Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR002464 is a DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site.
<p>A number of eukaryotic and prokaryotic proteins have been characterised [[cite:PUB00003826], [cite:PUB00004037], [cite:PUB00004089]] on the basis of their structural similarity. They all seem to be involved in ATP-dependent, nucleic-acid unwinding. There are two subfamilies of such proteins, the D-E-A-D-box and D-E-A-H-box families. Proteins that belong to the subfamily which have His instead of the second Asp are said to be 'D-E-A-H-box' proteins [[cite:PUB00004089], [cite:PUB00004395], [cite:PUB00003151]].</p> <p>Proteins currently known to belong to this subfamily include yeast PRP2, PRP16, PRP22 and PRP43, involved in various ATP-requiring steps of the pre-mRNA splicing process; fission yeast prh1, which my be involved in pre-mRNA splicing; Drosophila male-less (mle) protein required in males for dosage compensation of X chromosome linked genes; yeast RAD3, a DNA helicase involved in excision repair of DNA damaged by UV light, bulky adducts or cross-linking agents; fission yeast rad15 (rhp3) and mammalian DNA excision repair protein XPD (ERCC-2); yeast CHL1 (or CTF1), which is important for chromosome transmission and normal cell cycle progression in G(2)/M; yeast TPS1, Caenorhabditis elegans hypothetical proteins C06E1.10 and K03H1.2; Poxviruses' early transcription factor 70kDa subunit which acts with RNA polymerase to initiate transcription from early gene promoters; Vaccinia virus putative helicase I8; and Escherichia coli putative RNA helicase hrpA. All these proteins share a number of conserved sequence motifs. Some of them are specific to this family while others are shared by other ATP-binding proteins or by proteins belonging to the helicases 'superfamily' [[cite:PUB00004021]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: probable ATP-dependent RNA helicase DHR1-like [Glycine max] gi|356506353|ref|XP_003521949.1| | 25 | ||
| – | Pre-mRNA splicing factor ATP-dependent RNA helicase-like protein [Medicago truncatula] gi|357463271|ref|XP_003601917.1| | 25 | ||
| – | PREDICTED: probable pre-mRNA-splicing factor ATP-dependent RNA helicase-like [Fragaria vesca subsp]. vesca] gi|470142342|ref|XP_004306870.1| | 34 | ||
| – | Pre-mRNA splicing factor ATP-dependent RNA helicase-like protein [Medicago truncatula] gi|357463271|ref|XP_003601917.1| | 38 | ||
| – | RNA helicase family protein isoform 2 [Theobroma cacao] gi|508774752|gb|EOY22008.1| | 16 | ||
| – | PREDICTED: ATP-dependent RNA helicase DHX8 [Glycine max] gi|356502628|ref|XP_003520120.1| | 22 | ||
| – | PREDICTED: ATP-dependent RNA helicase DHX8 [Glycine max] gi|356502628|ref|XP_003520120.1| | 20 | ||
| – | PREDICTED: ATP-dependent DNA helicase Q-like 5-like isoform X1 [Cicer arietinum] gi|502141185|ref|XP_004504477.1| | 24 | ||
| – | PREDICTED: ATP-dependent DNA helicase Q-like 4A-like isoform X1 [Cicer arietinum] gi|502076854|ref|XP_004485478.1| | 21 | ||
| – | PREDICTED: probable ATP-dependent RNA helicase DHX36-like [Glycine max] gi|356534552|ref|XP_003535817.1| | 25 | ||
| – | PREDICTED: probable ATP-dependent RNA helicase DHX36-like isoform X1 [Cicer arietinum] gi|502122238|ref|XP_004497647.1| | 25 | ||
| – | PREDICTED: ATP-dependent DNA helicase Q-like 4A-like isoform X1 [Cicer arietinum] gi|502076854|ref|XP_004485478.1| | 28 | ||
| – | ATP-dependent RNA helicase; TAIR: AT1G32490.1 RNA helicase family protein; Swiss-Prot: sp|Q8VY00|ESP3_ARATH Pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH1; TrEMBL-Plants: tr|A0A0S3RGD2|A0A0S3RGD2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0467600 | 22 | ||
