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IPR000357

Source: InterPro

Description

IPR000357 is a HEAT repeat.

<p>The HEAT repeat is a tandemly repeated, 37-47 amino acid long module occurring in a number of cytoplasmic proteins, including the four name-giving proteins huntingtin, elongation factor 3 (EF3), the 65 kDa alpha regulatory subunit of protein phosphatase 2A (PP2A) and the yeast PI3-kinase TOR1 [[cite:PUB00006179]]. Arrays of HEAT repeats consists of 3 to 36 units forming a rod-like helical structure and appear to function as protein-protein interaction surfaces. It has been noted that many HEAT repeat-containing proteins are involved in intracellular transport processes.</p> <p>In the crystal structure of PP2A PR65/A [[cite:PUB00006180]], the HEAT repeats consist of pairs of antiparallel α-helices [[cite:PUB00006179]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005515
Molecular function Protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
Subterm of

Associated Lotus transcripts 40

Transcript Name Description Predicted domains Domain count
Lj0g3v0359049.1
– PREDICTED: microtubule-associated protein TORTIFOLIA1-like [Cicer arietinum] gi|502093420|ref|XP_004489938.1|
Domains
10
Lj2g3v0742070.1
– PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform-like [Glycine max] gi|356520585|ref|XP_003528942.1|
Domains
11
Lj2g3v0878940.1
– PREDICTED: phosphoinositide 3-kinase regulatory subunit 4-like [Glycine max] gi|356497575|ref|XP_003517635.1|
Domains
30
Lj2g3v1155670.1
– PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform-like [Glycine max] gi|356499699|ref|XP_003518674.1|
Domains
16
Lj4g3v1562770.1
– PREDICTED: microtubule-associated protein TORTIFOLIA1-like [Cicer arietinum] gi|502152205|ref|XP_004508815.1|
Domains
13
Lj4g3v2604270.1
– PREDICTED: importin-5-like isoform X2 [Cicer arietinum] gi|502140730|ref|XP_004504314.1|
Domains
16
Lj5g3v2217170.1
– PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform-like isoform X1 [Cicer arietinum] gi|502120866|ref|XP_004497109.1|
Domains
11
Lj5g3v2246110.1
– PREDICTED: transportin-1-like isoform 1 [Glycine max] gi|356536398|ref|XP_003536725.1|
Domains
13
Lj6g3v2274460.1
– PREDICTED: probable importin subunit beta-4-like [Glycine max] gi|356558485|ref|XP_003547537.1|
Domains
16
LotjaGi1g1v0643800.1
– Importin-5; TAIR: AT5G19820.1 ARM repeat superfamily protein; Swiss-Prot: sp|O00410|IPO5_HUMAN Importin-5; TrEMBL-Plants: tr|A5XEM2|A5XEM2_MEDTR Importin beta-3, putative; Found in the gene: LotjaGi1g1v0643800
Domains
17
LotjaGi1g1v0700900.1
– CLIP-associating-like protein; TAIR: AT2G20190.1 CLIP-associated protein; Swiss-Prot: sp|Q8RWY6|CLASP_ARATH CLIP-associated protein; TrEMBL-Plants: tr|I1JPB4|I1JPB4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0700900
Domains
18
LotjaGi1g1v0700900.2
– CLIP-associating-like protein; TAIR: AT2G20190.1 CLIP-associated protein; Swiss-Prot: sp|Q8RWY6|CLASP_ARATH CLIP-associated protein; TrEMBL-Plants: tr|I1JPB4|I1JPB4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0700900
Domains
18
LotjaGi1g1v0700900.3
– CLIP-associating-like protein; TAIR: AT2G20190.1 CLIP-associated protein; Swiss-Prot: sp|Q8RWY6|CLASP_ARATH CLIP-associated protein; TrEMBL-Plants: tr|I1JPB4|I1JPB4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0700900
Domains
18
LotjaGi2g1v0119400_LC.2
– Importin subunit alpha; TAIR: AT1G50240.2 kinase family with ARM repeat domain-containing protein; Swiss-Prot: sp|Q2QAV0|TIO_ARATH Serine/threonine-protein kinase TIO; TrEMBL-Plants: tr|A0A0S3STR7|A0A0S3STR7_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0119400_LC
Domains
11
LotjaGi2g1v0210500.1
– Serine/threonine protein phosphatase 2A regulatory subunit A; TAIR: AT3G25800.1 protein phosphatase 2A subunit A2; Swiss-Prot: sp|Q38950|2AAB_ARATH Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; TrEMBL-Plants: tr|A0A0L9VHW8|A0A0L9VHW8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0210500
