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IPR008971 is a HSP40/DnaJ peptide-binding.
<p>The Escherichia coli Hsp40 DnaJ and Hsp70 DnaK cooperate in the binding of proteins at intermediate stages of folding, assembly, and translocation across membranes [[cite:PUB00010645]]. Binding of protein substrates to the DnaK C-terminal domain is controlled by ATP binding and hydrolysis in the N-terminal ATPase domain. The interaction of DnaJ with DnaK is mediated at least in part by the highly conserved N-terminal J-domain of DnaJ. The J-domain interaction is localized to the ATPase domain of DnaK and is likely to be dominated by electrostatic interactions. J-domain may tether DnaK to DnaJ-bound substrates, which DnaK then binds with its C-terminal peptide-binding domain. The peptide-binding domain of DnaJ is comprised of a β sandwich made up of 6 β-strands divided into 2 sheets.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Protein folding | The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. | ||
| Molecular function | Unfolded protein binding | Interacting selectively and non-covalently with an unfolded protein. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: dnaJ homolog subfamily B member 13-like [Glycine max] gi|356500637|ref|XP_003519138.1| | 13 | ||
| – | PREDICTED: chaperone protein dnaJ 1, mitochondrial-like [Glycine max] gi|356557132|ref|XP_003546872.1| | 8 | ||
| – | PREDICTED: dnaJ homolog subfamily B member 1-like [Cicer arietinum] gi|502147355|ref|XP_004506751.1| | 19 | ||
| – | PREDICTED: chaperone protein dnaJ 1, mitochondrial-like [Glycine max] gi|356528564|ref|XP_003532871.1| | 8 | ||
| – | PREDICTED: chaperone protein DnaJ-like isoform X3 [Cicer arietinum] gi|502170881|ref|XP_004514938.1| | 8 | ||
| – | PREDICTED: chaperone protein dnaJ 1, mitochondrial-like [Glycine max] gi|356542391|ref|XP_003539650.1| | 8 | ||
| – | Chaperone protein dnaJ [Medicago truncatula] gi|357474457|ref|XP_003607513.1| | 19 | ||
| – | PREDICTED: dnaJ homolog subfamily B member 13-like [Glycine max] gi|356500637|ref|XP_003519138.1| | 8 | ||
| – | PREDICTED: chaperone protein DnaJ-like [Glycine max] gi|356522869|ref|XP_003530065.1| | 32 | ||
| – | PREDICTED: chaperone protein DnaJ-like [Glycine max] gi|356522869|ref|XP_003530065.1| | 18 | ||
| – | PREDICTED: chaperone protein dnaJ 1, mitochondrial-like isoform X2 [Cicer arietinum] gi|502095201|ref|XP_004490397.1| | 26 | ||
| – | PREDICTED: chaperone protein dnaJ 1, mitochondrial-like isoform X3 [Cicer arietinum] gi|502095205|ref|XP_004490398.1| | 26 | ||
| – | PREDICTED: dnaJ homolog subfamily B member 1-like [Glycine max] gi|356508606|ref|XP_003523046.1| | 19 | ||
| – | DnaJ homolog subfamily B member [Medicago truncatula] gi|357466371|ref|XP_003603470.1| | 8 | ||
| – | PREDICTED: dnaJ homolog subfamily B member 13-like [Solanum lycopersicum] gi|460402522|ref|XP_004246761.1| | 19 | ||
| – | PREDICTED: dnaJ homolog subfamily B member 11-like [Glycine max] gi|356505618|ref|XP_003521587.1| | 25 | ||
| – | PREDICTED: dnaJ homolog subfamily B member 11-like [Glycine max] gi|356505618|ref|XP_003521587.1| | 24 | ||
| – | PREDICTED: dnaJ homolog subfamily B member 13-like [Cicer arietinum] gi|502093496|ref|XP_004489963.1| | 18 | ||
| – | TO24-123rc [Taraxacum officinale] gi|75755829|gb|ABA26974.1| | 7 | ||
| – | PREDICTED: chaperone protein DnaJ-like isoform X1 [Cicer arietinum] gi|502080714|ref|XP_004486655.1| | 34 | ||
| – | PREDICTED: chaperone protein dnaJ 2-like [Glycine max] gi|356504601|ref|XP_003521084.1| | 24 | ||
| – | PREDICTED: chaperone protein dnaJ 1, mitochondrial-like [Glycine max] gi|356542391|ref|XP_003539650.1| | 25 | ||
