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IPR004160 is a Translation elongation factor EFTu/EF1A, C-terminal.
<p>Elongation factor EF1A (also known as EF-1alpha or EF-Tu) promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. EF1A consists of three structural domains. Release factor eRF3, which governs translation termination, has a similar overall structure. RF3 has an N-terminal extension and a EF1A-like C-terminal region which comprises a GTP-binding domain (G domain) and two β-barrel domains that are similar to the three respective domains of elongation factor EF-Tu/eEF1A [[cite:PUB00007747]]. Archaeal EF1A is both involved in translational elongation and termination, as well as in mRNA surveillance, which explains the lack of an eRF3 orthologue in archaea [[cite:PUB00070083]].</p> <p>This entry represents the C-terminal domain of both EF1A and eRF3, which adopts a β-barrel structure. In EF1A, this domain is involved in binding to both charged tRNA and to EF1B (or EF-Ts, [interpro:IPR001816]) [[cite:PUB00007399]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | 13 | |||
– | Elongation factor 1-alpha (EF1-a) [Cicer arietinum] gi|3319882|emb|CAA06245.1| | 16 | ||
– | PREDICTED: elongation factor Tu, chloroplastic-like [Glycine max] gi|356513781|ref|XP_003525588.1| | 30 | ||
– | PREDICTED: elongation factor Tu, chloroplastic-like isoform 1 [Vitis vinifera] gi|225452282|ref|XP_002271032.1| | 14 | ||
– | PREDICTED: elongation factor 1-alpha-like isoform 1 [Glycine max] gi|356558807|ref|XP_003547694.1| | 26 | ||
– | PREDICTED: elongation factor Tu, mitochondrial-like [Glycine max] gi|356572160|ref|XP_003554238.1| | 29 | ||
– | PREDICTED: elongation factor 1-alpha-like [Cicer arietinum] gi|502091438|ref|XP_004489551.1| | 26 | ||
– | PREDICTED: eukaryotic peptide chain release factor GTP-binding subunit ERF3A-like [Glycine max] gi|356527880|ref|XP_003532534.1| | 25 | ||
– | PREDICTED: eukaryotic peptide chain release factor GTP-binding subunit ERF3A-like [Glycine max] gi|356527880|ref|XP_003532534.1| | 25 | ||
– | PREDICTED: elongation factor Tu, chloroplastic-like [Glycine max] gi|356513781|ref|XP_003525588.1| | 25 | ||
– | PREDICTED: HBS1-like protein-like [Glycine max] gi|356528366|ref|XP_003532775.1| | 25 | ||
– | PREDICTED: HBS1-like protein-like [Glycine max] gi|356512557|ref|XP_003524985.1| | 25 | ||
– | PREDICTED: eukaryotic peptide chain release factor GTP-binding subunit ERF3A-like [Glycine max] gi|356527880|ref|XP_003532534.1| | 18 | ||
– | PREDICTED: elongation factor 1-alpha-like isoform 1 [Glycine max] gi|356558807|ref|XP_003547694.1| | 26 | ||
– | PREDICTED: elongation factor Tu, mitochondrial-like [Cucumis sativus] gi|449436569|ref|XP_004136065.1| | 16 | ||
– | Elongation factor Tu; TAIR: AT4G20360.1 RAB GTPase homolog E1B; Swiss-Prot: sp|P46280|EFTU2_SOYBN Elongation factor Tu, chloroplastic; TrEMBL-Plants: tr|K7KMT9|K7KMT9_SOYBN Elongation factor Tu; Found in the gene: LotjaGi1g1v0198100 | 31 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07920.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|O24534|EF1A_VICFA Elongation factor 1-alpha; TrEMBL-Plants: tr|A0A0R0FM97|A0A0R0FM97_SOYBN Elongation factor 1-alpha; Found in the gene: LotjaGi1g1v0614400 | 26 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07920.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|O24534|EF1A_VICFA Elongation factor 1-alpha; TrEMBL-Plants: tr|A0A0R0FM97|A0A0R0FM97_SOYBN Elongation factor 1-alpha; Found in the gene: LotjaGi1g1v0614400 | 26 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07920.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|O24534|EF1A_VICFA Elongation factor 1-alpha; TrEMBL-Plants: tr|A0A0R0FM97|A0A0R0FM97_SOYBN Elongation factor 1-alpha; Found in the gene: LotjaGi1g1v0614400 | 26 | ||
