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0006308
Biological process DNA catabolic process 1 2.00