| – | Seed maturation protein PM37 [Glycine max] gi|351724545|ref|NP_001238341.1| | 15 | ||
| – | 15 | |||
| – | PREDICTED: dnaJ homolog subfamily B member 13-like isoform 1 [Glycine max] gi|356517478|ref|XP_003527414.1| | 8 | ||
| – | Seed maturation protein PM37 [Glycine max] gi|351724545|ref|NP_001238341.1| | 14 | ||
| – | Seed maturation protein PM37 [Glycine max] gi|351724545|ref|NP_001238341.1| | 14 | ||
| – | Seed maturation protein PM37 [Glycine max] gi|351724545|ref|NP_001238341.1| | 12 | ||
| – | PREDICTED: dnaJ homolog subfamily B member 4-like [Cicer arietinum] gi|502078082|ref|XP_004485834.1| | 8 | ||
| – | PREDICTED: dnaJ homolog subfamily B member 4-like [Cicer arietinum] gi|502078082|ref|XP_004485834.1| | 18 | ||
| – | DnaJ homolog subfamily B member [Medicago truncatula] gi|357446733|ref|XP_003593642.1| | 19 | ||
| – | Chaperone protein DNAj, putative; TAIR: AT1G28210.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q38813|DNAJ1_ARATH Chaperone protein dnaJ 1, mitochondrial; TrEMBL-Plants: tr|K7K9W1|K7K9W1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0140500 | 25 | ||
| – | Chaperone protein DNAj, putative; TAIR: AT1G28210.2 DNAJ heat shock family protein; Swiss-Prot: sp|Q38813|DNAJ1_ARATH Chaperone protein dnaJ 1, mitochondrial; TrEMBL-Plants: tr|K7K9W1|K7K9W1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0140500 | 31 | ||
| – | Chaperone protein DNAj, putative; TAIR: AT1G28210.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q38813|DNAJ1_ARATH Chaperone protein dnaJ 1, mitochondrial; TrEMBL-Plants: tr|K7M7R2|K7M7R2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0140500 | 28 | ||
| – | Chaperone protein dnaJ, putative; TAIR: AT3G47940.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q80Y75|DJB13_MOUSE DnaJ homolog subfamily B member 13; TrEMBL-Plants: tr|V7CHS3|V7CHS3_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0214200 | 20 | ||
| – | Chaperone protein dnaJ; TAIR: AT1G11040.1 HSP40/DnaJ peptide-binding protein; Swiss-Prot: sp|Q80Y75|DJB13_MOUSE DnaJ homolog subfamily B member 13; TrEMBL-Plants: tr|G7J4X9|G7J4X9_MEDTR DnaJ chaperone carboxy-terminal domain protein; Found in the gene: LotjaGi1g1v0261600 | 9 | ||
| – | Chaperone protein dnaJ; TAIR: AT5G25530.2 DNAJ heat shock family protein; Swiss-Prot: sp|Q9UDY4|DNJB4_HUMAN DnaJ homolog subfamily B member 4; TrEMBL-Plants: tr|I1K906|I1K906_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0389700 | 21 | ||
| – | Chaperone protein dnaJ; TAIR: AT5G01390.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q80Y75|DJB13_MOUSE DnaJ homolog subfamily B member 13; TrEMBL-Plants: tr|V7AJV6|V7AJV6_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0441600 | 20 | ||
| – | Chaperone protein dnaJ, putative; TAIR: AT3G62600.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q9LZK5|DNJ19_ARATH DnaJ protein ERDJ3B; TrEMBL-Plants: tr|I1JQQ6|I1JQQ6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0761200 | 25 | ||
| – | Chaperone protein dnaJ; TAIR: AT2G22360.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q9SJZ7|DNJA6_ARATH Chaperone protein dnaJ A6, chloroplastic; TrEMBL-Plants: tr|I1KT02|I1KT02_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0114200 | 29 | ||
| – | Chaperone protein dnaJ; TAIR: AT2G22360.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q9SJZ7|DNJA6_ARATH Chaperone protein dnaJ A6, chloroplastic; TrEMBL-Plants: tr|I1KT02|I1KT02_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0114200 | 29 | ||