– | Elongation factor Tu; TAIR: AT4G02930.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|Q9ZT91|EFTM_ARATH Elongation factor Tu, mitochondrial; TrEMBL-Plants: tr|V7CYM1|V7CYM1_PHAVU Elongation factor Tu; Found in the gene: LotjaGi1g1v0730600 | 30 | ||
– | Elongation factor Tu; TAIR: AT4G02930.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|Q9ZT91|EFTM_ARATH Elongation factor Tu, mitochondrial; TrEMBL-Plants: tr|A0A1J7HTE2|A0A1J7HTE2_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0730600 | 14 | ||
– | Elongation factor Tu; TAIR: AT4G02930.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|Q9ZT91|EFTM_ARATH Elongation factor Tu, mitochondrial; TrEMBL-Plants: tr|A0A1J7HTE2|A0A1J7HTE2_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0730600 | 14 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07920.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|O49169|EF1A_MANES Elongation factor 1-alpha; TrEMBL-Plants: tr|B9SPV9|B9SPV9_RICCO Elongation factor 1-alpha; Found in the gene: LotjaGi2g1v0077000 | 27 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07920.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|O49169|EF1A_MANES Elongation factor 1-alpha; TrEMBL-Plants: tr|B9SPV9|B9SPV9_RICCO Elongation factor 1-alpha; Found in the gene: LotjaGi2g1v0077000 | 27 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07920.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|O49169|EF1A_MANES Elongation factor 1-alpha; TrEMBL-Plants: tr|A0A1J7H1G7|A0A1J7H1G7_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0077000 | 23 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07920.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|O49169|EF1A_MANES Elongation factor 1-alpha; TrEMBL-Plants: tr|B9SPV9|B9SPV9_RICCO Elongation factor 1-alpha; Found in the gene: LotjaGi2g1v0077000 | 26 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07930.2 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|P0DH99|EF1A1_ARATH Elongation factor 1-alpha 1; TrEMBL-Plants: tr|F4HUA0|F4HUA0_ARATH Elongation factor 1-alpha; Found in the gene: LotjaGi2g1v0077000 | 18 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07920.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|O64937|EF1A_ORYSJ Elongation factor 1-alpha; TrEMBL-Plants: tr|A0A1J7HKW6|A0A1J7HKW6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0101200 | 26 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07920.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|O64937|EF1A_ORYSJ Elongation factor 1-alpha; TrEMBL-Plants: tr|A0A1J7HKW6|A0A1J7HKW6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0101200 | 26 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07930.2 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|P0DH99|EF1A1_ARATH Elongation factor 1-alpha 1; TrEMBL-Plants: tr|F4HUA0|F4HUA0_ARATH Elongation factor 1-alpha; Found in the gene: LotjaGi2g1v0101200 | 18 | ||
– | Elongation factor Tu; TAIR: AT4G20360.1 RAB GTPase homolog E1B; Swiss-Prot: sp|P46280|EFTU2_SOYBN Elongation factor Tu, chloroplastic; TrEMBL-Plants: tr|K7KMT9|K7KMT9_SOYBN Elongation factor Tu; Found in the gene: LotjaGi4g1v0228100 | 32 | ||
– | Elongation factor 1-alpha, putative; TAIR: AT5G10630.3 Translation elongation factor EF1A/initiation factor IF2gamma family protein; Swiss-Prot: sp|Q5R6Y0|HBS1L_PONAB HBS1-like protein; TrEMBL-Plants: tr|K7KQL0|K7KQL0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0382500 | 27 | ||
