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GO:0008536

View this GO term in other databases

Overview

Field Value
Namespace Molecular function
Short description Ran GTPase binding
Full defintion Interacting selectively and non-covalently with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly.
Subterm of

Relationships

The relationship of GO:0008536 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCrn
PMID
Mitotic functions of the Ran GTPase network: the importance of being in the right place at the right time.Di Fiore B, Ciciarello M, Lavia P
Cell Cycle. 2004 Mar; 3 (3): 305–13.PMID: 14726649

The Ran GTPase has important roles in nucleocytoplasmic transport, cell cycle progression, nuclear organization and nuclear envelope (NE) assembly. In this review, we discuss emerging evidence that implicate the Ran GTPase system in mitotic control in mammalian cells. Recent work indicates that members of the Ran network control two fundamental aspects of the mammalian mitotic apparatus: (i) centrosome and spindle pole function, and (ii) kinetochore function. It is also emerging that, after NE breakdown, specific Ran network components assemble in local combinations at crucial sites of the mitotic apparatus. In the light of these findings, the original notion that nucleotide-bound forms of the Ran GTPase are distributed along a unique "gradient" in mitotic cells should be re-examined. Available data also suggest that the Ran system is deregulated in certain cellular contexts: this may represent a favoring condition for the onset and propagation of mitotic errors that can predispose cells to become genetically unstable and facilitate neoplastic growth.