| – | Chaperone protein dnaJ; TAIR: AT2G22360.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q9SJZ7|DNJA6_ARATH Chaperone protein dnaJ A6, chloroplastic; TrEMBL-Plants: tr|I1KT02|I1KT02_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0114200 | 29 | ||
| – | Chaperone protein dnaJ, putative; TAIR: AT5G22060.1 DNAJ homologue 2; Swiss-Prot: sp|P42825|DNAJ2_ARATH Chaperone protein dnaJ 2; TrEMBL-Plants: tr|A0A0D2PQJ2|A0A0D2PQJ2_GOSRA Uncharacterized protein; Found in the gene: LotjaGi2g1v0193500 | 15 | ||
| – | Chaperone protein DnaJ; TAIR: AT3G17830.1 Molecular chaperone Hsp40/DnaJ family protein; Swiss-Prot: sp|Q8DKR7|DNAJ_THEEB Chaperone protein DnaJ; TrEMBL-Plants: tr|I1KJ68|I1KJ68_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0194000 | 30 | ||
| – | Chaperone protein DnaJ; TAIR: AT3G17830.1 Molecular chaperone Hsp40/DnaJ family protein; Swiss-Prot: sp|Q8DKR7|DNAJ_THEEB Chaperone protein DnaJ; TrEMBL-Plants: tr|I1KJ68|I1KJ68_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0194000 | 34 | ||
| – | Chaperone protein dnaJ; TAIR: AT1G80030.1 Molecular chaperone Hsp40/DnaJ family protein; Swiss-Prot: sp|Q8DKR7|DNAJ_THEEB Chaperone protein DnaJ; TrEMBL-Plants: tr|A0A0B2SH79|A0A0B2SH79_GLYSO Chaperone protein DnaJ; Found in the gene: LotjaGi3g1v0008000 | 36 | ||
| – | Chaperone protein DNAj, putative; TAIR: AT5G48030.1 gametophytic factor 2; Swiss-Prot: sp|Q8GWW8|GFA2_ARATH Chaperone protein dnaJ GFA2, mitochondrial; TrEMBL-Plants: tr|A0A151RE69|A0A151RE69_CAJCA Uncharacterized protein; Found in the gene: LotjaGi3g1v0058000 | 29 | ||
| – | Chaperone protein dnaJ, putative; TAIR: AT5G22060.1 DNAJ homologue 2; Swiss-Prot: sp|P42825|DNAJ2_ARATH Chaperone protein dnaJ 2; TrEMBL-Plants: tr|I1JMV0|I1JMV0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0063600 | 29 | ||
| – | Chaperone protein dnaJ, putative; TAIR: AT5G22060.1 DNAJ homologue 2; Swiss-Prot: sp|P42825|DNAJ2_ARATH Chaperone protein dnaJ 2; TrEMBL-Plants: tr|I1KJN5|I1KJN5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0063600 | 29 | ||
| – | Chaperone protein dnaJ, putative; TAIR: AT5G22060.1 DNAJ homologue 2; Swiss-Prot: sp|P42825|DNAJ2_ARATH Chaperone protein dnaJ 2; TrEMBL-Plants: tr|I1JMV0|I1JMV0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0063600 | 29 | ||
| – | Chaperone protein DNAj, putative; TAIR: AT5G48030.1 gametophytic factor 2; Swiss-Prot: sp|Q8GWW8|GFA2_ARATH Chaperone protein dnaJ GFA2, mitochondrial; TrEMBL-Plants: tr|A0A0L9UJX2|A0A0L9UJX2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0124500 | 30 | ||
| – | Chaperone protein dnaJ, putative; TAIR: AT5G22060.1 DNAJ homologue 2; Swiss-Prot: sp|P43644|DNJH_ATRNU DnaJ protein homolog ANJ1; TrEMBL-Plants: tr|A0A0D2PQJ2|A0A0D2PQJ2_GOSRA Uncharacterized protein; Found in the gene: LotjaGi3g1v0184100 | 29 | ||
| – | Chaperone protein dnaJ, putative; TAIR: AT5G22060.1 DNAJ homologue 2; Swiss-Prot: sp|P43644|DNJH_ATRNU DnaJ protein homolog ANJ1; TrEMBL-Plants: tr|A0A0D2PQJ2|A0A0D2PQJ2_GOSRA Uncharacterized protein; Found in the gene: LotjaGi3g1v0184100 | 29 | ||
| – | Chaperone protein dnaJ, putative; TAIR: AT5G22060.1 DNAJ homologue 2; Swiss-Prot: sp|P43644|DNJH_ATRNU DnaJ protein homolog ANJ1; TrEMBL-Plants: tr|A0A0D2VJQ1|A0A0D2VJQ1_GOSRA Uncharacterized protein; Found in the gene: LotjaGi3g1v0184100 | 29 | ||
| – | Chaperone protein dnaJ; TAIR: AT5G01390.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q80Y75|DJB13_MOUSE DnaJ homolog subfamily B member 13; TrEMBL-Plants: tr|V7AJV6|V7AJV6_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0208600 | 20 | ||