Domains
11
LotjaGi2g1v0210500.3
– Serine/threonine protein phosphatase 2A regulatory subunit A; TAIR: AT3G25800.1 protein phosphatase 2A subunit A2; Swiss-Prot: sp|Q38950|2AAB_ARATH Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; TrEMBL-Plants: tr|A0A0L9VHW8|A0A0L9VHW8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0210500
Domains
11
LotjaGi2g1v0210500.4
– Serine/threonine protein phosphatase 2A regulatory subunit A; TAIR: AT3G25800.1 protein phosphatase 2A subunit A2; Swiss-Prot: sp|Q38950|2AAB_ARATH Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; TrEMBL-Plants: tr|A0A0L9VHW8|A0A0L9VHW8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0210500
Domains
11
LotjaGi2g1v0226200.1
– Kinase family protein; TAIR: AT4G29380.1 protein kinase family protein / WD-40 repeat family protein; Swiss-Prot: sp|Q54S77|VPS15_DICDI Probable serine/threonine-protein kinase vps15; TrEMBL-Plants: tr|I1KJQ8|I1KJQ8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0226200
Domains
30
LotjaGi2g1v0226200.2
– WD repeat-containing protein 3; TAIR: AT4G29380.2 protein kinase family protein / WD-40 repeat family protein; Swiss-Prot: sp|Q54S77|VPS15_DICDI Probable serine/threonine-protein kinase vps15; TrEMBL-Plants: tr|A0A0B2PYS8|A0A0B2PYS8_GLYSO Putative serine/threonine-protein kinase vps15; Found in the gene: LotjaGi2g1v0226200
Domains
20
LotjaGi2g1v0226200.3
– Kinase family protein; TAIR: AT4G29380.1 protein kinase family protein / WD-40 repeat family protein; Swiss-Prot: sp|Q54S77|VPS15_DICDI Probable serine/threonine-protein kinase vps15; TrEMBL-Plants: tr|I1KJQ8|I1KJQ8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0226200
Domains
30
LotjaGi2g1v0278900.1
– Serine/threonine protein phosphatase 2A regulatory subunit A; TAIR: AT3G25800.1 protein phosphatase 2A subunit A2; Swiss-Prot: sp|Q38950|2AAB_ARATH Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; TrEMBL-Plants: tr|V7C7V5|V7C7V5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi2g1v0278900
Domains
15
LotjaGi2g1v0278900.2
– Serine/threonine protein phosphatase 2A regulatory subunit A; TAIR: AT3G25800.1 protein phosphatase 2A subunit A2; Swiss-Prot: sp|Q38950|2AAB_ARATH Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; TrEMBL-Plants: tr|V7C7V5|V7C7V5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi2g1v0278900
Domains
15
LotjaGi2g1v0278900.3
– Serine/threonine protein phosphatase 2A regulatory subunit A; TAIR: AT3G25800.2 protein phosphatase 2A subunit A2; Swiss-Prot: sp|Q38950|2AAB_ARATH Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; TrEMBL-Plants: tr|V7C7V5|V7C7V5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi2g1v0278900
Domains
15
LotjaGi2g1v0278900.4
– Serine/threonine protein phosphatase 2A regulatory subunit A; TAIR: AT3G25800.1 protein phosphatase 2A subunit A2; Swiss-Prot: sp|Q38950|2AAB_ARATH Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; TrEMBL-Plants: tr|V7C7V5|V7C7V5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi2g1v0278900
Domains
11
LotjaGi2g1v0311800.1
– Microtubule-associated protein TORTIFOLIA1; TAIR: AT1G27210.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q93ZH1|TORL4_ARATH TORTIFOLIA1-like protein 4; TrEMBL-Plants: tr|G7K6Y7|G7K6Y7_MEDTR Microtubule-associated TORTIFOLIA-like protein; Found in the gene: LotjaGi2g1v0311800
Domains
16
LotjaGi4g1v0241600.1
– Microtubule-associated protein TORTIFOLIA1; TAIR: AT5G62580.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q6NPR6|TORL3_ARATH TORTIFOLIA1-like protein 3; TrEMBL-Plants: tr|A0A072URB3|A0A072URB3_MEDTR Microtubule-associated TORTIFOLIA-like protein; Found in the gene: LotjaGi4g1v0241600
Domains
12
LotjaGi4g1v0376600.1
– Importin-5; TAIR: AT5G19820.1 ARM repeat superfamily protein; Swiss-Prot: sp|O00410|IPO5_HUMAN Importin-5; TrEMBL-Plants: tr|I1KSC8|I1KSC8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0376600
Domains
17
LotjaGi5g1v0149400.1