Associated Lotus transcripts 54

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj0g3v0313719.2
– PREDICTED: probable importin-7 homolog isoform X1 [Cicer arietinum] gi|502102327|ref|XP_004492039.1|
GO terms
2
Lj0g3v0358599.1
– PREDICTED: transportin-3-like isoform 2 [Glycine max] gi|356562789|ref|XP_003549651.1|
GO terms
2
Lj1g3v0998740.1
– PREDICTED: importin subunit beta-1-like [Cicer arietinum] gi|502136423|ref|XP_004502681.1|
GO terms
2
Lj1g3v2372280.1
– PREDICTED: importin-11-like [Glycine max] gi|356568126|ref|XP_003552264.1|
GO terms
2
Lj1g3v2811580.1
– PREDICTED: importin-11-like [Glycine max] gi|356568126|ref|XP_003552264.1|
GO terms
2
Lj3g3v2455430.1
– PREDICTED: exportin-2-like isoform 1 [Glycine max] gi|356560135|ref|XP_003548351.1|
GO terms
3
Lj3g3v3627880.1
– PREDICTED: exportin-1-like isoform 1 [Glycine max] gi|356538463|ref|XP_003537723.1|
GO terms
2
Lj3g3v3628910.1
– PREDICTED: exportin-1-like isoform 1 [Glycine max] gi|356538463|ref|XP_003537723.1|
GO terms
2
Lj4g3v2250230.1
– ARM repeat superfamily protein [Theobroma cacao] gi|508714972|gb|EOY06869.1|
GO terms
2
Lj4g3v2604270.1
– PREDICTED: importin-5-like isoform X2 [Cicer arietinum] gi|502140730|ref|XP_004504314.1|
GO terms
2
Lj4g3v3014470.1
– PREDICTED: importin subunit beta-1-like [Glycine max] gi|356523655|ref|XP_003530452.1|
GO terms
2
Lj5g3v2246110.1
– PREDICTED: transportin-1-like isoform 1 [Glycine max] gi|356536398|ref|XP_003536725.1|
GO terms
2
Lj6g3v2274460.1
– PREDICTED: probable importin subunit beta-4-like [Glycine max] gi|356558485|ref|XP_003547537.1|
GO terms
2
LotjaGi1g1v0289100.1
– Importin subunit beta-1; TAIR: AT5G53480.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q9FJD4|IMB1_ARATH Importin subunit beta-1; TrEMBL-Plants: tr|V7ASE2|V7ASE2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0289100
GO terms
2
LotjaGi1g1v0289100.2
– Importin subunit beta-1; TAIR: AT5G53480.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q9FJD4|IMB1_ARATH Importin subunit beta-1; TrEMBL-Plants: tr|V7ASE2|V7ASE2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0289100
GO terms
2
LotjaGi1g1v0443600.1
– Importin-like protein; TAIR: AT3G08960.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q9UI26|IPO11_HUMAN Importin-11; TrEMBL-Plants: tr|K7MTL7|K7MTL7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0443600
GO terms
2
LotjaGi1g1v0443600.2
– Importin-like protein; TAIR: AT3G08960.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q9UI26|IPO11_HUMAN Importin-11; TrEMBL-Plants: tr|K7MTL7|K7MTL7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0443600
GO terms
2
LotjaGi1g1v0443600.3
– Importin-like protein; TAIR: AT3G08960.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q9UI26|IPO11_HUMAN Importin-11; TrEMBL-Plants: tr|K7MTL7|K7MTL7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0443600
GO terms
2
LotjaGi1g1v0443600.4
– Importin-like protein; TAIR: AT3G08960.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q9UI26|IPO11_HUMAN Importin-11; TrEMBL-Plants: tr|K7MTL7|K7MTL7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0443600
GO terms
2
LotjaGi1g1v0529600.1
– Importin-like protein; TAIR: AT2G31660.1 ARM repeat superfamily protein; Swiss-Prot: sp|F4IRR2|SAD2_ARATH Importin beta-like SAD2; TrEMBL-Plants: tr|I1N4Z0|I1N4Z0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0529600
GO terms
2
LotjaGi1g1v0529600.3
– Importin-like protein; TAIR: AT2G31660.1 ARM repeat superfamily protein; Swiss-Prot: sp|F4IRR2|SAD2_ARATH Importin beta-like SAD2; TrEMBL-Plants: tr|I1N4Z0|I1N4Z0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0529600
GO terms
2
LotjaGi1g1v0547000.1
– Importin-like protein; TAIR: AT2G31660.1 ARM repeat superfamily protein; Swiss-Prot: sp|F4IRR2|SAD2_ARATH Importin beta-like SAD2; TrEMBL-Plants: tr|I1N4Z0|I1N4Z0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0547000
GO terms
2
LotjaGi1g1v0547000.2
– Importin-like protein; TAIR: AT3G59020.1 ARM repeat superfamily protein; Swiss-Prot: sp|F4J738|SAD2H_ARATH Importin beta-like SAD2 homolog; TrEMBL-Plants: tr|V7B088|V7B088_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0547000
GO terms
2
LotjaGi1g1v0547200_LC.2
– Importin-like protein; TAIR: AT3G59020.2 ARM repeat superfamily protein; Swiss-Prot: sp|F4J738|SAD2H_ARATH Importin beta-like SAD2 homolog; TrEMBL-Plants: tr|V7B088|V7B088_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0547200_LC
GO terms
2
LotjaGi1g1v0547200_LC.4
– Importin-like protein; TAIR: AT3G59020.2 ARM repeat superfamily protein; Swiss-Prot: sp|F4J738|SAD2H_ARATH Importin beta-like SAD2 homolog; TrEMBL-Plants: tr|V7B088|V7B088_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0547200_LC
GO terms
2
LotjaGi1g1v0557800.10
– Exportin-7; TAIR: AT5G06120.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q5ZLT0|XPO7_CHICK Exportin-7; TrEMBL-Plants: tr|A0A0L9UHI4|A0A0L9UHI4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0557800
GO terms
2
LotjaGi1g1v0800700_LC.1
– Exportin-T; TAIR: AT1G72560.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q7PC79|XPOT_ARATH Exportin-T; TrEMBL-Plants: tr|A0A0S3RIV6|A0A0S3RIV6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0800700_LC
GO terms
4
LotjaGi1g1v0800700_LC.2
– Exportin-T; TAIR: AT1G72560.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q7PC79|XPOT_ARATH Exportin-T; TrEMBL-Plants: tr|A0A0S3RIV6|A0A0S3RIV6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0800700_LC
GO terms
4
LotjaGi2g1v0285500.1
– Importin 9; TAIR: AT1G26170.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q91YE6|IPO9_MOUSE Importin-9; TrEMBL-Plants: tr|A0A072TJ92|A0A072TJ92_MEDTR Importin 9; Found in the gene: LotjaGi2g1v0285500