| – | ATP-dependent RNA helicase, putative; TAIR: AT1G26370.1 RNA helicase family protein; Swiss-Prot: sp|F4IE66|PRP22_ARATH Pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH10; TrEMBL-Plants: tr|K7K7U5|K7K7U5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0718000 | 23 | ||
| – | ATP-dependent RNA helicase, putative; TAIR: AT1G26370.1 RNA helicase family protein; Swiss-Prot: sp|F4IE66|PRP22_ARATH Pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH10; TrEMBL-Plants: tr|K7K7U5|K7K7U5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0718000 | 21 | ||
| – | ATP-dependent RNA helicase, putative; TAIR: AT1G26370.1 RNA helicase family protein; Swiss-Prot: sp|F4IE66|PRP22_ARATH Pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH10; TrEMBL-Plants: tr|K7K7U5|K7K7U5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0718000 | 21 | ||
| – | ATP-dependent RNA helicase, putative; TAIR: AT1G33390.1 RNA helicase family protein; Swiss-Prot: sp|Q9C813|DEAHD_ARATH ATP-dependent RNA helicase DEAH13; TrEMBL-Plants: tr|I1J7X3|I1J7X3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0125300 | 26 | ||
| – | ATP-dependent RNA helicase, putative; TAIR: AT1G33390.1 RNA helicase family protein; Swiss-Prot: sp|Q9C813|DEAHD_ARATH ATP-dependent RNA helicase DEAH13; TrEMBL-Plants: tr|I1J7X3|I1J7X3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0317100 | 28 | ||
| – | ATP-dependent RNA helicase DeaD; TAIR: AT1G27880.1 DEAD/DEAH box RNA helicase family protein; Swiss-Prot: sp|Q0WVW7|RQL5_ARATH ATP-dependent DNA helicase Q-like 5; TrEMBL-Plants: tr|I1KRZ4|I1KRZ4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0329000 | 21 | ||
| – | Helicase-related family protein; TAIR: AT1G20720.2 RAD3-like DNA-binding helicase protein; Swiss-Prot: sp|Q5SXJ3|FANCJ_MOUSE Fanconi anemia group J protein homolog; TrEMBL-Plants: tr|K7M8G7|K7M8G7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0000800 | 20 | ||
| – | Helicase-related family protein; TAIR: AT1G20720.2 RAD3-like DNA-binding helicase protein; Swiss-Prot: sp|Q3YK19|FANCJ_CHICK Fanconi anemia group J protein homolog; TrEMBL-Plants: tr|K7M8G7|K7M8G7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0000800 | 18 | ||
| – | ATP-dependent RNA helicase family protein; TAIR: AT3G26560.1 ATP-dependent RNA helicase; Swiss-Prot: sp|Q38953|DEAH5_ARATH Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH5; TrEMBL-Plants: tr|A0A1J7GSK6|A0A1J7GSK6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0008200 | 34 | ||
| – | ATP-dependent RNA helicase, putative; TAIR: AT3G26560.1 ATP-dependent RNA helicase; Swiss-Prot: sp|Q38953|DEAH5_ARATH Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH5; TrEMBL-Plants: tr|V7CUW8|V7CUW8_PHAVU Uncharacterized protein; Found in the gene: LotjaGi5g1v0008200 | 25 | ||
| – | ATP-dependent RNA helicase family protein; TAIR: AT3G26560.1 ATP-dependent RNA helicase; Swiss-Prot: sp|Q38953|DEAH5_ARATH Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH5; TrEMBL-Plants: tr|A0A1J7GSK6|A0A1J7GSK6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0008200 | 34 | ||
| – | ATP-dependent RNA helicase; TAIR: AT2G35920.1 RNA helicase family protein; Swiss-Prot: sp|F4ILR7|DEXH1_ARATH DExH-box ATP-dependent RNA helicase DExH1; TrEMBL-Plants: tr|I1L9L1|I1L9L1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0106200 | 26 | ||
| – | ATP-dependent RNA helicase; TAIR: AT2G35920.1 RNA helicase family protein; Swiss-Prot: sp|F4ILR7|DEXH1_ARATH DExH-box ATP-dependent RNA helicase DExH1; TrEMBL-Plants: tr|K7K9K1|K7K9K1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0106200 | 26 | ||
| – | ATP-dependent RNA helicase; TAIR: AT2G35920.2 RNA helicase family protein; Swiss-Prot: sp|F4ILR7|DEXH1_ARATH DExH-box ATP-dependent RNA helicase DExH1; TrEMBL-Plants: tr|A0A0B2SVY7|A0A0B2SVY7_GLYSO Putative ATP-dependent RNA helicase DHX36; Found in the gene: LotjaGi5g1v0106200 | 29 | ||