– CLIP-associating-like protein; TAIR: AT2G20190.1 CLIP-associated protein; Swiss-Prot: sp|Q8RWY6|CLASP_ARATH CLIP-associated protein; TrEMBL-Plants: tr|A0A072VLE8|A0A072VLE8_MEDTR CLIP-associated protein; Found in the gene: LotjaGi5g1v0149400
Domains
15
LotjaGi5g1v0149400.2
– CLIP-associating-like protein; TAIR: AT2G20190.1 CLIP-associated protein; Swiss-Prot: sp|Q8RWY6|CLASP_ARATH CLIP-associated protein; TrEMBL-Plants: tr|A0A072VLE8|A0A072VLE8_MEDTR CLIP-associated protein; Found in the gene: LotjaGi5g1v0149400
Domains
18
LotjaGi5g1v0149400.3
– CLIP-associating-like protein; TAIR: AT2G20190.1 CLIP-associated protein; Swiss-Prot: sp|Q8RWY6|CLASP_ARATH CLIP-associated protein; TrEMBL-Plants: tr|A0A072VLE8|A0A072VLE8_MEDTR CLIP-associated protein; Found in the gene: LotjaGi5g1v0149400
Domains
15
LotjaGi5g1v0149400.4
– CLIP-associating-like protein; TAIR: AT2G20190.1 CLIP-associated protein; Swiss-Prot: sp|Q8RWY6|CLASP_ARATH CLIP-associated protein; TrEMBL-Plants: tr|A0A072VLE8|A0A072VLE8_MEDTR CLIP-associated protein; Found in the gene: LotjaGi5g1v0149400
Domains
16
LotjaGi5g1v0149400.5
– CLIP-associating-like protein; TAIR: AT2G20190.1 CLIP-associated protein; Swiss-Prot: sp|Q8RWY6|CLASP_ARATH CLIP-associated protein; TrEMBL-Plants: tr|A0A072VLE8|A0A072VLE8_MEDTR CLIP-associated protein; Found in the gene: LotjaGi5g1v0149400
Domains
18
LotjaGi5g1v0149400.6
– CLIP-associating-like protein; TAIR: AT2G20190.1 CLIP-associated protein; Swiss-Prot: sp|Q8RWY6|CLASP_ARATH CLIP-associated protein; TrEMBL-Plants: tr|A0A072VLE8|A0A072VLE8_MEDTR CLIP-associated protein; Found in the gene: LotjaGi5g1v0149400
Domains
18
LotjaGi5g1v0341300.1
– Serine/threonine protein phosphatase 2A regulatory subunit A; TAIR: AT3G25800.1 protein phosphatase 2A subunit A2; Swiss-Prot: sp|Q38950|2AAB_ARATH Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; TrEMBL-Plants: tr|A0A072W1U6|A0A072W1U6_MEDTR Serine/threonine protein phosphatase 2A regulatory subunit A; Found in the gene: LotjaGi5g1v0341300
Domains
11
LotjaGi5g1v0341300.2
– Serine/threonine protein phosphatase 2A regulatory subunit A; TAIR: AT3G25800.1 protein phosphatase 2A subunit A2; Swiss-Prot: sp|Q38950|2AAB_ARATH Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; TrEMBL-Plants: tr|A0A072W1U6|A0A072W1U6_MEDTR Serine/threonine protein phosphatase 2A regulatory subunit A; Found in the gene: LotjaGi5g1v0341300
Domains
11
LotjaGi5g1v0341300.3
– Serine/threonine protein phosphatase 2A regulatory subunit A; TAIR: AT3G25800.1 protein phosphatase 2A subunit A2; Swiss-Prot: sp|Q38950|2AAB_ARATH Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; TrEMBL-Plants: tr|A0A072W1U6|A0A072W1U6_MEDTR Serine/threonine protein phosphatase 2A regulatory subunit A; Found in the gene: LotjaGi5g1v0341300
Domains
11
LotjaGi5g1v0341300.4
– Serine/threonine protein phosphatase 2A regulatory subunit A; TAIR: AT3G25800.1 protein phosphatase 2A subunit A2; Swiss-Prot: sp|Q38950|2AAB_ARATH Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; TrEMBL-Plants: tr|A0A072W1U6|A0A072W1U6_MEDTR Serine/threonine protein phosphatase 2A regulatory subunit A; Found in the gene: LotjaGi5g1v0341300
Domains
11
LotjaGi5g1v0350400.1
– Importin beta-1, putative; TAIR: AT2G16950.2 transportin 1; Swiss-Prot: sp|Q8H0U4|TNPO1_ARATH Transportin-1; TrEMBL-Plants: tr|A0A151TQB2|A0A151TQB2_CAJCA Transportin-1; Found in the gene: LotjaGi5g1v0350400
Domains
14
LotjaGi5g1v0350400.3
– Transportin-1; TAIR: AT2G16950.2 transportin 1; Swiss-Prot: sp|Q8H0U4|TNPO1_ARATH Transportin-1; TrEMBL-Plants: tr|A0A151TQB2|A0A151TQB2_CAJCA Transportin-1; Found in the gene: LotjaGi5g1v0350400
Domains
11
LotjaGi5g1v0350400.4
– Importin beta-1, putative; TAIR: AT2G16950.2 transportin 1; Swiss-Prot: sp|Q8H0U4|TNPO1_ARATH Transportin-1; TrEMBL-Plants: tr|A0A151TQB2|A0A151TQB2_CAJCA Transportin-1; Found in the gene: LotjaGi5g1v0350400
Domains
12

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SSF48371 SUPERFAMILY 1 2.50