GO terms
2
LotjaGi2g1v0449000.1
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0S3SEC4|A0A0S3SEC4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000
GO terms
2
LotjaGi2g1v0449000.2
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0S3SEC4|A0A0S3SEC4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000
GO terms
2
LotjaGi2g1v0449000.3
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0S3SEC4|A0A0S3SEC4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000
GO terms
2
LotjaGi2g1v0449000.4
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0S3SEC4|A0A0S3SEC4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000
GO terms
2
LotjaGi2g1v0449000.5
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0S3SEC4|A0A0S3SEC4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000
GO terms
2
LotjaGi2g1v0449000.6
– Exportin-1; TAIR: AT5G17020.2 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0L9V7V7|A0A0L9V7V7_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000
GO terms
2
LotjaGi2g1v0449000.7
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0S3SEC4|A0A0S3SEC4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000
GO terms
2
LotjaGi3g1v0396900.1
– Exportin-2; TAIR: AT2G46520.1 cellular apoptosis susceptibility protein, putative / importin-alpha re-exporter; Swiss-Prot: sp|Q9ZPY7|XPO2_ARATH Exportin-2; TrEMBL-Plants: tr|K7MET7|K7MET7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0396900
GO terms
3
LotjaGi3g1v0396900.2
– Exportin-2; TAIR: AT2G46520.1 cellular apoptosis susceptibility protein, putative / importin-alpha re-exporter; Swiss-Prot: sp|Q9ZPY7|XPO2_ARATH Exportin-2; TrEMBL-Plants: tr|K7MET7|K7MET7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0396900
GO terms
3
LotjaGi3g1v0538500.1
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|I1LII4|I1LII4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0538500
GO terms
2
LotjaGi3g1v0538500.2
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|K7LSJ2|K7LSJ2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0538500
GO terms
2
LotjaGi3g1v0538500.3
– Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|I1LII4|I1LII4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0538500
GO terms
2
LotjaGi4g1v0242600.1
– Transportin-3; TAIR: AT5G62600.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q8GUL2|MOS14_ARATH Transportin MOS14; TrEMBL-Plants: tr|A0A0L9TRZ7|A0A0L9TRZ7_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0242600
GO terms
2
LotjaGi4g1v0311900.1
– Importin beta-like SAD2-like protein; TAIR: AT3G17340.1 ARM repeat superfamily protein; Swiss-Prot: sp|F4J738|SAD2H_ARATH Importin beta-like SAD2 homolog; TrEMBL-Plants: tr|A0A151SSC8|A0A151SSC8_CAJCA Putative importin-7 isogeny; Found in the gene: LotjaGi4g1v0311900
GO terms
2
LotjaGi4g1v0311900.2
– Importin beta-like SAD2-like protein; TAIR: AT3G17340.1 ARM repeat superfamily protein; Swiss-Prot: sp|F4J738|SAD2H_ARATH Importin beta-like SAD2 homolog; TrEMBL-Plants: tr|I1MRW2|I1MRW2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0311900
GO terms
2
LotjaGi4g1v0376600.1
– Importin-5; TAIR: AT5G19820.1 ARM repeat superfamily protein; Swiss-Prot: sp|O00410|IPO5_HUMAN Importin-5; TrEMBL-Plants: tr|I1KSC8|I1KSC8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0376600
GO terms
2
LotjaGi4g1v0437800.1
– Importin subunit beta-1; TAIR: AT5G53480.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q9FJD4|IMB1_ARATH Importin subunit beta-1; TrEMBL-Plants: tr|I1KPN2|I1KPN2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0437800
GO terms
2
LotjaGi4g1v0437800.2
– Importin subunit beta-1; TAIR: AT5G53480.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q9FJD4|IMB1_ARATH Importin subunit beta-1; TrEMBL-Plants: tr|I1KPN2|I1KPN2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0437800
GO terms
2
LotjaGi5g1v0350400.1
– Importin beta-1, putative; TAIR: AT2G16950.2 transportin 1; Swiss-Prot: sp|Q8H0U4|TNPO1_ARATH Transportin-1; TrEMBL-Plants: tr|A0A151TQB2|A0A151TQB2_CAJCA Transportin-1; Found in the gene: LotjaGi5g1v0350400
GO terms
2
LotjaGi5g1v0350400.2
– Importin beta-1, putative; TAIR: AT2G16950.2 transportin 1; Swiss-Prot: sp|Q8H0U4|TNPO1_ARATH Transportin-1; TrEMBL-Plants: tr|A0A0B2RSI8|A0A0B2RSI8_GLYSO Transportin-1; Found in the gene: LotjaGi5g1v0350400
GO terms
2
LotjaGi5g1v0350400.3
– Transportin-1; TAIR: AT2G16950.2 transportin 1; Swiss-Prot: sp|Q8H0U4|TNPO1_ARATH Transportin-1; TrEMBL-Plants: tr|A0A151TQB2|A0A151TQB2_CAJCA Transportin-1; Found in the gene: LotjaGi5g1v0350400
GO terms
2
LotjaGi5g1v0350400.4
– Importin beta-1, putative; TAIR: AT2G16950.2 transportin 1; Swiss-Prot: sp|Q8H0U4|TNPO1_ARATH Transportin-1; TrEMBL-Plants: tr|A0A151TQB2|A0A151TQB2_CAJCA Transportin-1; Found in the gene: LotjaGi5g1v0350400
GO terms
2
LotjaGi5g1v0365400.1
– Importin-like protein; TAIR: AT2G31660.1 ARM repeat superfamily protein; Swiss-Prot: sp|F4IRR2|SAD2_ARATH Importin beta-like SAD2; TrEMBL-Plants: tr|I1KWS2|I1KWS2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0365400
GO terms
2
LotjaGi5g1v0365400.2
– Importin-like protein; TAIR: AT2G31660.1 ARM repeat superfamily protein; Swiss-Prot: sp|F4IRR2|SAD2_ARATH Importin beta-like SAD2; TrEMBL-Plants: tr|I1KWS2|I1KWS2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0365400
GO terms
2
LotjaGi6g1v0360700.2
– Importin beta; TAIR: AT4G27640.1 ARM repeat superfamily protein; Swiss-Prot: sp|O60100|IMB4_SCHPO Probable importin subunit beta-4; TrEMBL-Plants: tr|K7M9M1|K7M9M1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0360700
GO terms
2

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0008536
Molecular function Ran GTPase binding 1 1.85