| – | Chaperone protein dnaJ; TAIR: AT2G20560.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q5R8J8|DNJB4_PONAB DnaJ homolog subfamily B member 4; TrEMBL-Plants: tr|B7FHS3|B7FHS3_MEDTR DnaJ heat shock family protein; Found in the gene: LotjaGi3g1v0241900 | 20 | ||
| – | Chaperone protein dnaJ; TAIR: AT2G20560.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q9UDY4|DNJB4_HUMAN DnaJ homolog subfamily B member 4; TrEMBL-Plants: tr|B7FHS3|B7FHS3_MEDTR DnaJ heat shock family protein; Found in the gene: LotjaGi3g1v0241900 | 17 | ||
| – | Chaperone protein dnaJ; TAIR: AT2G20560.1 DNAJ heat shock family protein; Swiss-Prot: sp|O89114|DNJB5_MOUSE DnaJ homolog subfamily B member 5; TrEMBL-Plants: tr|C6T8E0|C6T8E0_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi3g1v0447700 | 20 | ||
| – | Chaperone protein dnaJ, putative; TAIR: AT5G22060.1 DNAJ homologue 2; Swiss-Prot: sp|Q04960|DNJH_CUCSA DnaJ protein homolog; TrEMBL-Plants: tr|A0A0D2PQJ2|A0A0D2PQJ2_GOSRA Uncharacterized protein; Found in the gene: LotjaGi3g1v0470700 | 30 | ||
| – | Chaperone protein dnaJ, putative; TAIR: AT5G22060.1 DNAJ homologue 2; Swiss-Prot: sp|Q04960|DNJH_CUCSA DnaJ protein homolog; TrEMBL-Plants: tr|A0A151R8Y4|A0A151R8Y4_CAJCA DnaJ protein isogeny ANJ1; Found in the gene: LotjaGi3g1v0470700 | 30 | ||
| – | Chaperone protein dnaJ, putative; TAIR: AT5G22060.1 DNAJ homologue 2; Swiss-Prot: sp|Q04960|DNJH_CUCSA DnaJ protein homolog; TrEMBL-Plants: tr|A0A151R8Y4|A0A151R8Y4_CAJCA DnaJ protein isogeny ANJ1; Found in the gene: LotjaGi3g1v0470700 | 30 | ||
| – | Chaperone protein dnaJ, putative; TAIR: AT1G59725.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q3MI00|DNJB1_BOVIN DnaJ homolog subfamily B member 1; TrEMBL-Plants: tr|V7C6U9|V7C6U9_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0161400 | 8 | ||
| – | Chaperone protein dnaJ; TAIR: AT5G25530.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q9D832|DNJB4_MOUSE DnaJ homolog subfamily B member 4; TrEMBL-Plants: tr|I1KXP3|I1KXP3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0070500 | 13 | ||
| – | Chaperone protein dnaJ; TAIR: AT2G22360.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q9SJZ7|DNJA6_ARATH Chaperone protein dnaJ A6, chloroplastic; TrEMBL-Plants: tr|A0A151S382|A0A151S382_CAJCA Chaperone protein dnaJ; Found in the gene: LotjaGi6g1v0093400 | 29 | ||
| – | DnaJ protein; TAIR: AT3G08910.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q80Y75|DJB13_MOUSE DnaJ homolog subfamily B member 13; TrEMBL-Plants: tr|A2Q505|A2Q505_MEDTR DnaJ heat shock family protein; Found in the gene: LotjaGi6g1v0328300_LC | 7 | ||
| – | Chaperone protein dnaJ; TAIR: AT2G20560.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q80Y75|DJB13_MOUSE DnaJ homolog subfamily B member 13; TrEMBL-Plants: tr|A0A067JNB8|A0A067JNB8_JATCU Uncharacterized protein; Found in the gene: LotjaGi6g1v0328400 | 20 | ||
| – | Chaperone protein dnaJ; TAIR: AT2G20560.1 DNAJ heat shock family protein; Swiss-Prot: sp|Q80Y75|DJB13_MOUSE DnaJ homolog subfamily B member 13; TrEMBL-Plants: tr|A0A067JNB8|A0A067JNB8_JATCU Uncharacterized protein; Found in the gene: LotjaGi6g1v0328400 | 20 | ||
| – | Chaperone protein dnaJ; TAIR: AT4G28480.2 DNAJ heat shock family protein; Swiss-Prot: sp|Q80Y75|DJB13_MOUSE DnaJ homolog subfamily B member 13; TrEMBL-Plants: tr|A0A067JNB8|A0A067JNB8_JATCU Uncharacterized protein; Found in the gene: LotjaGi6g1v0328400 | 19 | ||
| – | Chaperone protein dnaJ; TAIR: AT1G11040.1 HSP40/DnaJ peptide-binding protein; Swiss-Prot: sp|Q80Y75|DJB13_MOUSE DnaJ homolog subfamily B member 13; TrEMBL-Plants: tr|K7M9M0|K7M9M0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0360800 | 9 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 1.45 |