| – | ATP-dependent RNA helicase; TAIR: AT2G35920.1 RNA helicase family protein; Swiss-Prot: sp|F4ILR7|DEXH1_ARATH DExH-box ATP-dependent RNA helicase DExH1; TrEMBL-Plants: tr|I1L9L1|I1L9L1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0106200 | 26 | ||
| – | ATP-dependent RNA helicase; TAIR: AT2G35920.1 RNA helicase family protein; Swiss-Prot: sp|F4ILR7|DEXH1_ARATH DExH-box ATP-dependent RNA helicase DExH1; TrEMBL-Plants: tr|I1L9L1|I1L9L1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0106200 | 26 | ||
| – | ATP-dependent RNA helicase; TAIR: AT2G35920.2 RNA helicase family protein; Swiss-Prot: sp|F4ILR7|DEXH1_ARATH DExH-box ATP-dependent RNA helicase DExH1; TrEMBL-Plants: tr|K7K9K1|K7K9K1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0106200 | 26 | ||
| – | ATP-dependent RNA helicase, putative; TAIR: AT5G10370.1 helicase domain-containing protein / IBR domain-containing protein / zinc finger protein-like protein; Swiss-Prot: sp|F4KGU4|DEAHC_ARATH ATP-dependent RNA helicase DEAH12, chloroplastic; TrEMBL-Plants: tr|G7J375|G7J375_MEDTR Helicase, IBR and zinc finger protein; Found in the gene: LotjaGi5g1v0357200 | 40 | ||
| – | ATP-dependent RNA helicase, putative; TAIR: AT5G10370.1 helicase domain-containing protein / IBR domain-containing protein / zinc finger protein-like protein; Swiss-Prot: sp|F4KGU4|DEAHC_ARATH ATP-dependent RNA helicase DEAH12, chloroplastic; TrEMBL-Plants: tr|A0A0B2RGE0|A0A0B2RGE0_GLYSO Uncharacterized protein; Found in the gene: LotjaGi5g1v0357200 | 37 | ||
| – | ATP-dependent RNA helicase, putative; TAIR: AT5G10370.1 helicase domain-containing protein / IBR domain-containing protein / zinc finger protein-like protein; Swiss-Prot: sp|F4KGU4|DEAHC_ARATH ATP-dependent RNA helicase DEAH12, chloroplastic; TrEMBL-Plants: tr|G7J375|G7J375_MEDTR Helicase, IBR and zinc finger protein; Found in the gene: LotjaGi6g1v0090600 | 40 | ||
| – | ATP-dependent RNA helicase; TAIR: AT1G32490.1 RNA helicase family protein; Swiss-Prot: sp|Q8VY00|ESP3_ARATH Pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH1; TrEMBL-Plants: tr|K7KW48|K7KW48_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0196200 | 24 | ||
| – | ATP-dependent RNA helicase; TAIR: AT1G32490.2 RNA helicase family protein; Swiss-Prot: sp|Q8VY00|ESP3_ARATH Pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH1; TrEMBL-Plants: tr|A0A1J7HYM9|A0A1J7HYM9_LUPAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0196200 | 22 | ||
| – | ATP-dependent RNA helicase, putative; TAIR: AT1G32490.1 RNA helicase family protein; Swiss-Prot: sp|Q8VY00|ESP3_ARATH Pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH1; TrEMBL-Plants: tr|K7KW48|K7KW48_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0196200 | 22 | ||
| – | ATP-dependent RNA helicase, putative; TAIR: AT4G18465.1 RNA helicase family protein; Swiss-Prot: sp|F4JRJ6|DEAH9_ARATH Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH9; TrEMBL-Plants: tr|A0A151QUU8|A0A151QUU8_CAJCA Putative ATP-dependent RNA helicase DHX35; Found in the gene: LotjaGi6g1v0325700 | 24 | ||
| – | ATP-dependent RNA helicase DeaD; TAIR: AT1G10930.1 DNA helicase (RECQl4A); Swiss-Prot: sp|Q8L840|RQL4A_ARATH ATP-dependent DNA helicase Q-like 4A; TrEMBL-Plants: tr|G7INR2|G7INR2_MEDTR ATP-dependent DNA helicase RecQ family protein; Found in the gene: LotjaGi6g1v0361700 | 36 | ||
| – | ATP-dependent RNA helicase DeaD; TAIR: AT1G10930.1 DNA helicase (RECQl4A); Swiss-Prot: sp|Q8L840|RQL4A_ARATH ATP-dependent DNA helicase Q-like 4A; TrEMBL-Plants: tr|G7INR2|G7INR2_MEDTR ATP-dependent DNA helicase RecQ family protein; Found in the gene: LotjaGi6g1v0361700 | 36 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 2.56 |