– | Elongation factor 1-alpha, putative; TAIR: AT5G10630.1 Translation elongation factor EF1A/initiation factor IF2gamma family protein; Swiss-Prot: sp|Q5R6Y0|HBS1L_PONAB HBS1-like protein; TrEMBL-Plants: tr|K7KQL1|K7KQL1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0382500 | 26 | ||
– | Elongation factor 1-alpha, putative; TAIR: AT5G10630.1 Translation elongation factor EF1A/initiation factor IF2gamma family protein; Swiss-Prot: sp|Q5R6Y0|HBS1L_PONAB HBS1-like protein; TrEMBL-Plants: tr|A0A0R0K1F3|A0A0R0K1F3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0382500 | 19 | ||
– | Elongation factor 1-alpha, putative; TAIR: AT5G10630.3 Translation elongation factor EF1A/initiation factor IF2gamma family protein; Swiss-Prot: sp|Q5R6Y0|HBS1L_PONAB HBS1-like protein; TrEMBL-Plants: tr|K7KQL0|K7KQL0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0382500 | 27 | ||
– | Elongation factor 1-alpha, putative; TAIR: AT5G10630.1 Translation elongation factor EF1A/initiation factor IF2gamma family protein; Swiss-Prot: sp|Q5R6Y0|HBS1L_PONAB HBS1-like protein; TrEMBL-Plants: tr|K7KQL1|K7KQL1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0382500 | 26 | ||
– | Elongation factor 1 alpha; TAIR: AT1G18070.1 Translation elongation factor EF1A/initiation factor IF2gamma family protein; Swiss-Prot: sp|Q8R050|ERF3A_MOUSE Eukaryotic peptide chain release factor GTP-binding subunit ERF3A; TrEMBL-Plants: tr|I1KQH1|I1KQH1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0461900 | 24 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07920.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|P43643|EF1A_TOBAC Elongation factor 1-alpha; TrEMBL-Plants: tr|A0A0L9VMG2|A0A0L9VMG2_PHAAN Elongation factor 1-alpha; Found in the gene: LotjaGi5g1v0263900 | 26 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07930.2 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|P0DH99|EF1A1_ARATH Elongation factor 1-alpha 1; TrEMBL-Plants: tr|F4HUA0|F4HUA0_ARATH Elongation factor 1-alpha; Found in the gene: LotjaGi5g1v0263900 | 18 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07920.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|P43643|EF1A_TOBAC Elongation factor 1-alpha; TrEMBL-Plants: tr|A0A0R0FM97|A0A0R0FM97_SOYBN Elongation factor 1-alpha; Found in the gene: LotjaGi5g1v0263900 | 23 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07920.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|O64937|EF1A_ORYSJ Elongation factor 1-alpha; TrEMBL-Plants: tr|A0A1J7I5T3|A0A1J7I5T3_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0277100 | 26 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07930.2 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|O64937|EF1A_ORYSJ Elongation factor 1-alpha; TrEMBL-Plants: tr|F4HUA0|F4HUA0_ARATH Elongation factor 1-alpha; Found in the gene: LotjaGi5g1v0277100 | 18 | ||
– | Elongation factor 1-alpha; TAIR: AT1G07920.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|O64937|EF1A_ORYSJ Elongation factor 1-alpha; TrEMBL-Plants: tr|A0A1J7I5T3|A0A1J7I5T3_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0277100 | 26 | ||
– | Elongation factor Tu; TAIR: AT4G02930.1 GTP binding Elongation factor Tu family protein; Swiss-Prot: sp|Q9ZT91|EFTM_ARATH Elongation factor Tu, mitochondrial; TrEMBL-Plants: tr|A0A151U0N5|A0A151U0N5_CAJCA Elongation factor Tu; Found in the gene: LotjaGi6g1v0300500 | 30 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd03707 | CDD | 1 | 2.27 |